We described two male patients who suffered from azoospermia with pesudodicentric Y *** karyotype of patient A was described as 46,X,psu dic(Y)(pter→q11.2::q11.2→pter).Patient B was a chromosome chimeric individuals...
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We described two male patients who suffered from azoospermia with pesudodicentric Y *** karyotype of patient A was described as 46,X,psu dic(Y)(pter→q11.2::q11.2→pter).Patient B was a chromosome chimeric individuals and his karyotype was described as 45,X/46,X,psu dic(Y)(pter→
Background Several peripheral proteins that might be useful for detecting the presence of ectopic pregnancy (EP) have been evaluated,but none have been proven entirely useful in the *** investigated the presence and t...
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Background Several peripheral proteins that might be useful for detecting the presence of ectopic pregnancy (EP) have been evaluated,but none have been proven entirely useful in the *** investigated the presence and the possible changes in circulating molecules that distinguish between normal intrauterine pregnancy (IUP) and tubal ectopic *** Non-pregnant women during the menstrual cycle,women with IUP,and women with tubal EP after informed *** levels of 17beta-estradiol(E2),progesterone
The low-grade chronic inflammtion is common in PCOS patients,who are characterized by hyperandrogenism or hyperandrogenemia#The clinical researches have proved that the hyperandrogenemia is closely correlated with the...
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The low-grade chronic inflammtion is common in PCOS patients,who are characterized by hyperandrogenism or hyperandrogenemia#The clinical researches have proved that the hyperandrogenemia is closely correlated with the low-grade chronic inflammtion,but the mechanism is unclear# Adipocyte as newly discoved inflammatory cells,When by a certain external stimulation,its inflammatorysignal transduction cascade system activa-
Background Interleukin-24(IL-24) is a novel tumor suppressor gene,which has suppressor activity in a broad spectrum of human cancer *** present study aimed to elucidate the biological function of IL-24 and its recepto...
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Background Interleukin-24(IL-24) is a novel tumor suppressor gene,which has suppressor activity in a broad spectrum of human cancer *** present study aimed to elucidate the biological function of IL-24 and its receptors(IL-20R1,IL-20R2 and IL-22R1) in decidual stromal ceils(DSCs) at human maternal-fetal *** The DSCs behaviors in vitro were verified by MTT and apoptosis assay,***-
Background The orphan nuclear receptor NR4A1(NGFI-B/Nur77/TR3) is a member of the steroid hormone nuclear receptor superfamily with no identified endogenous ***4A1 is an immediately responding gene which induced by mu...
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Background The orphan nuclear receptor NR4A1(NGFI-B/Nur77/TR3) is a member of the steroid hormone nuclear receptor superfamily with no identified endogenous ***4A1 is an immediately responding gene which induced by multiple extracellular ***4A1 plays roles in regulation of cell survival,differentiation and apoptosis,in a cell-type specific *** our previous study,we found that NR4A1 was down-regulated in patients with polycystic ovary syndrome(PCOS).PCOS is characterized by hyperandro-
Objective Epidemiological studies have reported a higher incidence of growth disorders among newborns conceived by in vitro fertilization(IVF),suggesting that IVF may be disruptive to the process of embryonic and feta...
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Objective Epidemiological studies have reported a higher incidence of growth disorders among newborns conceived by in vitro fertilization(IVF),suggesting that IVF may be disruptive to the process of embryonic and fetal ***,the long-term effects of IVF on the growth and molecular mechanisms remain unclear.
Background The incidence of ectopic pregnancy(EP) after assisted reproductive technology(ART) was higher than that in the general *** possible risk factors of EP following ART might include female infertility status e...
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Background The incidence of ectopic pregnancy(EP) after assisted reproductive technology(ART) was higher than that in the general *** possible risk factors of EP following ART might include female infertility status especially tubal distortion,ART procedure,embryo implantation potential and abnormal hormonal ***,the data are still inconsistent to *** hereby investigate the clinical data of our repro-
Background Nometastatic gene 23-H1(NME1,also known as nm23-H1) is a wide-spectrum tumor metastasis suppressor gene that plays an important role in suppressing the invasion and metastasis of tumor cells. The present st...
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Background Nometastatic gene 23-H1(NME1,also known as nm23-H1) is a wide-spectrum tumor metastasis suppressor gene that plays an important role in suppressing the invasion and metastasis of tumor cells. The present study is undertaken to explore the mechanism by which NME1 modulates the biological behavior of ESCs and herein participates in the pathogenesis of *** The ESCs behaviors in vitro were
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