检索结果-内蒙古大学图书馆

您好，读者！请登录

内蒙古大学图书馆

首页
概况
党建
资源
服务
科研支持
- 论文收录引用证明
- 科技查新
知识产权
档案馆
帮助

咨询与建议

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

您的常用邮箱：*

您的手机号码：*

问题描述：

当前已输入0个字，您还可以输入200个字

全部搜索
期刊论文
图书
学位论文
标准
纸本馆藏
外文资源发现
数据库导航
超星发现

高级检索

时间限定

出版年份：

文献类型

图书期刊文献学位论文多媒体

馆藏选择

电子馆藏纸本馆藏

核心期刊

全部期刊 SCI 收录期刊 SSCI 收录期刊 EI 收录期刊 CSCD 收录期刊 CSSCI 收录期刊

语言

中文英文

文献类型

期刊文献图书学位论文标准纸本馆藏

帮助

文字说明：

T=题名（书名、题名），A=作者（责任者），K=主题词，P=出版物名称，PU=出版社名称，O=机构（作者单位、学位授予单位、专利申请人），L=中图分类号，C=学科分类号，U=全部字段，Y=年（出版发行年、学位年度、标准发布年）

检索规则说明：

AND代表“并且”；OR代表“或者”；NOT代表“不包含”；(注意必须大写,运算符两边需空一格)

检索范例：

范例一：(K=图书馆学 OR K=情报学) AND A=范并思 AND Y=1982-2016
范例二：P=计算机应用与软件 AND (U=C++ OR U=Basic) NOT K=Visual AND Y=2011-2016

分类表

所选分类

>> <<

限定检索结果

文献类型

827 篇 会议

馆藏范围

827 篇 电子文献
0 种 纸本馆藏

日期分布

学科分类号

403 篇 理学
- 403 篇 生物学
351 篇 医学
- 245 篇 临床医学
- 79 篇 基础医学(可授医学...
- 33 篇 中西医结合
- 18 篇 药学(可授医学、理...
- 8 篇 中药学(可授医学、...
- 6 篇 中医学
- 3 篇 医学技术（可授医学...
- 2 篇 公共卫生与预防医...
7 篇 工学
- 5 篇 生物医学工程（可授...
- 3 篇 生物工程
- 2 篇 材料科学与工程（可...
2 篇 教育学
- 2 篇 心理学(可授教育学...
1 篇 农学
- 1 篇 畜牧学

主题

37 篇 hippocampus
24 篇 rat
21 篇 nmda receptor
18 篇 parkinson's dise...
15 篇 ischemia
14 篇 depression
14 篇 astrocyte
14 篇 epilepsy
12 篇 alzheimer's dise...
12 篇 synaptic plastic...
12 篇 apoptosis
12 篇 microglia
12 篇 neuron
11 篇 learning and mem...
10 篇 spinal cord
9 篇 migration
9 篇 ltp
9 篇 neuroprotection
9 篇 glutamate
9 篇 帕金森病

机构

15 篇 首都医科大学
9 篇 复旦大学
8 篇 上海交通大学医学...
8 篇 neuroscience res...
6 篇 浙江大学
5 篇 中国医学科学院药...
5 篇 南通大学
4 篇 key laboratory f...
4 篇 南方医科大学
4 篇 department of ne...
4 篇 北京大学
4 篇 山西医科大学
3 篇 institute for bi...
3 篇 key laboratory f...
3 篇 华东师范大学
3 篇 南昌大学
3 篇 infectious disea...
3 篇 laboratory of ap...
2 篇 军事医学科学院基...
2 篇 department of ps...

作者

8 篇 陈生弟
8 篇 陈乃宏
7 篇 albert cheung ho...
6 篇 苑玉和
6 篇 徐志卿
5 篇 徐群渊
5 篇 孙凤艳
5 篇 胡金凤
4 篇 李鹏飞
4 篇 zhejiang provinc...
4 篇 杨予涛
4 篇 王春芳
4 篇 顾晓松
4 篇 丁健青
4 篇 college of pharm...
4 篇 刘彩玉
4 篇 陈忠
4 篇 蔚洪恩
4 篇 高天明
4 篇 key laboratory o...

语言

705 篇 英文
122 篇 中文

检索条件"任意字段=中国神经科学学会第九届全国学术会议暨第五届会员代表大会"

共 827 条记录，以下是251-260 订阅

全选清除本页清除全部题录导出标记到"检索档案"

详细简洁

排序：

Dual-peak response pattern of dimming detectors in frog retina

Dual-peak response pattern of dimming detectors in frog reti...

引用

中国神经科学学会第九届全国学术会议暨第五次会员代表大会

作者： Lei XIAO,Wei JING~+,Hai-Qing GONG,Pei-Ji LIANG~* School of Biomedical Engineering,Shanghai Jiao Tong University,Shanghai 200240,China Department of Neurology,First Hospital of Shanxi Medical University,Taiyuan 030001,China

Objective Dual-peak response of retinal ganglion cells has been observed in several species,such as chicken,turtle and *** the underlying mechanism of dual-peak response pattern is still not *** present study is to explore(1)whether dual-peak response pattern exists in dimming detectors(one type of frog retinal ganglion cells),(2)the relation between dual-peak response and different stimulus pattern,and(3)the possible mechanism of dual-peak *** Ganglion cells' firing activities were recorded using multi-electrode *** uniform visual stimulus was generated from a computer monitor and projected onto retinal surface via a lens focus *** flash stimulations with different On-Off intervals were *** pharmacological experiments,10 mM bicuculline was ***(1)Most of the dimming detectors recorded in our experiments showed the dual-peak pattern in response to flash stimulation.(2)Cells' response pattern was related with stimulus pattern.(3)The dual-peak response pattern could be modulated by exogenously applied *** The dual-peak response exists in frog retinal ganglion cells and is related to stimulus pattern,this response pattern may be related to GABAergic pathways.

关键词： retinal ganglion cells dual-peak response GABAergic pathways

来源：评论

学校读者我要写书评

暂无评论

Hippocampal neuronal nitric oxide synthase mediates the stressrelated depressive behaviors of glucocorticoids by down-regulating glucocorticoid receptor

Hippocampal neuronal nitric oxide synthase mediates the stre...

引用

中国神经科学学会第九届全国学术会议暨第五次会员代表大会

作者： Qi-Gang ZHOU~(1,#),Li-Juan ZHU~(1,#),Chen CHEN~1,Hai-Yin WU~(1,2),Chun-Xia LUO~(1,2),Lei CHANG~1,Dong-Ya ZHU~(1,2,*) 1 Department of Pharmacology,School of Pharmacy,2 Laboratory of Cerebrovascular Disease,Nanjing Medical University,Nanjing 210029,China

The molecular mechanisms underlying the behavioral effects of glucocorticoids are poorly *** report here that hippocampal neuronal nitric oxide synthase（nNOS） is a crucial *** mild stress and glucocorticoids exposures caused hippocampal nNOS overexpression via activating mineralocorticoid receptor（MR）. In turn,hippocampal nNOS-derived nitric oxide（NO） significantly down-regulated local glucocorticoid receptor （GR） expression through both soluble guanylate cyclase（sGC）/cGMP and peroxynitrite（ONOO）/extracellular signalregulated kinase（ERK） signal pathways,and thence elevated hypothalamic corticotrophin-releasing factor（CRF）,a peptide that governs the hypothalamic-pituitary-adrenal *** importantly,nNOS deletion or intrahippocampal nNOS inhibition and NO-cGMP signaling blockade（using NO scavenger or sGC inhibitor） prevented the corticosterone-induced behavioral modifications,suggesting that hippocampal nNOS is necessary for the role of glucocorticoids in mediating depressive *** addition,directly delivering ONOO donor into hippocampus caused depressive-like *** findings reveal a role of hippocampal nNOS in regulating the behavioral effects of glucocorticoids.

关键词： hippocampal neuronal nitric oxide synthase glucocorticoid receptor glucocorticoids depression

来源：评论

学校读者我要写书评

暂无评论

The C-Abl-MSTl signaling pathway mediates oxidative stress-induced neuronal cell death

The C-Abl-MSTl signaling pathway mediates oxidative stress-i...

引用

中国神经科学学会第九届全国学术会议暨第五次会员代表大会

作者： Lei XIAO,Zengqiang YUAN State Key Laboratory of Brain and Cognitive Sciences,Institute of Biophysics,Chinese Academy of Sciences,Beijing 100101,China

Oxidative stress influences cell survival and homeostasis,but the mechanisms underlying the biological effects of oxidative stress remain to be *** protein kinase MST1 plays a major role in oxidative stressinduced cell death in primary mammalian ***,the mechanisms that regulate MST1 in oxidative stress responses remain largely *** the present study,we demonstrate that the protein kinase c-Ab1 phosphorylates MST1 at Y433,which triggers the stabilization and activation of *** of c-Abl promotes the degradation of MSTl through CHIP-mediated ubiquitination,and thereby attenuates cell *** stress induces the c-Abl-dependent tyrosine phosphorylation of MST1 and increases the interaction between MST1 and FOXO3, thereby activating the MST1-FOXO signaling pathway,leading to cell death in both primary culture neurons and rat hippocampal *** identification of the c-Abl tyrosine kinase as a novel upstream activator of MST1 suggests that the c-Abl-MST1 signaling cascade plays an important role in cellular responses to oxidative stress.

关键词： c-Abl MSTl neuronal cell death signaling transduction FOXO

来源：评论

学校读者我要写书评

暂无评论

Autophagy dysfunction in Alzheimer's disease

Autophagy dysfunction in Alzheimer's disease

引用

中国神经科学学会第九届全国学术会议暨第五次会员代表大会

作者： Wei-Dong LE Ruijin Hospital,Shanghai Jiao Tong University School of Medicine

Autophagy is a lysosome degradation pathway that turns over cytoplasmic materials and helps the cell to maintain ***,it is activated under conditions of nutrient deprivation in order to enhance cell survival. Dysfunction in autophagy has been reported to contribute to several neurodegenerative *** studies have shown that both amyloidβprecursor protein and tau protein are associated with the autophagic *** processing or modification of these proteins may cause an impairment in the autophagy-lysosome pathway,which constitutively promotes the generation of amyloidβpeptides in Alzheimer's disease(AD).In addition,the impairment in the autophagy-lysosome system disturbs the turnover of other molecules associated with AD,which may also contribute to the neuronal dysfunction in *** reports related to this topic and analyzed the dynamic changes in the autophagic pathway in *** findings from the studies reviewed suggest that autophagy is altered in the early stages of the *** previous study suggested that hypoxia treatment can activate autophagy,which may contribute to the increases in Aβproduction since pretreatment with autophagy inhibitor 3-methyladenine significantly blocked chemical hypoxic condition-induced increase in Aβproduction in SH-SY5Y *** further studies reported that hypoxemia in prenatal stage can contribute to the pathogenesis of the disease of adult offspring by the autophagic pathway,supporting the notion that dysfunction in autophagy may play an important role in the pathological process of AD.

关键词： Alzheimer Autophagy dysfunction in Alzheimer's disease

来源：评论

学校读者我要写书评

暂无评论

Expression pattern of clusterin in the mouse olfactory bulb

Expression pattern of clusterin in the mouse olfactory bulb

引用

中国神经科学学会第九届全国学术会议暨第五次会员代表大会

作者： Rui-Qi WU~(1,3),Zhi-Xiang XU~(1,3),Xiao-Ping RAO~(1,3),Fu-Qiang XU~(1,2,*) 1 Wuhan MRC,State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics,Wuhan Institute of Physics and Mathematics,the Chinese Academy of Science,Wuhan 430071,China 2 Wuhan National Laboratory for Optoelectronics,Wuhan 430074,China 3 Graduate University of Chinese Academy of Science,Beijing 100049,China

Objective Clusterin is an enigmatic multifunctional glycoprotein expressed in most mammalian tissues. Some possible roles of clusterin in central nervous system(CNS)have been *** olfactory system is important in CNS for emotional responses,reproductive functions,neuroendocrine regulation,aggressive behavior, *** olfactory bulb(OB)is the center for the coding and processing of the peripheral information,and the hub for the distribution of the processed information in the olfactory *** In order to better understand the functions of this protein in the CNS,we examined the detailed distribution of clusterin in normal and anosmic mouse OB by immunohistochemical *** We found that the signals located in cell bodies at postnatal day 6 (P6),in nerve fibers at P18,and then in neurofibrils after *** addition,less clusterin protein expression was observed for anosmic mouse,except for the high level in the olfactory nerve layer(ONL).Conclusion The dynamic expression in OB at different ages and the increased expression in ONL for anosmic mice may provide important hints toward the potential functions of this protein.

关键词： clusterin olfactory bulb neuronal immunohistochemistry

来源：评论

学校读者我要写书评

暂无评论

The effect of morphine on N-cadherin expression in addiction rat VTA

The effect of morphine on N-cadherin expression in addiction...

引用

中国神经科学学会第九届全国学术会议暨第五次会员代表大会

作者： Jun-Ping CAO~(1,2,*),Hong-Jun WANG~(1,2),Jing MENG~(1,2),Jing-Ru WU~(1,2) 1 Jiangsu Province Key Laboratory of Anesthesiology and 2 Centerfor Pain Research and Treatment,Xuzhou Medical College,Xuzhou 221002,China

Objective The dopaminergic(DA)neurons in the ventral tegmental area(VTA)are widely implicated in the addiction and natural reward circuitry of the *** exposure can trigger synaptic plasticity and morphology changes in VTA DA neurons.N-cadherin is involved in the regulation of cell-cell adhesion and in morphology and plasticity *** present study was to explore whether N-cadherin expression is altered in VTA after morphine *** The co-expression of N-cadherin and DA neurons was identified by double-labelling immunofluorescence,and the alteration of N-cadherin expression was detected by RT-PCR, immunohistochemistry and Western-blot *** The results of immunofluorescence double staining showed that N-cadherin was extensively expressed in the DA neurons in the rat *** administration of morphine(5 days)resulted in a time-dependent up-regulation of N-cadherin expression at the level of mRNA and *** These data indicated that the expression of N-cadherin was up-regulated by chronic morphine and this alteration may contribute to the development of the opiate-induced changes in DA morphology and behaviors.

关键词： morphine N-cadherin DA neurons VTA

来源：评论

学校读者我要写书评

暂无评论

Up-regulation of astroglial lipid-sensitive two-pore domain potassium channel TREK-1 in rat CNS after focal ischemia

Up-regulation of astroglial lipid-sensitive two-pore domain ...

引用

中国神经科学学会第九届全国学术会议暨第五次会员代表大会

作者： Yang LIU~1,Jing-Jiao SONG~2,Ming-Huan WANG~1,Jian-Qing YUAN~1,Wei WANG~1,Zhi-Yuan YU~1,Min-Jie XIE~(1,*) 1 Department of Neurology,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology, Wuhan 430030,China 2 Division of Clinical Immunology,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430030,China

The lipid-sensitive mechano-gated TREK-1 has been shown to be predominantly expressed in the CNS. However,its regional and cellular expression under ischemic conditions remains to be *** this study,we examined the expression of TREK-1 in the rat central nervous system using an immunohistochemical approach under physiological and focal ischemia *** results show that TREK-1 was broadly expressed in the cortex, CA1 and DG region of hippocampus and subventricular ***,TREK-1 was preferentially expressed on *** focal ischemia,the TREK-1 expression was obviously increased at days 3,7 and 30 following reperfusion compared with control,which correlated with activation and proliferation of *** TREK-1 mediated K conductance establishes a low resting membrane potential for the optimal operation of astrocyte brain homeostatic functions,these data provides important insights into the astrocytic TREK-1 involvement in ischemia pathology.

关键词： TREK-1 channel astrocyte cerebral ischemia hippocampus

来源：评论

学校读者我要写书评

暂无评论

Intermittent hypoxia promotes neurogenesis in dentate gyrus of hippocampus mediated by Notch1

Intermittent hypoxia promotes neurogenesis in dentate gyrus ...

引用

中国神经科学学会第九届全国学术会议暨第五次会员代表大会

作者： Kuan ZHANG~1,Tong ZHAO~1,Xin HUANG~1,Jia SUN~1,Yun-Ling HE~1,Li-Ying WU~1,Ling-Ling ZHU~(1,*),Ming FAN~(1,*) 1 Department of Brain protection and Plasticity,Institute of Basic Medical Sciences,No.27 Taiping Rd,Beijing 100850, China

Objective Increasing evidence indicates that in vitro neurogenesis is enhanced by hypoxia,and recent studies have shown that Notch1 signaling pathway,a classic pathway regulating neurogenesis,can be activated by *** aim of this study was to investigate whether neurogenesis in dentate gyrus(DG) of hippocampus can be promoted by intermittent hypoxia(IH) and the role of Notchl in the hippocampal neurogenesis enhanced by IH. Methods The proliferation of neural stem cells(NSCs) was identified by Brdu *** differentiation and migration of NSCs were identified by Brdu and NeuN double *** morphology of astrocyte was identified by GFAP immunohistochemistry *** 1-transgenic mice were used to identified the structure of *** deficiency mice were used to identified the role of ***(1) Intermittent hypoxia could promote the neurogenesis in DG of hippocampus,including proliferation of NSCs,migration of neuron,development of spine and astrocyte.(2) The promoted effects of intermittent hypoxia on neurogenesis were inhibited in Notchl deficiency *** Intermittent hypoxia could promote the neurognesis in DG,which was mediated through Notch 1 signaling pathway.

关键词： intermittent hypoxia dentate gyrus neurogenesis Notch1

来源：评论

学校读者我要写书评

暂无评论

Neural mechanisms underlying crossmodal working memory:an EEG sLORETA study

Neural mechanisms underlying crossmodal working memory:an EE...

引用

中国神经科学学会第九届全国学术会议暨第五次会员代表大会

作者： Peng GUI,Liping WANG,Yong-Di ZHOU,Yixuan KU Institute of Cognitive Neuroscience,School of Psychology and Cognitive Science,East China Normal University, Shanghai,China

Working memory is essential to learning and performing sensory-motor behaviors that in many situations require the integration of stimuli of one modality with stimuli of *** the present study,we focused on the neural mechanisms underlying crossmodal working *** previous studies revealed that in perfonnance of the tactile crossmodal working memory task,there would be sequentially discrete task-correlated neural activities representing the processes of crossmodal working *** this study,participants performed the visual and auditory crossmodal working memory tasks while the EEG signals were *** positive event-related potential peaks LPC- 1 and LPC-2 were observed during the delay of the *** sLORETA analysis revealed that in the visual-tactile crossmodal task,LPC located in superior parietal cortex,while in the auditory-tactile crossmodal task,LPC located in supermarginal *** present study shows the sources of the late components which involved in crossmodal working *** with our former results of SI affected by crossmodal influence,this study revealed a potential processing flow from primary sensory cortices to association cortices.

关键词： Neural mechanisms underlying crossmodal working memory:an EEG sLORETA study LPC

来源：评论

学校读者我要写书评

暂无评论

Satb2 is required for dendritic arborization and soma spacing in mouse cerebral cortex

Satb2 is required for dendritic arborization and soma spacin...

引用

中国神经科学学会第九届全国学术会议暨第五次会员代表大会

作者： Lei ZHANG~(1,*),Ning-Ning SONG~1,Jia-Yin CHEN~1,Ying HUANG~1,He LI~2,Yu-Qiang DING~(1,*) 1 Department of Anatomy and Neurobiology,Tongji University School of Medicine,Shanghai 200092,China 2 Division of Histology and Embryology,Department of Anatomy,Key Laboratory of Nervous System Diseases, Ministry of Education of China,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430030,China

Self-avoidance is a mechanism by which dendrites from the same neuron repel one another in order to establish uniform coverage of the dendritic *** importance of self-avoidance for the development of complex arborization patterns has been highlighted by studies of Drosophila sensory and mouse retinal ***,it is unclear whether branch patterning in the mammalian central nervous system is also governed by this *** reduced Satb2 expression in a population of layerⅡ/Ⅲpyramidal neurons in vivo by RNA interference,and found that the somas of Satb2-deficient neurons clumped together and their dendrites failed to expand laterally but instead formed *** experiments showed that reducing Satb2 caused the adhesion of not only neighboring Satb2-deficient neurons but also neighboring wild-type *** results indicate a cell autonomous and non-cell autonomous role for Satb2 in regulating the adhesive and/or repulsive properties of cerebral pyramidal neurons.

关键词： adhesion dendritic arborization in utero electroporation repulsion self-avoidance

来源：评论

学校读者我要写书评

暂无评论

没有更多数据了...

全选清除本页清除全部题录导出标记到“检索档案”

共83页 << < 22 23 24 25 26 27 28 29 30 31 > >>

检索报告对象比较合并检索0

隐藏清空

合并搜索

回到顶部

执行限定条件

内容：

评分：

请选择保存的检索档案：

请选择收藏分类：

订阅名称：

通借通还

温馨提示：

图书名称：

借书校区：

取书校区：

手机号码：

邮箱地址：

一卡通帐号：

电话和邮箱必须正确填写，我们会与您联系确认。

联系人：

所在院系：

联系邮箱：

联系电话：

内蒙古自治区呼和浩特市赛罕区大学西街235号邮编: 010021

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：