Objective To investigate the effect of 12C heavy ion irradiation on telomerelength in culture human *** Culture human lymphocyte line Peng-EBVwere exposed to 12C heavy ion at the irradiation doses of 0.1 Gy, 0.5 Gy, 1...
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Objective To investigate the effect of 12C heavy ion irradiation on telomerelength in culture human *** Culture human lymphocyte line Peng-EBVwere exposed to 12C heavy ion at the irradiation doses of 0.1 Gy, 0.5 Gy, 1.0 Gy, 2.0 Gyand the dose rate was 0.3-0.5 Gy/min., respectively.
RNA-binding proteins(RBPs)not only serve as structural elements for mRNA packaging and transportation,but also have essential roles in mediating the function of mRNA in its entire life ***,we report a systematic strat...
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RNA-binding proteins(RBPs)not only serve as structural elements for mRNA packaging and transportation,but also have essential roles in mediating the function of mRNA in its entire life ***,we report a systematic strategy for comprehensive enrichment and identification of potential RNA-binding proteins from mammal tissue by
The very large G protein-coupled receptor 1 (VLGR1) is a core component in inner ear haircell development, Mutations in the vlgr1 gene cause Usher syndrome, the symptoms ofwhich include congenital hearing loss and pro...
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The very large G protein-coupled receptor 1 (VLGR1) is a core component in inner ear haircell development, Mutations in the vlgr1 gene cause Usher syndrome, the symptoms ofwhich include congenital hearing loss and progressive retinitis pigmentosa.
G protein-coupled receptors(GPCRs)are the largest group of the cell membrane receptorsplaying critical biological *** genome encodes approximately 400 nonolfactory *** far,the endogenous ligands of approximately120 GP...
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G protein-coupled receptors(GPCRs)are the largest group of the cell membrane receptorsplaying critical biological *** genome encodes approximately 400 nonolfactory *** far,the endogenous ligands of approximately120 GPCRs are remainedun known and these receptors are termed as orphan ***/peptide ligandsactivate about
Many pathogens including RNA viruses(*** C Virus)and intracellular bacteria(*** tuberculosis and Salmonella)usually cause chronic or latent infection in *** pathogens-surface glycans have been implicated as an immunos...
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Many pathogens including RNA viruses(*** C Virus)and intracellular bacteria(*** tuberculosis and Salmonella)usually cause chronic or latent infection in *** pathogens-surface glycans have been implicated as an immunosuppressive epitopes of pathogens and might contribute to chronic or latent
Controversial roles of FOXP3 in different cancers have been reported previously, while itsrole in gastric cancer is largely *** we found that FOXP3 is unexpectedly upregulatedin some gastric cancer cells and remains t...
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Controversial roles of FOXP3 in different cancers have been reported previously, while itsrole in gastric cancer is largely *** we found that FOXP3 is unexpectedly upregulatedin some gastric cancer cells and remains the tumor suppressor role in gastriccancer in basal condition.
Dosage compensation processes evolved to balance genome expression in species with sex chromosome *** flies,the male-specific lethal(MSL)complex exclusively localizes at the single X chromosome in males where it doubl...
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Dosage compensation processes evolved to balance genome expression in species with sex chromosome *** flies,the male-specific lethal(MSL)complex exclusively localizes at the single X chromosome in males where it doubles transcription levels through histone *** MSL complex first binds to hundreds of High Affinity Sites and then spreads to nearby active *** MSL recognition
The selective enrichment toward glycoprotein/glycopeptide is an important prerequisite for MS-based N-glycoproteome *** selective enrich the glycopeptides,our group developed two new hydrazide functionalized nanomater...
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The selective enrichment toward glycoprotein/glycopeptide is an important prerequisite for MS-based N-glycoproteome *** selective enrich the glycopeptides,our group developed two new hydrazide functionalized nanomaterials to realize solid-phase extraction of N-glycoproteome.A new type of hydrazide functionalized core-shell nanocomposite was facilely synthesized,with a out layer of abundant hydrazide
Bacterial pathogens inject virulent effector proteins into host cells to inhibit or manipulate host cellular *** previous demonstrates that these effectors often harbor potent enzymatic activities and induce novel pos...
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Bacterial pathogens inject virulent effector proteins into host cells to inhibit or manipulate host cellular *** previous demonstrates that these effectors often harbor potent enzymatic activities and induce novel posttranslational modifications on key host signaling *** example,the OspF effector from Shigella flexneri employs a MAPK phosphothreonine lyase activity to block host MAPK signaling and IL-8
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