目的 观察甘精胰岛素联合格列美脲治疗2型糖尿病临床疗效.方法 选择确诊为2型糖尿病患者140例,随机分为观察组和对照组,观察组70例,采用胰岛素联合格列美脲治疗;治疗组70例,采用格列美脲治疗;治疗12周,观察空腹血糖(FPG)、餐后2h血糖(2 h PG)、糖化血红蛋白(HbA1c)、体质指数(BMI)等指标.
Cholesterol is synthesized from acetyl-CoA through a cascade of enzymatic ***-CoA reductase (HMGCR) is the rate-limiting enzyme in this *** stability of HMGCR is regulated by sterols and this is a major mechanism cont...
Cholesterol is synthesized from acetyl-CoA through a cascade of enzymatic ***-CoA reductase (HMGCR) is the rate-limiting enzyme in this *** stability of HMGCR is regulated by sterols and this is a major mechanism controlling choles terol *** past few years,we and others have illustrated the pathway of sterol-regulated degradation of ***78 is a mem brane-anchored ubiquitin *** forms complex with Insig and other *** promotes HMGCR to bind Insig and gp78 modi fies *** Ubiquitinated HMGCR is subsequently degraded by proteasome.
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