X-ray crystallography is a traditional technique used for determining the atomic and molecular structure of proteins especially of small proteins(1 MDa),Cryo-EM is a very useful *** 2012,the advent of new electron det...
X-ray crystallography is a traditional technique used for determining the atomic and molecular structure of proteins especially of small proteins(<500 k Da).As for structure studies of mediumand large-sized protein complexes(>1 MDa),Cryo-EM is a very useful *** 2012,the advent of new electron detectors and improved computational programs together with substantial
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