Background Kinesin-like protein gene 1B(KIF1B)has been reported as a tumor suppressor,recent studies have strongly revealed the association between the single nucleotide polymorphisms(SNP)of rsl7401966(A>G)at lp36 ...
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Background Kinesin-like protein gene 1B(KIF1B)has been reported as a tumor suppressor,recent studies have strongly revealed the association between the single nucleotide polymorphisms(SNP)of rsl7401966(A>G)at lp36 and risk of HBV-related hepatocellular carcinoma(HCC).However,some studies denied their ***,our meta-analysis would be necessary to confirm this *** A total of 15 case-control cohorts,including 7,
Background and aims The system for cell culture of infectious HCV particles(HCVcc)has been established;the purified HCVcc were analysis by the lectin antibody *** aimed to confirm unique glycosylation patterns of *** ...
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Background and aims The system for cell culture of infectious HCV particles(HCVcc)has been established;the purified HCVcc were analysis by the lectin antibody *** aimed to confirm unique glycosylation patterns of *** and material RNA that was synthesized from pJ6/JFHl was mixed with DMRIE-C(invitrogen,UK)in a ratio of 1:*** mixture was transferred into Huh7.5cells *** infected cells were cultured in 2%fetal bo-
Aim The reason why the majority of chronic hepatitis B(CHB)patients do not respond to conventional interferon a(IFNα)or pegylated interferon(Peg-IFN)treatment has not been formally *** aim of this study was to invest...
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Aim The reason why the majority of chronic hepatitis B(CHB)patients do not respond to conventional interferon a(IFNα)or pegylated interferon(Peg-IFN)treatment has not been formally *** aim of this study was to investigate the association between single nucleotide polymorphisms(SNPs)and response to IFNa or Peg-IFN therapy in Chinese patients with *** Four SNPs among the HLA-DPA1,HLA-DPB1 and IL28B regions were genotyped using the MGB-TaqMan SNP genotyping assay in 144 HBeAg seropositive CHB patients who
The profile of T cell receptor beta variable（TCRBV）usually skewed in subjects with virus infection or *** gene melting spectral pattern（GMSP）can be used to determine the profile of TCRBV gene *** explore the portr...
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The profile of T cell receptor beta variable（TCRBV）usually skewed in subjects with virus infection or *** gene melting spectral pattern（GMSP）can be used to determine the profile of TCRBV gene *** explore the portrait of TCRBV family among peripheral T cell repertoire derived from subjects recovered from acute hepatitis B infection（AHI）.The PBMCs were separated and sorted into CD4and CD8cell *** molecular features of the TCRBV CDR3 motif were determined using GMSP analysis;the TCRBV families were cloned and se-
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