Objectives Opportunistic pathogen of the species Acinetobacter baumannii(***) are ubiquitous in the environment,and because capable of resistance to antibiotics,*** was recognized to take responsibility for nosocomial...
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Objectives Opportunistic pathogen of the species Acinetobacter baumannii(***) are ubiquitous in the environment,and because capable of resistance to antibiotics,*** was recognized to take responsibility for nosocomial infections,especially after disaster. Methods *** strains were collected from July to October 2007 for common patients and May 2008 victims after Wenchuan earthquake broken. Properties of antibiotic susceptibility and
Sinomenine(SIN) is a bioactive component derived from a Chinese medicinal plant that has been utilized by Chinese doctors to treat inflammatory and arthritic diseases for more than a thousand *** studies have shown ma...
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Sinomenine(SIN) is a bioactive component derived from a Chinese medicinal plant that has been utilized by Chinese doctors to treat inflammatory and arthritic diseases for more than a thousand *** studies have shown mat SIN has cytotoxic effects on human lung cancer cells. However,the antitumor molecular mechanisms of SIN have yet to be elucidated in *** evaluated the effects of SIN on the growth and
Background & objective Adiponectin is a 244 amino acid protein containing a collagen like fibrous domain and a globular C1q like C-terminal domain,and which is abundantly secreted by *** gene coding for adiponecti...
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Background & objective Adiponectin is a 244 amino acid protein containing a collagen like fibrous domain and a globular C1q like C-terminal domain,and which is abundantly secreted by *** gene coding for adiponectin, designated by the Human Genome Organization as ADIPOQ,is located on chromosome *** region has shown linkage to T2MD,metabolic syndrome and coronary artery *** the past decade,ADIPOQ was proved to be very polymorphic.A common variant of the ADIPOQ
Previous studies demonstrated that cancer sera contain antibodies which react with a unique group of autologous cellular antigens called tumor-associated antigens(TAAs).This study determines whether a mini-array of mu...
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Previous studies demonstrated that cancer sera contain antibodies which react with a unique group of autologous cellular antigens called tumor-associated antigens(TAAs).This study determines whether a mini-array of multipleTAAs would enhance antibody detection and be a useful approachin colon cancer detection and diagnosis. The mini-array of multiple TAAs was composed of five TAAs including Imp1,p62,Koc,p53 and
BACKGROUND Many research has reported the correlation between sample-to-cutoff(S/CO) ratios of anti-HCV screening test and confirmed HCV infection for American anti-HCV screening kits as well as ***,it is still a prob...
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BACKGROUND Many research has reported the correlation between sample-to-cutoff(S/CO) ratios of anti-HCV screening test and confirmed HCV infection for American anti-HCV screening kits as well as ***,it is still a problem whether the other laboratories work out the same threshold S/CO ratios under routine conditions or whether the threshold S/CO ratios
Objectives Chinese Tibetans have lived in most extreme environments with altitudes exceeding 4000 m for 5000～7000 years,and there are evidences show that they possess heritable adaptations to their hypoxic environmen...
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Objectives Chinese Tibetans have lived in most extreme environments with altitudes exceeding 4000 m for 5000～7000 years,and there are evidences show that they possess heritable adaptations to their hypoxic environment,such as high hemoglobin levels and high RBC counts, which may increase the risk of coronary artery *** there is no report about the higher morbidity of atherosclerosis or venous
Objective To investigate two single nucleotide polymorphism sites of TLR-9 and to detect their relationship with SLE in Shandong Han population. Methods The polymorphisms(rsl87084C/T、rs352139A/G)were detected with PC...
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Objective To investigate two single nucleotide polymorphism sites of TLR-9 and to detect their relationship with SLE in Shandong Han population. Methods The polymorphisms(rsl87084C/T、rs352139A/G)were detected with PCR-RFLP in 92 SLE and 88 healthy *** genotype and allele frequencies were calculated and analyzed. Results(1)The genotype frequencies of CC,CT and TT in rsl87084 site in SLE were 0.185,0.413
Objective Hepatitis B virus(HBV) infection is a world-wide health *** major obstacles for current anti-HBV therapy are the low efficacy and the occurrence of drug resistant HBV mutations. Recent studies have demonstra...
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Objective Hepatitis B virus(HBV) infection is a world-wide health *** major obstacles for current anti-HBV therapy are the low efficacy and the occurrence of drug resistant HBV mutations. Recent studies have demonstrated that combination therapy can enhance antiviral efficacy and overcome the ***,the inhibitory effect mediated by combination of small interfering RNAs(siRNAs) targeting different sites of HBV nuclear localization signal(NLS) was monitored in HepG2.2.15 cells.
Background Helicobacter pylori infection is different between children and adults,not only in infection rate but also in virulence genotypes. However,the 3' region of CagA,important in stomach carcinogenesis,still...
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Background Helicobacter pylori infection is different between children and adults,not only in infection rate but also in virulence genotypes. However,the 3' region of CagA,important in stomach carcinogenesis,still remains unclear in *** present study was to compare the frequency of cagA and the distribution of its subtypes between children and adults in South China.
Objectives To investigate the pathogenic characteristics in bloodstream infections(BSIs) in West China Hospital. Methods A retrospective analysis of the microbiological results of blood culture and clinical data of BS...
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Objectives To investigate the pathogenic characteristics in bloodstream infections(BSIs) in West China Hospital. Methods A retrospective analysis of the microbiological results of blood culture and clinical data of BSIs from Jan 2009 to Mar 2010 was conducted at West China Hospital. Results A total of 834 organisms were identified from the 826 episodes of the bloodstream infections during the study *** organisms were most
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