Purpose To investigate the risk factors and prognostic value of trigeminal nerve involvement in nasopharyngeal carcinoma (NPC) *** and Methods MR images of 105 consecutive NPC patients were prospectively *** cases wer...
Purpose To investigate the risk factors and prognostic value of trigeminal nerve involvement in nasopharyngeal carcinoma (NPC) *** and Methods MR images of 105 consecutive NPC patients were prospectively *** cases were treated with definitive intensity-modulated radiotherapy and 94.3% of them received platinum-based *** risk factors and prognostic value of trigeminal nerve involvement were investigated.
Purpose Using the matched-pair approach for comparison of surgery after neoadjuvant chemoradiotherapy (NCT), surgery alone and definitive chemoradiotherapy (CCRT) with similar clinical stage and other baseline charact...
Purpose Using the matched-pair approach for comparison of surgery after neoadjuvant chemoradiotherapy (NCT), surgery alone and definitive chemoradiotherapy (CCRT) with similar clinical stage and other baseline characteristics, this study aimed to assist physicians for determining treatment options for patients with localized advanced thoracic esophageal squamous cell carcinoma (ESCC).
Background The purpose of this study was to evaluate the influence of progonistic nutritional index (PNI) and weight loss on metastasis and long-term mortality in patients with *** 694 newly diagnosed patients with no...
Background The purpose of this study was to evaluate the influence of progonistic nutritional index (PNI) and weight loss on metastasis and long-term mortality in patients with *** 694 newly diagnosed patients with non-disseminated, biopsy-proven NPC were retrospectively *** analysis was used to evaluate the predictive value of PNI and weight loss.
Background The purpose of this study was to create a prognostic model for distant metastasis in patients with locoregionally advanced NPC who accept concurrent chemotherapy combined with intensity-modulated radiothera...
Background The purpose of this study was to create a prognostic model for distant metastasis in patients with locoregionally advanced NPC who accept concurrent chemotherapy combined with intensity-modulated radiotherapy (CCRT) to identify high-risk patients who may benefit from neoadjuvant chemotherapy (NACT).
OBJECTIVE This study sought to evaluate the association between 9 polymorphisms located in 6 genes related to the DNA repair pathway (ERCC1, ERCC2, APEX1 and XRCC1), oxidative stress response (MPO) and vascular endoth...
OBJECTIVE This study sought to evaluate the association between 9 polymorphisms located in 6 genes related to the DNA repair pathway (ERCC1, ERCC2, APEX1 and XRCC1), oxidative stress response (MPO) and vascular endothelial growth factor (VEGFA) and the risk of severe acute oral mucositis (AOM) in nasopharyngeal carcinoma (NPC) patients.
Purpose to determine the clinical and biological prognostic factors for locoregional recurrence in patients with thoracic esophageal squamous cell carcinoma (ESCC) that received radical two-field lymph node resection ...
Purpose to determine the clinical and biological prognostic factors for locoregional recurrence in patients with thoracic esophageal squamous cell carcinoma (ESCC) that received radical two-field lymph node resection (2FLD).Methods A total of 462 patients, who were diagnosed with thoracic ESCC, underwent radical esophagectomy between March 2001 and May 2010 at the Sun Yat-Sen University Cancer Center.
Purpose Stereotactic ablative radiotherapy (SABR)directly kills lung cancer cells and stimulates tumor antigen release, the immune response to which can be augmented further by systemic immune-modulating ***, local re...
Purpose Stereotactic ablative radiotherapy (SABR)directly kills lung cancer cells and stimulates tumor antigen release, the immune response to which can be augmented further by systemic immune-modulating ***, local relapses often occur after RT alone, indicating that inhibitory mechanisms may limit the anti-tumor immune *** hypothesized that delivery of anti-PD-L1 checkpoint blockade immunotherapy, following SABRmight lead to prolonged antitumor immunity by promoting the destruction of immunosuppressive myeloid cells through a cytotoxic T cell-dependent mechanism.
Purpose While 3 dimensional conformal radiotherapy (3DCRT) is still widely used for the treatment of esophageal cancer (EC), Intensity Modulated Radiation Therapy (IMRT) improves dose sparing to surrounding organs, pa...
Purpose While 3 dimensional conformal radiotherapy (3DCRT) is still widely used for the treatment of esophageal cancer (EC), Intensity Modulated Radiation Therapy (IMRT) improves dose sparing to surrounding organs, particularly the heart and lung, with some evidence in the literature showing clinical benefit to *** we report our cumulative clinical experience with the use of IMRT for EC.
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