Purpose We administered recombinant interleukin(IL)-4 and recombinant IL-13 locally into the air pouch of mice to improve bone resorption induced by ultra-high-molecular-weight polyethylene (UHMWPE) ***:Air pouches we...
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Purpose We administered recombinant interleukin(IL)-4 and recombinant IL-13 locally into the air pouch of mice to improve bone resorption induced by ultra-high-molecular-weight polyethylene (UHMWPE) ***:Air pouches were established on the back of BALB/c mice,followed by the surgical introduction of a section of calvaria from a syngeneic mouse *** stimulated the bone-
The aim of this study was to perform a head-to-head comparison of efficacy and safety profile between 60 mg denosumab(Den) subcutaneously(SC) per 6 months(Q6M) and 70 mg alendronate(Aln) orally per week(QW) for postme...
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The aim of this study was to perform a head-to-head comparison of efficacy and safety profile between 60 mg denosumab(Den) subcutaneously(SC) per 6 months(Q6M) and 70 mg alendronate(Aln) orally per week(QW) for postmenopausal women with low bone mineral *** searched electronic databases comparing efficacy and safety of Den SC Q6Mand Aln QW in postmenopausal *** primary
Objective To analyse the difference and change rule in T-scores of hip' s and lumbar' s bone mineral density with ageing in 1150 perimenopausal period and senile women in south of Jiangsu Province,and provide ...
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Objective To analyse the difference and change rule in T-scores of hip' s and lumbar' s bone mineral density with ageing in 1150 perimenopausal period and senile women in south of Jiangsu Province,and provide help for clinical application. Methods Using dual energy X-ray absorptiometry,the hip(neck of femur) and lurnbar(L1-L4) bone mineral were measured in 1150 perimenopausal period and senile women aged from 45-75 *** each
Objective To analysis the relation of Enterogenous 5-hydroxytryptamine levels to bone density and biochemical Index of bone metabolism such as serum Procollagen I N-terminal Propeptide(PINP)、β-Crosslaps、Parathyroid...
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Objective To analysis the relation of Enterogenous 5-hydroxytryptamine levels to bone density and biochemical Index of bone metabolism such as serum Procollagen I N-terminal Propeptide(PINP)、β-Crosslaps、Parathyroid Hormone(PTH) and 25-hydroxyvitaminD(25(OH)D) in Human. Methods①We recruited 540 people from an age-stratified random sample of Guangzhou,China *** last the analysis was based on 350 people,all of them were patients of the Gerneral Hospital
Objective Digital clubbing with enlargement of the distal phalanges and overcurvature of the nails frequently occurs as a secondary feature of chronic hypoxia in bronchopulmonary or cardiovascular disease and systemic...
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Objective Digital clubbing with enlargement of the distal phalanges and overcurvature of the nails frequently occurs as a secondary feature of chronic hypoxia in bronchopulmonary or cardiovascular disease and systemic inflammatory or neoplastic processes,as well as in less common primary hypertrophic osteoarthropathy(PHO),whose genetic decipherment provides a better understanding of those more common secondary *** in SLCO2A1 gene,encoding homo sapiens solute carrier
Objective To investigate the distribution of A986S and R990Gpolymorphisms of CASR gene in Chinese population,and their relationship with the risk and clinical phenotypes of primary hyperparathyroidism(PHPT) in Chinese...
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Objective To investigate the distribution of A986S and R990Gpolymorphisms of CASR gene in Chinese population,and their relationship with the risk and clinical phenotypes of primary hyperparathyroidism(PHPT) in Chinese population. Patients and methods 164 consecutive Chinese Han PHPT patients(M/F:51/113) and 230 healthy controls(M/F:50/180) were *** clinical parameters in PHPT patients including biochemical
Objective Acrodysostosis(ACRDYS) is a rare skeletal dysplasia,some of which have multiple hormone ***1A gene,which encodes the typeⅠ-alpha regulatory subunits of cAMP-dependent protein kinase,has been found to be ass...
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Objective Acrodysostosis(ACRDYS) is a rare skeletal dysplasia,some of which have multiple hormone ***1A gene,which encodes the typeⅠ-alpha regulatory subunits of cAMP-dependent protein kinase,has been found to be associated with *** objective was to investigate the clinical manifestation and genetic background of a Chinese girl of ACRDYS with multiple hormone resistance.
Objective Bone quality has been an important research topic on *** purpose of this study was to evaluate trabecular micro- and nano-scale structural and mechanical properties and 3D- and 2D-BMD in ovariectomized rats....
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Objective Bone quality has been an important research topic on *** purpose of this study was to evaluate trabecular micro- and nano-scale structural and mechanical properties and 3D- and 2D-BMD in ovariectomized rats. Methods Twenty 10-month-old female Sprague-Dawley rats were randomly divided into bilateral ovariectomy(OVX) and sham-operated(SHAM) *** 15 weeks postoperation,DXA was used
Objective Salvianolic acid B(Sal B) is water-soluble component from Danshen(a Chinese medicinal herb),has been shown to induce bone growth in in vitro and in vivo ***,there are no studies evaluating the effect of Sal ...
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Objective Salvianolic acid B(Sal B) is water-soluble component from Danshen(a Chinese medicinal herb),has been shown to induce bone growth in in vitro and in vivo ***,there are no studies evaluating the effect of Sal B on human bone marrow derived mesenchymal stem cells(hBMSCs).Thus, the aim of this study was to investigate osteogenesis induced by Sal B on hBMSCs.
Objective To study the inconsistency of tested parts being chosen in clinic diagnosis,and the changes or regulations in T-scores of hip and lumbar by DXA in different aged people by retrospective analyses of the local...
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Objective To study the inconsistency of tested parts being chosen in clinic diagnosis,and the changes or regulations in T-scores of hip and lumbar by DXA in different aged people by retrospective analyses of the local physical examined people in Suzhou. MethodsUsing dual energy X-ray absorptiometry,the neck of femur and lumbar(L1-L4) bone mineral density was measured in 3662 men and women over 45 years old,and this study was standardized by equations and analyzed by statistics. Results①35.8%women and 39.5%men chose only single part to test by DXA,and in different
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