Sheep pulmonary adenomatosis(SPA) is a naturally occurring pulmonary neoplasm of *** establish the experimental model of SPA in native lambs and to gain insight into the differences in pathogenesis between naturally o...
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Sheep pulmonary adenomatosis(SPA) is a naturally occurring pulmonary neoplasm of *** establish the experimental model of SPA in native lambs and to gain insight into the differences in pathogenesis between naturally occurring and experimentally induced SPA,two naturally occurring cases(Poll Dorset sheep,3-years old)found in Inner Mongolia were investigated and seven native neonatal lambs were inoculated intratracheally with pulmonary tumor *** cases were examined by X-ray of thorax and the dynamic changes of immunocytes were examined in their peripheral blood by flow ***,histological and ultrastructural pathology studies were *** results showed that the natural cases produce watery nasal fluid and the experimentally induced cases were showed the relative classical clinical signs of *** results for the number of lymphocytes in both cases presented a fluctuation under the continuous effect of *** results indicate that we had induced the SPA by experimentally in the native newborn lambs *** the changes of immunocytes of induced sheep,therefore,may play an important role in the pathogenesis of SPA.
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