Purpose Spinal cord injury (SCI) results in reduced locomotor function and negatively affects the muscle strength. This study aimed to conduct a pilot study of repetitive transcranial magnetic stimulation(rTMS) combin...
Purpose Spinal cord injury (SCI) results in reduced locomotor function and negatively affects the muscle strength. This study aimed to conduct a pilot study of repetitive transcranial magnetic stimulation(rTMS) combing with Body-Weight-Supported Treadmill Training(BWSTT) in patients with incomplete SCI, and to assess its safety. The patients were assessed using electrophysiological, clinical and functional measures before and after treatment and during a 3-week follow-up period. We also use functional magnetic resonance imaging(fMRI) to study if an association exists between changes in cortical sensorimotor representations within cortical sensorimotor areas and recovery of movement after the intervention.
@@ OBJECTIVE (1)To screen the distinguishing patterns of protein and gene expression of femoral vein vascular tissue at different status (status of pre-thromgenesis, thrombogenesis peak, and non-thrombogenesis), by es...
@@ OBJECTIVE (1)To screen the distinguishing patterns of protein and gene expression of femoral vein vascular tissue at different status (status of pre-thromgenesis, thrombogenesis peak, and non-thrombogenesis), by establishing a rat traumatic deep vein thrombosis model. (2) To formulate uniform clinical standards for diagnosis、inclusion and exclusion in patients, collect DVT patient's venous blood, and screen differentially proteins expression in 2 groups (the human thrombosis group/non-thrombosis group). (3) Comparing the expression of the protein and gene in rats' venous vascular tissue and in human's venous blood, in order to find out characteristic protein expression (including IL-1|3, IL-6, A2M, Cathepsin D and Cathepsin G) in rats' vein vascular tissue, which were highly relevant to the endothelium and platelet, (4) Using ELISA to further identify the different changes of expression about these important proteins in human blood, and explore the potential role of these proteins in the process of endothelial cell injury, platelet activation, inflammatory factor activation, regulation of the interaction mechanism, and the function of promoting thrombosis.
目的：使用功能磁共振成像(functional magnetic resonanceimaging，fMRI)技术对脑梗死后重组运动皮质进行定位，并确定促进运动功能康复的关键脑区，为干预治疗提供影像学依据。方法：选择急性脑梗死患者20人作为实验组，健康受试者10...
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目的：使用功能磁共振成像(functional magnetic resonanceimaging，fMRI)技术对脑梗死后重组运动皮质进行定位，并确定促进运动功能康复的关键脑区，为干预治疗提供影像学依据。方法：选择急性脑梗死患者20人作为实验组，健康受试者10人，作为正常对照组，对照组进行右或左手同样运动任务的fMRI检查。采用MATALB平台的SPM5软件进行预处理，生成脑激活区统计参数图，比较两组间脑激活区的异同，找出可能影响患手运动功能的关键脑区。结果：10例正常受试者，右或左手运动时激活脑区为对侧初级运动皮质(Primazy motor cortex，M1)区和同侧小脑;实验组脑梗塞患者，右或左手(即患手)运动时激活脑区为双侧大脑半球的M1区、双侧辅助运动皮质(supplementary motorcortex，SMC)、后顶叶皮层(posterior parietal cortex，PPC)、前额叶皮层(prefrontal cortex，PFC)区和双侧小脑。脑梗死后健侧M1区为重组运动皮质的关健脑区(P=0.005)。
@@ The World Health Organisation (WHO) and the World Bank have launched the World Report on Disability (1) by in the United Nations Headquarters in New York on June 9, 2011. It refers to the UN-Convention of the Right...
@@ The World Health Organisation (WHO) and the World Bank have launched the World Report on Disability (1) by in the United Nations Headquarters in New York on June 9, 2011. It refers to the UN-Convention of the Rights of Persons with Disabilities (2) and slates - based on statistical data-that 1 billion people in the world experience significant disabilities. This corresponds to about 15％ of the world's population and is higher than WHO has estimated previously (1). One of the chapters of the report highlights the significance of rehabilitation as aset of measures to improve functioning and enables participation. This includes prevention of the loss of function, slowing the rate of loss of function, improvement or restoration of functions, compensation for lost function, and maintenance of current function The WRD concludes that rehabilitation needs team-integrated action including Rehabilitation Medicine, therapies as well as assistive technologies. A special focus of the WRD lies in the description of unmet needs in rehabilitation and in barriers to rehabilitation from this specific action to improve rehabilitation services is addressed including addressing barriers to rehabilitation, reforming policies, laws, and delivery systems, developing funding mechanism for rehabilitation, increasing human resources for rehabilitation, expanding and decentralizing service delivery, increasing the use and affordability of technology, and expanding research and evidence practice. Thus there are many fields PRM can contribute to the necessary action to fight against disability and barriers for inclusion of persons with disabilities, e.g.
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