目的探讨Toll样受体4（Toll like receptor 4,TLR4）单核苷酸多态性（SNPs）与中国东南方汉族人群哮喘发病危险性和哮喘相关表型的关系。方法在HapMap上挑选TLR4的全部标签SNPs（tagging SNPs）rs1927914、rs10983755、rs11536879、rs19...
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目的探讨Toll样受体4（Toll like receptor 4,TLR4）单核苷酸多态性（SNPs）与中国东南方汉族人群哮喘发病危险性和哮喘相关表型的关系。方法在HapMap上挑选TLR4的全部标签SNPs（tagging SNPs）rs1927914、rs10983755、rs11536879、rs1927907。连续性招募哮喘患者318人,正常对照352人。采用多重PCR结合标签阵列单碱基延伸技术和Taqman法进行基因分型。通过病例—对照（case-control）和病例—病例（case-case）研究分析这些位点与哮喘及哮喘表型的关系。病例组和对照组的一般资料间比较采用t检验x检验。对照
Clinical and experimental evidence suggests that genetic variations may play an important role in the development of acute lung injury(ALI).Lipopolysaccharide(LPS)-induced ALI models has been widely applied for pathop...
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Clinical and experimental evidence suggests that genetic variations may play an important role in the development of acute lung injury(ALI).Lipopolysaccharide(LPS)-induced ALI models has been widely applied for pathophysiological and pharmacological *** order to understand the variation of acute pulmonary reactions between mouse strains and find the
Background:T cells play an important role in orchestrating allergic asthma by producing various cytokines,but little information is available on the phenotype of cytokines-producing T cells,especially CD8T and
Background:T cells play an important role in orchestrating allergic asthma by producing various cytokines,but little information is available on the phenotype of cytokines-producing T cells,especially CD8T and
Asthma is characterized by airway inflammation,mucus overproduction,airway hyperreactivity and peribronchial *** has been shown to be increased in airway epithelium of ***,the role of intelectin in the pathogenesis of...
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Asthma is characterized by airway inflammation,mucus overproduction,airway hyperreactivity and peribronchial *** has been shown to be increased in airway epithelium of ***,the role of intelectin in the pathogenesis of asthma is *** epithelial cells can secrete chemokines such as monocyte chemotactic
To fulfill its commitment to a successful 2008 Olympic and Paralympic Games,the Chinese government made unprecedented efforts to improve the air quality in Beijing,one of world' s worst polluted *** July 1 and Sep...
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To fulfill its commitment to a successful 2008 Olympic and Paralympic Games,the Chinese government made unprecedented efforts to improve the air quality in Beijing,one of world' s worst polluted *** July 1 and September 20,2008,temporary vehicle restrictions were implemented:the"yellow-labeled"trucks(trucks that failed emission standards) were
Introduction:Venous thromboembolism(VTE) is the third most common cardiovascular disease after acute ischemic cardiovascular syndromes and stroke in the United ***,data have showed that the Asians/Pacific Islanders ha...
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Introduction:Venous thromboembolism(VTE) is the third most common cardiovascular disease after acute ischemic cardiovascular syndromes and stroke in the United ***,data have showed that the Asians/Pacific Islanders have a 70%lower prevalence of VTE and the similar incidence of VTE among Asians has been reported in Hong Kong and *** fact,there has no sufficient evidence to support that the Asians being less susceptible to PE than other ethics.
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