Purpose Angiotensin type 1 receptors(AT1 receptors) blocker and angiotensin converting enzyme inhibitor(ACEI) were shown to improve osteoporotic bone in ovariectomized ***,the explicit role of local bone renin-angiote...
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Purpose Angiotensin type 1 receptors(AT1 receptors) blocker and angiotensin converting enzyme inhibitor(ACEI) were shown to improve osteoporotic bone in ovariectomized ***,the explicit role of local bone renin-angiotensin system(RAS) in postmenopausal osteoporosis was not investigated.
Purpose AngiotensinⅡ(AngⅡ) significantly induced the expression of receptor activator of NF-κB ligand(RANKL) in osteoblasts,leading to the formation of *** chemoattractant protein-1(MCP-1) is a potent stimulator of...
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Purpose AngiotensinⅡ(AngⅡ) significantly induced the expression of receptor activator of NF-κB ligand(RANKL) in osteoblasts,leading to the formation of *** chemoattractant protein-1(MCP-1) is a potent stimulator of the formation of osteoclasts as *** secretion of
Objective To investigate the effects of transplantation of allogenic adipose-derived stem cells (ADSCs) on the bone metabolic markers and bone histomorphometry in ovariectomized(ovx) female rats. METHODS Thirty female...
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Objective To investigate the effects of transplantation of allogenic adipose-derived stem cells (ADSCs) on the bone metabolic markers and bone histomorphometry in ovariectomized(ovx) female rats. METHODS Thirty female nonpregnant Wistar rats were randomly divided into two groups:ovx(
Objective Although cadmium and fluoride may both have adverse effects on bone,most studies focus on a single *** this study,we investigated the effects of cadmium and fluoride on bone at a relative low level. Material...
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Objective Although cadmium and fluoride may both have adverse effects on bone,most studies focus on a single *** this study,we investigated the effects of cadmium and fluoride on bone at a relative low level. Materials and Methods Sprague-Dawley male rats were assigned randomly into 4 groups which
Purpose Glucocorticoids(GCs) treatment frequently causes osteoporosis,but currently the precise mechanism in the pathogenesis of glucocorticoid-induced osteoporosis(GIOP) is still not fully elucidated. The purpose of ...
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Purpose Glucocorticoids(GCs) treatment frequently causes osteoporosis,but currently the precise mechanism in the pathogenesis of glucocorticoid-induced osteoporosis(GIOP) is still not fully elucidated. The purpose of the study was to investigate the roles of the local renin-angiotensin system(RAS) of bone
Objective To explore the treatment of 99Tc-MDP on rats with osteoporosis induced by dexamethasone. Methods 30 of the 12-week-old female Wistar rats were randomly divided into three groups,control group,model group and...
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Objective To explore the treatment of 99Tc-MDP on rats with osteoporosis induced by dexamethasone. Methods 30 of the 12-week-old female Wistar rats were randomly divided into three groups,control group,model group and treatment group,and there were 10 rats in each *** group and treatment
Purpose The aim of the present study was to investigate the effects of panax notoginseng saponins(PNS)which inhibits the apoptosis of neuron on bone loss in steroid-induced osteoporosis in rats and its impact on the a...
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Purpose The aim of the present study was to investigate the effects of panax notoginseng saponins(PNS)which inhibits the apoptosis of neuron on bone loss in steroid-induced osteoporosis in rats and its impact on the apoptosis of cultured primary osteoblasts. Methods 30 adult Sprague-Dawley rats were randomly divided into the following groups with 10
Objective Fracture healing is a complex process that involves both anabolic and catabolic responses. At the onset of fracture repair there is an initial inflammatory phase followed by the differentiation of mesenchyma...
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Objective Fracture healing is a complex process that involves both anabolic and catabolic responses. At the onset of fracture repair there is an initial inflammatory phase followed by the differentiation of mesenchymal stem cells(MSCs) to form a soft cartilage callus and a hard callus of woven bone,which is ultimately remodeled to generate the original cortical bone *** repair processes
Objective To analyse the difference and change rule in T-scores of hip's and lumbar's bone mineral density with ageing in 1150perimenopausal period and senile women in south of Jiangsu Province,and provide hel...
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Objective To analyse the difference and change rule in T-scores of hip's and lumbar's bone mineral density with ageing in 1150perimenopausal period and senile women in south of Jiangsu Province,and provide help for clinical application. Methods Using dual energy X-ray absorptiometry,the hip(neck of femur) and lumbar(L1-L4) bone
Purpose To evaluate the curative effect of hip arthroplasty with intertrochanteric reconstruction technique for the treatment of intertrochanteric fractures in elderly patients of osteoporosis. Methods 30 senile patie...
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Purpose To evaluate the curative effect of hip arthroplasty with intertrochanteric reconstruction technique for the treatment of intertrochanteric fractures in elderly patients of osteoporosis. Methods 30 senile patients of osteoporosis(32hips) with intertrochanteric fracture between May 2008 and May 2010 were admitted in our *** patients admitted in this study were diagnosed as
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