Objective;To explore the diagnosis,treatment and prognosis of the primary ovarian non-Hodgkins lymphoma(PONHL). Methods:Retrospective analysis of 32 patients with ovarian NHL(5 of them received subsequent treatment...
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Objective;To explore the diagnosis,treatment and prognosis of the primary ovarian non-Hodgkins lymphoma(PONHL). Methods:Retrospective analysis of 32 patients with ovarian NHL(5 of them received subsequent treatment after our consultation) had received therapy as surgery,chemotherapy and radiotherapy from Jan.1995 to Jan. 2012 inShengjing Hosptial,ChinaMedical *** Kaplan-Meier method for survival analysis,and Log-rank method for difference test of different survival curve. Results;Clinical manifestation of 32 patients;22 patients of abdominal pain,19 cases of abdomen en-closed mass,10 cases of abdominal distension,hypomenorrhea or oligomenorrhea in 6 patients,4 cases of ascites, 3 cases vaginal bleeding.5 cases with neighboring or distant lymph node invasion or organ infiltration;retroperitoneal lymph nodes in 4 cases,left supraclavicular lymph nodes in 1,1 case with bowel,whole body in 2 cases. 15 cases with peripheral blood CA125 rise(70 -390 u/ml),6 cases of lactate dehydrogenase rise(351—750 u/L).2 cases found malignant tumor cells in *** lesion scope biggest32 cm×26 cm×20 cm, minimum5 cmx4 cmx2 cm,Tumor diameter;7 cases with omentectomy and appendectomy;3 cases with partial intestinal resection and anastomosis;1 case with exploratory laparotomy for the operation difficulty.2 cases with postoperative radiotherapy with 60Co bar radiation in 20 -35Gy,23 cases with postoperative chemotherapy by CHOP or COP from 1 to 12 cycle,9 cases with neither radiotherapy nor *** to the WHO curative effect evaluation standard;divided into complete remission(CR),partial relief(PR),stable disease (SD) and progression of disease(PD ).Survival time from diagnosis to death or last follow-up *** pathologic diagnosis;29 cases of Diffuse large B cell lymphoma(DLBCL);1 case of Burkitt lymphoma;1 case of anaplastic large cell lymphoma,T cells sources;1 case of bilateral ovarian NHL not classification,T cells sources.23 patients had b
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