Background:ATF6α,one of the sensor proteins in the stress signaling pathway of the endoplasmic reticulum,is located in the membrane of the endoplasmic *** date,the physiological function of ATF6a in the process of em...
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Background:ATF6α,one of the sensor proteins in the stress signaling pathway of the endoplasmic reticulum,is located in the membrane of the endoplasmic *** date,the physiological function of ATF6a in the process of embryo implantation has not been ***:In this study,the expression pattern of ATF6a in the mouse uterus during peri-implantation and the estrous cycle was detected by real-time PCR,western blot and immunohistochemistry.
Leydig cells play an important role in mammalian reproductive physiology and endocrine,the secretion of reproductive hormones are controlled by clock ***1d1(Rev-erba),one of the clock genes,is a transcription factor t...
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Leydig cells play an important role in mammalian reproductive physiology and endocrine,the secretion of reproductive hormones are controlled by clock ***1d1(Rev-erba),one of the clock genes,is a transcription factor that plays central roles in the regulation of circadian *** is still unkown that whether these clock genes exhibit a rhythmic expression and regulate testosterone production in mouse
Successful implantation is dependent on the intricate genetic and molecular dialogue between the receptive uterus and active *** of the receptive uterus is a crucial step for embryo *** this study,the expression profi...
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Successful implantation is dependent on the intricate genetic and molecular dialogue between the receptive uterus and active *** of the receptive uterus is a crucial step for embryo *** this study,the expression profiles and characterization of long non-coding RNAs(IncRNAs)in uterine samples from pregnant mice on day 4(D4U),day 5 at implantation sites(D5IU)and
Luman(also known as LZ1P and CREB3)is a transcription factor and a member of the cAMP responsive element-binding(CREB)family *** Luman has been detected in apoptotic granulosa cells and disorganized atretic bodies,the...
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Luman(also known as LZ1P and CREB3)is a transcription factor and a member of the cAMP responsive element-binding(CREB)family *** Luman has been detected in apoptotic granulosa cells and disorganized atretic bodies,the physiological function of Luman in follicular development has not been *** objective was to determine the role of Luman in foliiculogenesis
CREBZF is a member of the mammalian CREB(cAMP-response-element-binding protein)/ATF(activating transcription factor)family of the basic region-leucine zipper(bZIP)transcription *** gene produces two isoforms,SMILE-L(l...
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CREBZF is a member of the mammalian CREB(cAMP-response-element-binding protein)/ATF(activating transcription factor)family of the basic region-leucine zipper(bZIP)transcription *** gene produces two isoforms,SMILE-L(long isoform of CREBZF,also known as SMILE)and SMILE-S(short isoform of CREBZF,known as Zhangfei or ZF).Previously studies have found that Zhangfei played a suppressive role in the unfolded protein response(UPR)by interaction with Luman,
Materials and Methods: This study was conducted to investigate the dynamic distribution and possible roles of Polo-like 1 kinase (Plk1) during the first mitosis process in early porcine embryo *** immunofluorescence a...
Materials and Methods: This study was conducted to investigate the dynamic distribution and possible roles of Polo-like 1 kinase (Plk1) during the first mitosis process in early porcine embryo *** immunofluorescence and confocal microscopic imaging technique combined with western blot were used to study the dynamic expression and subcellular localization of the Plkl ***, a selective Plk1 inhibitor GSK461364 was used to evaluate the potential roles of Pik1 during this special stage.
Materials and Methods: In this study, the subcellular localization and possible roles of H3 S 10ph were evaluated in the first mitotic cell cycle progression of porcine embryos using western blot, indirect immunofluor...
Materials and Methods: In this study, the subcellular localization and possible roles of H3 S 10ph were evaluated in the first mitotic cell cycle progression of porcine embryos using western blot, indirect immunofluorescence and barasertib (H3S 10ph upstream regulator Aurora-B inhibitor) ***: H3S10ph exhibited a dynamic localization pattern and was localized to chromosomes from prometaphase to anaphase *** of porcine embryos with barasertib inhibited mitotic division at the prophase stage and was associated with a defect in chromosome condensation accompanied by the reduction of H3 S 10ph.
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