Objective The optimal timing of stabilization in patients with traumatic thoracolumbar fractures remains *** is currently a lack of consensus on the timing of surgical stabilization,which is limited by the reality tha...
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Objective The optimal timing of stabilization in patients with traumatic thoracolumbar fractures remains *** is currently a lack of consensus on the timing of surgical stabilization,which is limited by the reality that a randomized controlled trial to evaluate early versus late stabilization is difficult
Purpose AngiotensinⅡ(AngⅡ) significantly induced the expression of receptor activator of NF-κB ligand(RANKL) in osteoblasts,leading to the formation of *** chemoattractant protein-1(MCP-1) is a potent stimulator of...
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Purpose AngiotensinⅡ(AngⅡ) significantly induced the expression of receptor activator of NF-κB ligand(RANKL) in osteoblasts,leading to the formation of *** chemoattractant protein-1(MCP-1) is a potent stimulator of the formation of osteoclasts as *** secretion of
Background:Iguratimod(T-614) is a potent anti-inflammatory agent for rheumatoid arthritis. However,the direct effects of iguratimod and its mechanisms on osteoclast differentiation in vitro and vivo remain unknown. Ob...
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Background:Iguratimod(T-614) is a potent anti-inflammatory agent for rheumatoid arthritis. However,the direct effects of iguratimod and its mechanisms on osteoclast differentiation in vitro and vivo remain unknown. Objectives:In this study,we examined the direct effects of iguratimod on osteoclastogenesis in
Objective Although cadmium and fluoride may both have adverse effects on bone,most studies focus on a single *** this study,we investigated the effects of cadmium and fluoride on bone at a relative low level. Material...
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Objective Although cadmium and fluoride may both have adverse effects on bone,most studies focus on a single *** this study,we investigated the effects of cadmium and fluoride on bone at a relative low level. Materials and Methods Sprague-Dawley male rats were assigned randomly into 4 groups which
Purpose Glucocorticoids(GCs) treatment frequently causes osteoporosis,but currently the precise mechanism in the pathogenesis of glucocorticoid-induced osteoporosis(GIOP) is still not fully elucidated. The purpose of ...
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Purpose Glucocorticoids(GCs) treatment frequently causes osteoporosis,but currently the precise mechanism in the pathogenesis of glucocorticoid-induced osteoporosis(GIOP) is still not fully elucidated. The purpose of the study was to investigate the roles of the local renin-angiotensin system(RAS) of bone
Purpose Angiotensin type 1 receptors(AT1 receptors) blocker and angiotensin converting enzyme inhibitor(ACEI) were shown to improve osteoporotic bone in ovariectomized ***,the explicit role of local bone renin-angiote...
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Purpose Angiotensin type 1 receptors(AT1 receptors) blocker and angiotensin converting enzyme inhibitor(ACEI) were shown to improve osteoporotic bone in ovariectomized ***,the explicit role of local bone renin-angiotensin system(RAS) in postmenopausal osteoporosis was not investigated.
Quantitative computed tomography(QCT),which was largely invented at the University of California San Francisco(UCSF) in the late 1970's and early 80's,has several advantages over dual-energy X-ray absorptiomet...
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Quantitative computed tomography(QCT),which was largely invented at the University of California San Francisco(UCSF) in the late 1970's and early 80's,has several advantages over dual-energy X-ray absorptiometry(DXA) for the measurement of bone mineral density(BMD).QCT is used to reliably and sensitively measure three-dimensional bone mineral density in the spine or hip,and to separately analyze
Objective To investigate the effects of transplantation of allogenic adipose-derived stem cells (ADSCs) on the bone metabolic markers and bone histomorphometry in ovariectomized(ovx) female rats. METHODS Thirty female...
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Objective To investigate the effects of transplantation of allogenic adipose-derived stem cells (ADSCs) on the bone metabolic markers and bone histomorphometry in ovariectomized(ovx) female rats. METHODS Thirty female nonpregnant Wistar rats were randomly divided into two groups:ovx(
Objective To explore the treatment of 99Tc-MDP on rats with osteoporosis induced by dexamethasone. Methods 30 of the 12-week-old female Wistar rats were randomly divided into three groups,control group,model group and...
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Objective To explore the treatment of 99Tc-MDP on rats with osteoporosis induced by dexamethasone. Methods 30 of the 12-week-old female Wistar rats were randomly divided into three groups,control group,model group and treatment group,and there were 10 rats in each *** group and treatment
Purpose The aim of the present study was to investigate the effects of panax notoginseng saponins(PNS)which inhibits the apoptosis of neuron on bone loss in steroid-induced osteoporosis in rats and its impact on the a...
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Purpose The aim of the present study was to investigate the effects of panax notoginseng saponins(PNS)which inhibits the apoptosis of neuron on bone loss in steroid-induced osteoporosis in rats and its impact on the apoptosis of cultured primary osteoblasts. Methods 30 adult Sprague-Dawley rats were randomly divided into the following groups with 10
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