Purpose Circulating b2-glycoprotein-I-oxidized low density lipoprotein（b-GPI- ox-LDL） complexes have been found in patients with systemic lupus erythematosus（SLE）,rheumatoid arthritis（RA） and other autoimmune di...
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Purpose Circulating b2-glycoprotein-I-oxidized low density lipoprotein（b-GPI- ox-LDL） complexes have been found in patients with systemic lupus erythematosus（SLE）,rheumatoid arthritis（RA） and other autoimmune diseases as a contributor to the development of autoimmune-mediated *** recent study found the existence of complexes ofβ-glycoprotein I（β-GPI） with lipoprotein（a）[Lp（a）],a key molecule in the
Objection:To investigate the prevalence of anti-CCD IgE in Beijing medical staffs and study the contribution of anti-CCD IgE as a cause of clinically irrelevant IgE for several allergens. Methods:A survey of 1091 medi...
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Objection:To investigate the prevalence of anti-CCD IgE in Beijing medical staffs and study the contribution of anti-CCD IgE as a cause of clinically irrelevant IgE for several allergens. Methods:A survey of 1091 medical staffs(299 men,792 women,average age 42) in Beijing has been conducted by fulfilling questionnaire on *** were analyzed on the basis of the symptoms and allergen provided by the
Background To evaluatethe degree ofhepatocyte injury in hepatitis B patients,with accurateplasma DNA quantification,and to study its clinical application in differentiation of all kinds of hepatitis B by comparison of...
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Background To evaluatethe degree ofhepatocyte injury in hepatitis B patients,with accurateplasma DNA quantification,and to study its clinical application in differentiation of all kinds of hepatitis B by comparison of alanine aminotransferase(ALT). Methods Peripheral blood samples were collected from a cohort of 199 patients with hepatitis B which were divided into four groups (severe hepatitis,acute hepatitis,chronic hepatitis B and liver cirrhosis).Circulating DNA
@@ To investigate the serum blirubin levels inSLE patients and explore independent impactfactors of the varied serum bilirubin levels and theassociations with some clinical and laboratorycharacteristics in SLE patient...
@@ To investigate the serum blirubin levels inSLE patients and explore independent impactfactors of the varied serum bilirubin levels and theassociations with some clinical and laboratorycharacteristics in SLE patients with or without *** There were 1 98 SLE patients in thisstudy，of whom 7 cases with tobacco smoking oralcohol intake were excluded，while 1 54 *** healthy volunteers with no histories *** diseases and other autoimmune orinflammatory diseases were randomly recruitedinto this study.
OBJECTIVE A previous meta-analysis was performed to assess the association between variations in NRAMP1 and tuberculosis(TB) risk, but its limitations were that it did not report genotype comparative results,and not d...
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OBJECTIVE A previous meta-analysis was performed to assess the association between variations in NRAMP1 and tuberculosis(TB) risk, but its limitations were that it did not report genotype comparative results,and not discuss the association with extra-pulmonary TB(EPTB).So, we carried out an updated meta-analysis to further investigate the association between NRAMP1 and TB susceptibility.
Objectives Increasing evidence suggests that patients with gout have a high incidence of atherosclerotic coronary heart *** serum paraoxonase(PON) activity is thought to be a risk factor for the development of *** con...
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Objectives Increasing evidence suggests that patients with gout have a high incidence of atherosclerotic coronary heart *** serum paraoxonase(PON) activity is thought to be a risk factor for the development of *** connection between PON1 activity and oxidative stress measures and atherosclerosis in gout has not been *** present study was designed to
Introduction Uterine cervical cancer(UCC) remains the second most frequent malignancy in women *** infection alone is not sufficient to induce malignant changes,suggesting additional host genetic factors may be involv...
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Introduction Uterine cervical cancer(UCC) remains the second most frequent malignancy in women *** infection alone is not sufficient to induce malignant changes,suggesting additional host genetic factors may be involved in the development and progression of UCC. B-cell-specific Moloney murine leukemia virus integration site 1(Bmi-1) is a member of polycomb group,which participates in axial patterning,
Background Diabetic nephropathy(DN) is the leading cause of chronic kidney disease in patients starting renal replacement *** intervention and consequent therapy may prevent or at least delay the development of end-st...
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Background Diabetic nephropathy(DN) is the leading cause of chronic kidney disease in patients starting renal replacement *** intervention and consequent therapy may prevent or at least delay the development of end-stage renal *** aim of this study was to establish a proteomic method for identification of DN-related biomarkers in urine that may serve as diagnostic
Objective To primarily explore CDR3 spectratyping and molecular features of TCR |3 chain in the peripheral blood and tissue of patients with colorectal carcinoma with RQ-PCR with DNA melting curve technique. MethodsBl...
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Objective To primarily explore CDR3 spectratyping and molecular features of TCR |3 chain in the peripheral blood and tissue of patients with colorectal carcinoma with RQ-PCR with DNA melting curve technique. MethodsBlood and tissue samples were collected from seven patients with colorectal carcinoma (CRC),while blood samples were also collected from two healthy controls as *** the
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