*** study the plasma pharmacokinetics and accumulation of recombinant human parathyroid hormone（1-84）in rhesus monkeys,and the tissue distribution and excretion profiles of I-rhPTH（1-84）in rats. *** concentration ...
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*** study the plasma pharmacokinetics and accumulation of recombinant human parathyroid hormone（1-84）in rhesus monkeys,and the tissue distribution and excretion profiles of I-rhPTH（1-84）in rats. *** concentration of rhPTH（1-84）in plasma sample was determined by an enzyme immunoassay method after subcutaneous and intravenous bolus *** tissue distribution and urinary,fecal and biliary excretion patterns of I-rhPTH （1-84）were investigated by TCA precipitation method.
Objective:Wemer' s syndrome is a rare,autosomal recessive *** clinical features of the syndrome is characterized by short stature,bird-like appearance of the face,and early onset of aging processes such as graying...
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Objective:Wemer' s syndrome is a rare,autosomal recessive *** clinical features of the syndrome is characterized by short stature,bird-like appearance of the face,and early onset of aging processes such as graying of hair and osteoporosis. Here,we reported the case of a patient presented firstly with diabetes mellitus and lipodystrophy harboring the novel heterozygous mutation in LMNA gene.
Pancreatic islets implanted heterotopically become poorly revascularized following *** aim of this study was to investigate the effects of combination treatment of intrapancreatic islet transplantation,bone marrow mes...
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Pancreatic islets implanted heterotopically become poorly revascularized following *** aim of this study was to investigate the effects of combination treatment of intrapancreatic islet transplantation,bone marrow mesenchymal stem cells(MSC) transplantation and islet neogenesis-associated
Methimazole(MMI) provokes a variety of adverse effects during the treatment for Graves' *** most frequently reported manifestations are pruritus,rubefaction,erythra and fever,but MMI-induced acute pancreatitis is ...
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Methimazole(MMI) provokes a variety of adverse effects during the treatment for Graves' *** most frequently reported manifestations are pruritus,rubefaction,erythra and fever,but MMI-induced acute pancreatitis is rarely *** to now,Taguchi in Japan(Taguchi et al.1999) and Su in China (Su and Zou,2008) had reported one case,***, we reported a patient with Graves' disease developed acute pancreatitis induced by *** addition,the possible mechanisms involving in MMI-induced acute pancreatitis were discussed in the report.
Background:To evaluate the obese epidemic and obesityrelated risk factors in children and adolescents. Methods:A population-based cross-sectional study was conducted in Shantou,China,in which a total of 5662 students ...
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Background:To evaluate the obese epidemic and obesityrelated risk factors in children and adolescents. Methods:A population-based cross-sectional study was conducted in Shantou,China,in which a total of 5662 students aged 6 to 18 were *** these students who has high risks for obesity-related disease,blood specimens were collected for a test of blood lipid,blood glucose,insulin resistance (HOMA-IR).Furthermore,a self-assessment matching questionnaire was carried out in 972 students paired off with their parents.
FGF21 is a hormone produced in liver and fat that dramatically improves insulin sensitivity and lipid *** of FGF21 to obese mice leads to increased fat utilization and energy expenditure and reduced plasma glucose,ins...
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FGF21 is a hormone produced in liver and fat that dramatically improves insulin sensitivity and lipid *** of FGF21 to obese mice leads to increased fat utilization and energy expenditure and reduced plasma glucose,insulin,and serum lipid and hepatic triglyceride *** hormone(T3) also influences diverse lipid and glucose metabolic pathways by binding to
Background:and Methods:Improvement in diabetes care requires a systematic evidence-based approach that addresses organization,innovation,measurement and incentives in a structured *** Diabetes Management(SDM) was sele...
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Background:and Methods:Improvement in diabetes care requires a systematic evidence-based approach that addresses organization,innovation,measurement and incentives in a structured *** Diabetes Management(SDM) was selected by the diabetes care team at a large multi-specialty medical center in Nanjing,China as the means by which to improve
Background:Our previous study found that blocking nuclear factor(NF)-κB signaling could protect human umbilical vein endothelial cells(HUVECs) from apoptosis and proliferation inhibition due to either continuous or i...
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Background:Our previous study found that blocking nuclear factor(NF)-κB signaling could protect human umbilical vein endothelial cells(HUVECs) from apoptosis and proliferation inhibition due to either continuous or intermittentκB pathway on HUVECs induced by intermittent HG(a daily alternating 5.5 or 30.5 mmol/l glucose).high glucose(HG).Intermittent HG makes glucose toxicity more *** this study,we further investigate the effect of NF-
Background:and study aims:Delayed gastric emptying (DGE)is the commonest gastrointestinal(GI)complication in type 2 *** aimed to evaluate the association between DGE and cardiovascular autonomic neuropathy(CAN)in type...
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Background:and study aims:Delayed gastric emptying (DGE)is the commonest gastrointestinal(GI)complication in type 2 *** aimed to evaluate the association between DGE and cardiovascular autonomic neuropathy(CAN)in type 2 *** and methods:A total of 7 1 Chinese patients
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