Liver cancer is the fifth most common cancer in the world and the third most common cause of cancer-related ***,50%to 55%of cases of primary liver cancer are attributable to persistent hepatitis B virus(HBV) *** HBV X...
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Liver cancer is the fifth most common cancer in the world and the third most common cause of cancer-related ***,50%to 55%of cases of primary liver cancer are attributable to persistent hepatitis B virus(HBV) *** HBV X protein(HBx) is implicated in HBV-related HCC pathogenesis,acting as a weak oncogene or a cofactor in hepatocarcinogenesis.
人类细胞中线粒体主要功能是提供人类细胞正常生命活动所需要的能量。线粒体基因组(mitochondrial DNA mtDNA),是独立于细胞核染色体外的基因组,是人体细胞内唯一的细胞核外遗传物质,人类mtDNA的遗传方式属于母系遗传,具有半自主复制特...
详细信息
人类细胞中线粒体主要功能是提供人类细胞正常生命活动所需要的能量。线粒体基因组(mitochondrial DNA mtDNA),是独立于细胞核染色体外的基因组,是人体细胞内唯一的细胞核外遗传物质,人类mtDNA的遗传方式属于母系遗传,具有半自主复制特性。由于mtDNA既无组蛋白的保护又无损伤后修复系统,这种mtDNA损伤的累积可以导致衰老的发生,并且随年龄的增长而增加。表现在mtDNA突变引起心肌衰老和生殖细胞衰老。
Department of Medical Genetics,Second Military Medical University,Shanghai,China The Third Department of Hepatic Surgery,Eastern Hepatobiliary Hospital,Second Military Medical University,Shanghai,China
Department of Medical Genetics,Second Military Medical University,Shanghai,China The Third Department of Hepatic Surgery,Eastern Hepatobiliary Hospital,Second Military Medical University,Shanghai,China
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