A lack of sensitive and specific biomarkers is a major reason for the high rate of primary hepatocellular carcinoma(HCC)-related mortality. The aim of this study was to investigate potential proteomic biomarkers speci...
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A lack of sensitive and specific biomarkers is a major reason for the high rate of primary hepatocellular carcinoma(HCC)-related mortality. The aim of this study was to investigate potential proteomic biomarkers specific for *** serum samples were collected with informed consent from 80 HCC patients with HBV (+)/cirrhosis(+),80 patients with benign diseases
The major histocompatibility complex(MHC) class I-related molecular A(MICA) is a stress-induced antigen and plays a key role in anti-infectious and anti-tumoral immune *** this study,we investigate the MICA transmembr...
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The major histocompatibility complex(MHC) class I-related molecular A(MICA) is a stress-induced antigen and plays a key role in anti-infectious and anti-tumoral immune *** this study,we investigate the MICA transmembrane polymorphism in hepatocellular carcinoma(HCC) patients in south China Han *** found that the MICA-A5.1 allele,
Background:ChREBP regulates lipogenesis and glucose utilization in the *** suggested a contradictive association between rs3812316 in this gene and Triglyceride *** hypothesized ChREBP gene polymorphisms be associated...
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Background:ChREBP regulates lipogenesis and glucose utilization in the *** suggested a contradictive association between rs3812316 in this gene and Triglyceride *** hypothesized ChREBP gene polymorphisms be associated with CAD. Methods:The ChREBP gene polymorphisms were analyzed by polymerase chain reaction-restriction fragment length polymorphism(PCR-RFLP) methods in 200 controls and 310 CAD patients in
Objective To study blood culture,procalcitonin (PCT) and high sensitivity C-reactive protei(hs -CRP) in the diagnostic value of neonatal sepsis. Methods 109 cases for clinical diagnosis of newborn infants do hospital ...
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Objective To study blood culture,procalcitonin (PCT) and high sensitivity C-reactive protei(hs -CRP) in the diagnostic value of neonatal sepsis. Methods 109 cases for clinical diagnosis of newborn infants do hospital sepsis blood culture,at the same time,we detected the concentration of PCT and hs-CRP *** samples from
Background Duchenne muscular dystrophy (DMD) and Becker muscular dystrophy(BMD) are X-linked recessive disorders caused by mutations of the DMD gene located at ***. DMD/BMD is a lethal/severe X-linked recessive disord...
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Background Duchenne muscular dystrophy (DMD) and Becker muscular dystrophy(BMD) are X-linked recessive disorders caused by mutations of the DMD gene located at ***. DMD/BMD is a lethal/severe X-linked recessive disorder affecting 1 in 3500(DMD) and 1 in 30,000 (BMD) male *** is rapidly progressive, with affected boys being wheelchair-bound by age
This study aimed to compare the ability of linezolid and vancomycin to prevent the clinical methicillin-resistant Staphylococcus aureus (MRSA) resistant mutant by determining mutant prevention concentration(MPC).We fu...
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This study aimed to compare the ability of linezolid and vancomycin to prevent the clinical methicillin-resistant Staphylococcus aureus (MRSA) resistant mutant by determining mutant prevention concentration(MPC).We further investigated the possible molecular mechanism associated with reduced vancomycin susceptibility in the mutant strains by molecular fingerprinting ***-six clinical MRSA isolates were
Background China is one of the high burden countries of Mycobacterium tuberculosis infection. One challenge for tuberculosis(TB) control is the earlier diagnosis of *** based on PCR have shown promise for the detectio...
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Background China is one of the high burden countries of Mycobacterium tuberculosis infection. One challenge for tuberculosis(TB) control is the earlier diagnosis of *** based on PCR have shown promise for the detection of M. tuberculosis in different clinical samples except
Objective It is well-known that high-density lipoprotein（HDL） can be separated into two major subtractions:HDL and HDL on the basis of density by *** HDL3 exerts more powerful antioxidative effects against low-densi...
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Objective It is well-known that high-density lipoprotein（HDL） can be separated into two major subtractions:HDL and HDL on the basis of density by *** HDL3 exerts more powerful antioxidative effects against low-density lipoprotein（LDL） oxidation than HDL,the *** of HDL2,but not of HDL,were impaired in patients with coronary
Objective To investigate the effects of a proliferation-inducing ligand(APRIL ) gene silencing by small interfering RNA(siRNA) on cell cycle and proliferation of colon carcinoma SW480 cells. Methods The siRNA plasmid ...
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Objective To investigate the effects of a proliferation-inducing ligand(APRIL ) gene silencing by small interfering RNA(siRNA) on cell cycle and proliferation of colon carcinoma SW480 cells. Methods The siRNA plasmid vector targeting APRIL gene,named as siRNA-APRIL,was transfected into SW480 cells,transfected with scrambled vector as a Nontargeting control and
Purpose This study was designed to detect NDM-1 metallo-β-lactamase gene in enterobacter and Acinetobacter baumannil which showed lower resistance to carbapenems antibiotics. Methods Modified Hodge test and EDTA syne...
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Purpose This study was designed to detect NDM-1 metallo-β-lactamase gene in enterobacter and Acinetobacter baumannil which showed lower resistance to carbapenems antibiotics. Methods Modified Hodge test and EDTA synergy experiment were employed to screen those enterobacter and Acinetobacter baumannil which had lower resistance to carbapenems antibiotics
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