Objectives Human cell free circulating DNA (cf-DNA) derives mainly from both cell apoptosis and necrosis and may be measured by different laboratory techniques,but almost all these methods need sample ***,we developed...
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Objectives Human cell free circulating DNA (cf-DNA) derives mainly from both cell apoptosis and necrosis and may be measured by different laboratory techniques,but almost all these methods need sample ***,we developed a branched DNA(bDNA) - based Alu assay for quantify cf-DNA in myocardial infarction(MI) and evaluated in this study.
Background Candida tropicalis has been identified as the most prevalent yeast species of the *** azole resistance,especially fluconazole resistance,has been insufficiently found in the yeast Candida *** study aimed to...
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Background Candida tropicalis has been identified as the most prevalent yeast species of the *** azole resistance,especially fluconazole resistance,has been insufficiently found in the yeast Candida *** study aimed to investigate the molecular mechanisms responsible for fluconazole resistance in clinical isolates of this pathogenic yeast. Methods A total of 41 Candida tropicalis strains were collected from the clinical laboratory of Tai Yuan City central *** susceptibility testing was performed by ATB
Objective The aim of the present study is to investigate the serum and bronchoalveolar lavage fluid(BALF) interleukin-18(IL-18) levels in sarcoidosis and idiopathic pulmonary fibrosis(IPF) and to assess the clinical u...
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Objective The aim of the present study is to investigate the serum and bronchoalveolar lavage fluid(BALF) interleukin-18(IL-18) levels in sarcoidosis and idiopathic pulmonary fibrosis(IPF) and to assess the clinical usefulness of IL-18 in these diseases. Methods Serum and BALF levels of IL-18 were measured in 15 patients with sarcoidosis,10 patients with IPF and 24 control subjects(8 with lung tumor,6 with pulmonary tuberculosis and 10
Purpose To investigate targeting activity of the peptide(named P1c) derived from connective tissue growth factor(CTGF) toαvβ3-rich tumor cells. Materials and Methods P1c was synthesized and conjugated with ultra sup...
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Purpose To investigate targeting activity of the peptide(named P1c) derived from connective tissue growth factor(CTGF) toαvβ3-rich tumor cells. Materials and Methods P1c was synthesized and conjugated with ultra superparamagnetic iron oxide particles(USPIOs) coated with meso-2, 3-dimercaptosuccinic acid(DMSA).The specific binding activity of P1c-USPIOs toαvβ3 was
Objectives Carbapenems have a broad spectrum of activity against the drug-resistant ***,an increasing number of Enterobacteriaceae producing Klebsiella pneumoniae carbapenemases(KPC) were reported in the *** our study...
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Objectives Carbapenems have a broad spectrum of activity against the drug-resistant ***,an increasing number of Enterobacteriaceae producing Klebsiella pneumoniae carbapenemases(KPC) were reported in the *** our study,we aimed to investigate the molecular epidemiology and mechanism of carbapenem-resistant Enterobacteriaceae isolates collected from West China Hospital,Sichuan University.
Objective To compare and analysis the sensitivity,specificity,and influencing factors between the Iris iQ200 Automated Urine Microscopy Analyzer and the Sysmex UF-100 flow cytometer of the casts'detection. Methods...
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Objective To compare and analysis the sensitivity,specificity,and influencing factors between the Iris iQ200 Automated Urine Microscopy Analyzer and the Sysmex UF-100 flow cytometer of the casts'detection. Methods Three hundred and twenty cases of dry chemical urine protein + and above morning urine samples were *** urine samples were respectively examined by manual microscopy and
Background MicroRNAs(miRNAs) play important roles in the pathogenesis of tumors. Single nucleotide polymorphism(SNP) within miRNAs can change their phenotype and *** attempted to analyze the relationship between two S...
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Background MicroRNAs(miRNAs) play important roles in the pathogenesis of tumors. Single nucleotide polymorphism(SNP) within miRNAs can change their phenotype and *** attempted to analyze the relationship between two SNP loci in miRNA and colorectal cancer(CRC) in Chinese Han population. Methods Using polymerase chain reaction-restriction fragment length polymorphism(PCR-RFLP),we analyzed two
Enzyme-linked immunosorbent assay(ELISA) usually tolerates a narrow range to quantify an analyte of *** routine practice,activities of enzymes as labels in ELISA are exclusively measured by the classical initial rate ...
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Enzyme-linked immunosorbent assay(ELISA) usually tolerates a narrow range to quantify an analyte of *** routine practice,activities of enzymes as labels in ELISA are exclusively measured by the classical initial rate method using synthetic chromogenic *** to potential interference from contaminants in these chromogenic substrates,their cost and potential substrate-inhibition,practical substrate levels are
Background An increasing amount of evidence suggests that interleukin-18(IL-18) plays a pivotal role in an activation of the immune response system including the T helper 1(Th1) response,which may be related to the pa...
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Background An increasing amount of evidence suggests that interleukin-18(IL-18) plays a pivotal role in an activation of the immune response system including the T helper 1(Th1) response,which may be related to the pathophysiology of schizophrenia. However,the association between single polymorphisms of IL-18 gene and the development of schizophrenia has not been clearly ***
Objective Skp2 is frequent amplified and overexpressed in breast cancer,making Skp2 a potential molecular target for cancer *** objective of this study was to examine the effect of PPARγoverexpression on Skp2 express...
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Objective Skp2 is frequent amplified and overexpressed in breast cancer,making Skp2 a potential molecular target for cancer *** objective of this study was to examine the effect of PPARγoverexpression on Skp2 expression regulation in breast cancer cell *** this study, we investigated the role of PPARγand Skp2 in human breast cancer progression. Methods Immunohistochemical analysis was
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