Mitofusins are dynamin-related GTPases essential for mitochondrial *** are embedded in the mitochondrial outer membrane(OMM)and thought to fuse adjacent mitochondria via concerted oligomerization and GTP ***,the molec...
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Mitofusins are dynamin-related GTPases essential for mitochondrial *** are embedded in the mitochondrial outer membrane(OMM)and thought to fuse adjacent mitochondria via concerted oligomerization and GTP ***,the molecular mechanisms of mitofusin-mediated OMM fusion are still *** determined crystal structures of engineered
Defects in two-dimensional monolayer molybdenum disulphide(and other transition metal dichalcogenide)may be responsible for large variation of electric and optical *** this talk,I will firstly present a joint experim...
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Defects in two-dimensional monolayer molybdenum disulphide(and other transition metal dichalcogenide)may be responsible for large variation of electric and optical *** this talk,I will firstly present a joint experiment–theory investigation of point defects in monolayer MoS2
Chromatin remodelers,including Snf2,ISWI,Chd1 and Swr1 subfamilies proteins,control a myriad of nucleic acid transactions by sliding,removing and reconstructing nucleosomes in eukaryotic *** share two Rec A-like core ...
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Chromatin remodelers,including Snf2,ISWI,Chd1 and Swr1 subfamilies proteins,control a myriad of nucleic acid transactions by sliding,removing and reconstructing nucleosomes in eukaryotic *** share two Rec A-like core domains,which couple ATP hydrolysis and DNA translocation to chromatin *** activity of the catalytic core is regulated by different
Dihydrofolate reductase(DHFR)catalyzes the NADPH-dependent reduction of dihydrofolate(DHF)to tetrahydrofolate(THF).The first step in the mechanism involves proton donation to the N5 atom of *** inability to determine ...
Dihydrofolate reductase(DHFR)catalyzes the NADPH-dependent reduction of dihydrofolate(DHF)to tetrahydrofolate(THF).The first step in the mechanism involves proton donation to the N5 atom of *** inability to determine the protonation states of active site residues and substrate has led to a lack of consensus regarding the catalytic mechanism *** resolve this
Ethylene is an important *** its diverse functions,ethylene promotes the ripening of fruits and senescence of flowers thereby reducing their shelf lives.A specific ethylene biosynthesis inhibitor would help decrease p...
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Ethylene is an important *** its diverse functions,ethylene promotes the ripening of fruits and senescence of flowers thereby reducing their shelf lives.A specific ethylene biosynthesis inhibitor would help decrease postharvest loss.1-Aminocyclopropatie-1-carboxylate(ACC)oxidase(ACO)catalyzed the last step in the ethylene biosynthesis process.
Surface treatment by oxidizing the plates is a modification of the crystallization plates for protein crystallization screening to promote protein crystallization ***,further experiments proved that the amount of oxid...
Surface treatment by oxidizing the plates is a modification of the crystallization plates for protein crystallization screening to promote protein crystallization ***,further experiments proved that the amount of oxidants and treatment process are necessary for the effect of surface treatment that lead to the consequence of protein crystallization *** order to
The 2-carboxy-6-hydroxyoctahydroindole(Choi)moiety is an essential residue for the antithrombotic activity of aeruginosins,which are a class of cyanobacterial derived bioactive linear *** biosynthetic pathway of Choi ...
The 2-carboxy-6-hydroxyoctahydroindole(Choi)moiety is an essential residue for the antithrombotic activity of aeruginosins,which are a class of cyanobacterial derived bioactive linear *** biosynthetic pathway of Choi moiety has not been *** F is a putative reductase,which was indicated to be involved in the biosynthesis of Choi ***,
Antibiotic resistance is becoming one of the most catastrophic threats to human health worldwide and this problem is particularly acute in China because of antibiotic *** to Antimicrobial Resistance Global Report(WHO,...
Antibiotic resistance is becoming one of the most catastrophic threats to human health worldwide and this problem is particularly acute in China because of antibiotic *** to Antimicrobial Resistance Global Report(WHO,2014),five of the top seven most prevalent drug-resistant bacterial strains are *** uniqueness of Gram-negative bacteria lies in
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