Stimulation ofα-adrenoceptors in the medial prefrontal cortex（mPFC）improves working memory *** improvement is accompanied by a selective increase in the activity of mPFC neurons during delay ***,the cellular mechan...
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Stimulation ofα-adrenoceptors in the medial prefrontal cortex（mPFC）improves working memory *** improvement is accompanied by a selective increase in the activity of mPFC neurons during delay ***,the cellular mechanisms responsible for this enhanced response are largely *** the present study,we recorded action potential in the pyramidal neurons of mPFC slice,using whole-cell current clamp recording *** results show that stimulation ofα-adrenoceptors enhances intrinsic excitability of neurons.
Major depressive disorder is the most common mental illness,affecting roughly 20%of the general population at some point during their *** approximately half of patients respond to existing antidepressant ***,the mecha...
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Major depressive disorder is the most common mental illness,affecting roughly 20%of the general population at some point during their *** approximately half of patients respond to existing antidepressant ***,the mechanisms underlying the pathogenesis of depression remain poorly *** is often comorbid with medical conditions such as ***,an adipocyte-derived hormone,is well known for its role in the control of energy homeostasis and body *** research has provided evidence for a novel action of leptin in the regulation of mood and *** leptin levels are reduced in chronic stress models of *** treatment reverses chronic stress-induced depression-like behavioral deficits and impairment of hippocampal *** addition,we have explored limbic leptin signaling in mood-related *** implications of leptin and leptin receptor signaling in human depression will be discussed.
＜正＞The bottom-up and top-down attentional regulation plays an important role for auditory *** track the dynamics of cortical response in an auditory stimulus discrimination task,both scalp EEG recording on normal s...
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＜正＞The bottom-up and top-down attentional regulation plays an important role for auditory *** track the dynamics of cortical response in an auditory stimulus discrimination task,both scalp EEG recording on normal subject and intracranial EEG recording on epilepsy patients undergoing subdural electrode monitoring for surgical purpose are employed to map the attentional *** low frequency event-related potential and high gamma oscillations were analyzed to obtain the property of early passive components and late active responses respectively. Moreover,these cortical neural dynamics was detected in an online fashion by machine learning algorithms to establish an auditory brain-computer interface,which is potentially useful for locked-in patients with vision impairment.
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