Objectives:To experimently investigate the role of peroxisome proliferator - activated receptors(PPARs) in NAFLD/NASH of SD rats with insulin resistance,and the possible efficacy by way of using their agonists. Method...
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Objectives:To experimently investigate the role of peroxisome proliferator - activated receptors(PPARs) in NAFLD/NASH of SD rats with insulin resistance,and the possible efficacy by way of using their agonists. Methods:Sixty male SD rats were randomly divided into 4 groups:normal control group(NC n = 20),model
Objectives:To investigate the association of thiopurine methyltransferase(TPMT) polymorphisms and activity with azathioprine(AZA) -related adverse events and clinical efficacy in Chinese Han patients with inflammatory...
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Objectives:To investigate the association of thiopurine methyltransferase(TPMT) polymorphisms and activity with azathioprine(AZA) -related adverse events and clinical efficacy in Chinese Han patients with inflammatory bowel disease(IBD).Methods:Fifty-two Han IBD patients treated with AZA were assessed for
Objectives:We validated International Autoimmune Hepatitis Group(IAIHG) revised the diagnostic scoring system of autoimmune hepatitis(AIH) ? and ? simplified scoring system in Chinese patients with AIH or other liver ...
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Objectives:We validated International Autoimmune Hepatitis Group(IAIHG) revised the diagnostic scoring system of autoimmune hepatitis(AIH) ? and ? simplified scoring system in Chinese patients with AIH or other liver ***:Diagnostic scores were determined using the original(1999 system) and the sim-
Objective:Postinfectious irritable bowel syndrome(PI - IBS) is a newly discovered subgroup of IBS, which occupies lots of gastroenterology *** mucosal immune activation in PI - IBS has been cer-
Objective:Postinfectious irritable bowel syndrome(PI - IBS) is a newly discovered subgroup of IBS, which occupies lots of gastroenterology *** mucosal immune activation in PI - IBS has been cer-
Objectives:To determine the prevalence,characteristics and risk factors of erosive esophagitis(EE) and Barrett's esophagus(BE) in a Chinese adult population without gastro- esophageal reflux symptoms(GERS) Methods...
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Objectives:To determine the prevalence,characteristics and risk factors of erosive esophagitis(EE) and Barrett's esophagus(BE) in a Chinese adult population without gastro- esophageal reflux symptoms(GERS) Methods:Consecutive subjects aged between 18 and 75 years old,who underwent routine upper endoscopy as
Objective:It has been demonstrated that acute and chronic stress could induce dilated intercellular spaces (DIS) and increase esophageal mucosa permeability in rats,which is accompanied by infiltration of mast cells. ...
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Objective:It has been demonstrated that acute and chronic stress could induce dilated intercellular spaces (DIS) and increase esophageal mucosa permeability in rats,which is accompanied by infiltration of mast cells. In order to identify the role of mast cell in those process,we investigated the influence of chronic restraint stress
Objectives:To demonstrate the relationship between prolonged alcohol intake and chronic ***:Wistar rats were fed diet containing 25%concentration(vol/vol) of ethanol for 6 ***(CCK) was quantified by *** was used to de...
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Objectives:To demonstrate the relationship between prolonged alcohol intake and chronic ***:Wistar rats were fed diet containing 25%concentration(vol/vol) of ethanol for 6 ***(CCK) was quantified by *** was used to detect
Objective:To create a tumor specific lentivirus that expresses GFP under optimized hTERT promoter. Combined with whole -body optical imaging equipment,this lentivirus was evaluated for application in realtime diagnosi...
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Objective:To create a tumor specific lentivirus that expresses GFP under optimized hTERT promoter. Combined with whole -body optical imaging equipment,this lentivirus was evaluated for application in realtime diagnosis of early stage tumor,and noninvasive study of tumor ***:Core hTERT promoter
Objectives:To construct the recombinant plasmid carrying fusion suicide gene CDglyTK and RNA interference eukaryotic expressing vector of targeting to STAT3,and to investigate the effect of double suicide gene combine...
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Objectives:To construct the recombinant plasmid carrying fusion suicide gene CDglyTK and RNA interference eukaryotic expressing vector of targeting to STAT3,and to investigate the effect of double suicide gene combined with RNAi targeting to STAT3 on HCT116 and HUVEC ***:The CD and TK were cloned by polymerase chain reaction(PCR),and fusion gene CDglyTK was inserted into plasmid pEGFP after DNA se-
Objectives:The present study is to explore major manifestations of maldigestion after abstinence and the mechanism behind ***:A clinical survey of 124 male drinkers was conducted in order to demonstrate the major dysp...
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Objectives:The present study is to explore major manifestations of maldigestion after abstinence and the mechanism behind ***:A clinical survey of 124 male drinkers was conducted in order to demonstrate the major dyspeptic symptoms associated with alcohol *** addition,forty -eight healthy male Wistar
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