作者:
Ye LiXiao-Yu XuCollege of Pharmaceutical Sciences
Institute of Chinese MedicinePharmacology of Chinese materia medica-the key constructing discipline by the State Administrative Bureau of TCMSouthwest University
AIM:To explore the therapeutic effects of Morinda Officinalis Capsule on osteoporosis in ovariectomized rats. METHODS 6-month-old female Sprague-Dawley rats were induced for Postmenopausal osteoporosis (PMOP) by bil...
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AIM:To explore the therapeutic effects of Morinda Officinalis Capsule on osteoporosis in ovariectomized rats. METHODS 6-month-old female Sprague-Dawley rats were induced for Postmenopausal osteoporosis (PMOP) by bilateral ovariectomy and divided into seven groups as follows:sham-operated group, ovariectomized(OVX) control group,OVX treated with xianlinggubao(XLGB)(270 mg·kg·d),OVX
Objective Fracture healing is a complex process that involves both anabolic and catabolic responses. At the onset of fracture repair there is an initial inflammatory phase followed by the differentiation of mesenchyma...
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Objective Fracture healing is a complex process that involves both anabolic and catabolic responses. At the onset of fracture repair there is an initial inflammatory phase followed by the differentiation of mesenchymal stem cells(MSCs) to form a soft cartilage callus and a hard callus of woven bone,which is ultimately remodeled to generate the original cortical *** repair processes recapitulate
Objective Kyphoplasty is conventionally indicated for osteoporotic vertebral fractures or *** on the surgical principle,the current study was to test the feasibility and therapeutic effect of kyphoplasty for treating ...
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Objective Kyphoplasty is conventionally indicated for osteoporotic vertebral fractures or *** on the surgical principle,the current study was to test the feasibility and therapeutic effect of kyphoplasty for treating severe osteoporotic vertebral fractures which was relative contraindications before. Methods 48 vertebrae of 35 patients(33 females and 2 males with the mean age of 74.2 years.)
Background & Objectives:Vitamin D insufficiency is high prevalence and has been related to low bone mineral density(BMD).However,controversial results have been reported for the relationship between serum 25(OH)D ...
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Background & Objectives:Vitamin D insufficiency is high prevalence and has been related to low bone mineral density(BMD).However,controversial results have been reported for the relationship between serum 25(OH)D levels and *** study is to investigatewhether the serum 25(OH)D are associated with BMD in postmenopausal women living in Guangzhou.
Objective To report a new case on Xanthoma Disseminatum for further understanding of the characterisation of skeletal involvement and treatment of Xanthoma Disseminatum. Method We report a 45-year-old patient presente...
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Objective To report a new case on Xanthoma Disseminatum for further understanding of the characterisation of skeletal involvement and treatment of Xanthoma Disseminatum. Method We report a 45-year-old patient presented with a ten year history of xanthoma around the eye and nose,central diabetes insipidus and T2DM,as well as a four year history of pain in the limbs,loosening of teeth and the recent onset of *** gene CYP27A1 was screened by direct sequencing for
Objective Bone and cartilage defect,most commonly caused by aging and degenerative disease, has become the primary target of tissue engineering due to a lack of effective treatments and limited regenerative *** limite...
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Objective Bone and cartilage defect,most commonly caused by aging and degenerative disease, has become the primary target of tissue engineering due to a lack of effective treatments and limited regenerative *** limited source of autograft necessitates the development of alternative cell *** stem cells with multiple lineage differentiation potentials from various sources can
Objective Previous quantitative studies on bone perfusion by using dynamic contrast enhancement (DCE) MRI have shown a reduced bone marrow perfusion in osteoporotic ***,most frequently used pharmacokinetic models basi...
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Objective Previous quantitative studies on bone perfusion by using dynamic contrast enhancement (DCE) MRI have shown a reduced bone marrow perfusion in osteoporotic ***,most frequently used pharmacokinetic models basically involved the arterial input function(AIF),which was an unstable factor in *** purpose of this study is to characterize bone marrow perfusion properties with a newly established muscle-based model without using AIF.
Objective Recent studies had shown that osteoporotic bone had significantly increased marrow fat compare to the subjects with normal bone mineral density(BMD).However,there was no study to further investigate the mech...
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Objective Recent studies had shown that osteoporotic bone had significantly increased marrow fat compare to the subjects with normal bone mineral density(BMD).However,there was no study to further investigate the mechanical function of the marrow fat in the osteoporotic *** order to figure out the mechanical contribution of marrow fat in bone strength,this study simulated cancellous bone in two extremely conditions:one consisted of trabecular bone only and the other consisted of trabecular bone and
Summary Although obesity and osteoporosis are two important public health problems that greatly impact mortality and morbidity,the effect of fat mass(FM) on bone mineral density(BMD) remains *** study demonstrated tha...
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Summary Although obesity and osteoporosis are two important public health problems that greatly impact mortality and morbidity,the effect of fat mass(FM) on bone mineral density(BMD) remains *** study demonstrated that increased central body fat had an inversely association with total and leg BMD in female but not *** FM and percent body fat(%BF) was positively associated
Introduction Cancer patients experience many sequelae during and after *** many patients now surviving decades after treatment has ceased,it has been important concerns about late-stage sequelae and their effects on o...
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Introduction Cancer patients experience many sequelae during and after *** many patients now surviving decades after treatment has ceased,it has been important concerns about late-stage sequelae and their effects on overall health and quality of life,including bone *** complications from radiation therapy have been described for breast,brain,pelvic,and blood ***,the etiology of nonmaligancy bone complications in cancer patients treated with radiotherapy remains unclear
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