检索结果-内蒙古大学图书馆

您好，读者！请登录

内蒙古大学图书馆

首页
概况
党建
资源
服务
科研支持
- 论文收录引用证明
- 科技查新
知识产权
档案馆
帮助

咨询与建议

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

您的常用邮箱：*

您的手机号码：*

问题描述：

当前已输入0个字，您还可以输入200个字

全部搜索
期刊论文
图书
学位论文
标准
纸本馆藏
外文资源发现
数据库导航
超星发现

高级检索

时间限定

出版年份：

文献类型

图书期刊文献学位论文多媒体

馆藏选择

电子馆藏纸本馆藏

核心期刊

全部期刊 SCI 收录期刊 SSCI 收录期刊 EI 收录期刊 CSCD 收录期刊 CSSCI 收录期刊

语言

中文英文

文献类型

期刊文献图书学位论文标准纸本馆藏

帮助

文字说明：

T=题名（书名、题名），A=作者（责任者），K=主题词，P=出版物名称，PU=出版社名称，O=机构（作者单位、学位授予单位、专利申请人），L=中图分类号，C=学科分类号，U=全部字段，Y=年（出版发行年、学位年度、标准发布年）

检索规则说明：

AND代表“并且”；OR代表“或者”；NOT代表“不包含”；(注意必须大写,运算符两边需空一格)

检索范例：

范例一：(K=图书馆学 OR K=情报学) AND A=范并思 AND Y=1982-2016
范例二：P=计算机应用与软件 AND (U=C++ OR U=Basic) NOT K=Visual AND Y=2011-2016

分类表

所选分类

>> <<

限定检索结果

文献类型

827 篇 会议

馆藏范围

827 篇 电子文献
0 种 纸本馆藏

日期分布

学科分类号

403 篇 理学
- 403 篇 生物学
351 篇 医学
- 245 篇 临床医学
- 79 篇 基础医学(可授医学...
- 33 篇 中西医结合
- 18 篇 药学(可授医学、理...
- 8 篇 中药学(可授医学、...
- 6 篇 中医学
- 3 篇 医学技术（可授医学...
- 2 篇 公共卫生与预防医...
7 篇 工学
- 5 篇 生物医学工程（可授...
- 3 篇 生物工程
- 2 篇 材料科学与工程（可...
2 篇 教育学
- 2 篇 心理学(可授教育学...
1 篇 农学
- 1 篇 畜牧学

主题

37 篇 hippocampus
24 篇 rat
21 篇 nmda receptor
18 篇 parkinson's dise...
15 篇 ischemia
14 篇 depression
14 篇 astrocyte
14 篇 epilepsy
12 篇 alzheimer's dise...
12 篇 synaptic plastic...
12 篇 apoptosis
12 篇 microglia
12 篇 neuron
11 篇 learning and mem...
10 篇 spinal cord
9 篇 migration
9 篇 ltp
9 篇 neuroprotection
9 篇 glutamate
9 篇 帕金森病

机构

15 篇 首都医科大学
9 篇 复旦大学
8 篇 上海交通大学医学...
8 篇 neuroscience res...
6 篇 浙江大学
5 篇 中国医学科学院药...
5 篇 南通大学
4 篇 key laboratory f...
4 篇 南方医科大学
4 篇 department of ne...
4 篇 北京大学
4 篇 山西医科大学
3 篇 institute for bi...
3 篇 key laboratory f...
3 篇 华东师范大学
3 篇 南昌大学
3 篇 infectious disea...
3 篇 laboratory of ap...
2 篇 军事医学科学院基...
2 篇 department of ps...

作者

8 篇 陈生弟
8 篇 陈乃宏
7 篇 albert cheung ho...
6 篇 苑玉和
6 篇 徐志卿
5 篇 徐群渊
5 篇 孙凤艳
5 篇 胡金凤
4 篇 李鹏飞
4 篇 zhejiang provinc...
4 篇 杨予涛
4 篇 王春芳
4 篇 顾晓松
4 篇 丁健青
4 篇 college of pharm...
4 篇 刘彩玉
4 篇 陈忠
4 篇 蔚洪恩
4 篇 高天明
4 篇 key laboratory o...

语言

705 篇 英文
122 篇 中文

检索条件"任意字段=中国神经科学学会第九届全国学术会议暨第五届会员代表大会"

共 827 条记录，以下是261-270 订阅

全选清除本页清除全部题录导出标记到"检索档案"

详细简洁

排序：

Transmembrane region of NMDA receptor subunit is required for receptor subunit assembly

Transmembrane region of NMDA receptor subunit is required fo...

引用

中国神经科学学会第九届全国学术会议暨第五次会员代表大会

作者： Jing-Yuan CAO~#,Jie ZHANG~#,Shuang QIU,Jie-Jie WANG,Jian-Hong LUO~* Department of Neurobiology,Zhejiang University School of Medicine,Hangzhou 310058,China

N-methyl-D-aspartate receptors(NMDARs),one of three main classes of ionotropic glutamate receptors, play major roles in synaptic plasticity,synaptogenesis and *** non-NMDA receptors,NMDARs are thought to comprise a hetero-tetrameric complex mainly composed of NRl and NR2 *** expressed alone in heterogenous cells,such as HEK293 cells,most of the NR subunits can neither leave the endoplasmic reticulum(ER) nor be expressed in the cell membrane because of the ER retention *** when NMDARs are heteromerically assembled,can the ER retention signals be masked and NMDARs be expressed in the surface ***, the mechanisms underlying NMDAR assembly remain poorly *** identify regions in subunits that mediate this assembly,we made a series of truncated or chimeric cDNA *** fluorescence resonance energy transfer(FRET) measurement in living cells,combined with immunostaining and biochemical analysis,we examined the domain-determining assembly of NMDAR *** results indicate that the transmembrane region of subunits is necessary and essential for the assembly of NMDAR subunits,both for the homomer and the heteromer.

关键词： NMDA receptor N terminus TM region FRET assembly

来源：评论

学校读者我要写书评

暂无评论

Haptic decision-making related neuronal activity in primary somatosensory cortex

Haptic decision-making related neuronal activity in primary ...

引用

中国神经科学学会第九届全国学术会议暨第五次会员代表大会

作者： Liping WANG,Xianchun LI,Peng GUI,Yong-Di ZHOU Key Laboratory of Brain Functional Genomics(Ministry of Education),Institute of Cognitive Neuroscience,East China Normal University,Shanghai 200062,China

The neuronal activity in SI cortex was collected when monkeys performed a haptic-haptic(HH) delayed matching-to-sample *** found that in trials with correct task performance a substantial number of cells showed significant differential neural activity only when the monkeys had to make a choice between two different haptic *** of incorrect trials showed that such a difference in neural activity was significantly reduced. However,the choice differential neural activity was barely observed in monkeys who performed a control task that was identical to the HH task but did not require the animal to either actively memorize the sample,or make a choice between the two objects at the end of the *** all the above results together,we believe that the differential activity may be a neural correlate of decision making,and thus conclude that some SI cells function particularly in the process of decision making when the animal has to make a haptic *** findings indicate for the first time that primary sensory cortex may play an important role in decision making.

关键词： Haptic decision-making related neuronal activity in primary somatosensory cortex

来源：评论

学校读者我要写书评

暂无评论

Identification and function analysis of novel microRNAs in rat dorsal root ganglia following sciatic nerve resection

Identification and function analysis of novel microRNAs in r...

引用

中国神经科学学会第九届全国学术会议暨第五次会员代表大会

作者： Shi-Ying LI,Bin YU,Deng-Bing YAO,Yong-Jun WANG,Fei DING,Xiao-Song GU~* Jiangsu Key Laboratory ofNeuroregeneration,Nantong University,Nantong 226001,China

Peripheral nerve injures are quite common in clinical practice and many studies have been conducted on their molecular *** is a relatively recent innovation to look for these molecular mechanisms in microRNAs (miRNAs).This paper focuses on the identification and function analysis of novel miRNAs in rat dorsal root ganglia(DRGs) following sciatic nerve resection,which is a classic model for studying peripheral nerve injures and *** Solexa sequencing,computational analysis and Q-PCR verification,114 novel miRNAs in rats were discovered and identified,of which 51 novel miRNAs were first reported in rat DRGs and 63 novel miRNAs were produced at days 1,4,7 and 14 after sciatic nerve *** further predicted target genes of these miRNAs and analyzed functional annotation of target *** data provide an important resource for the future analysis of function and regulation of miRNA,and contributes to further studies on the molecular mechanism relating to peripheral nerve injury and regeneration.

关键词： microRNAs DRGs rat solexa

来源：评论

学校读者我要写书评

暂无评论

Transient cerebral ischemia induces long-term axonopathy:Its importance for the risk of Alzheimer's disease

Transient cerebral ischemia induces long-term axonopathy:Its...

引用

中国神经科学学会第九届全国学术会议暨第五次会员代表大会

作者： Paul J.LUCASSEN Swammerdam Institute for Life Sciences Center for NeuroscienceUniversity of AmsterdamAmsterdamthe Netherlands

Objective Cerebral ischemia may contribute to the pathogenesis of Alzheimer's disease(AD),however, the neuropathological relationship between these 2 disorders is largely *** investigated axonal changes after transient cerebral ischemia/reperfusion and their relationship to the expression of Aβ42 and hyperphosphorylated Tau, which has been considered as a key neuropathological process of *** Adult Wistar rats were subjected to either sham operation or middle cerebral artery occlusion(MCAO).At the desired time after the onset of reperfusion (6 h,24 h,1 w,2 w,3 w and 4 w),animals were carried out for in vivo tracing and sacrificed for tracer detection, immunochemistry and morphological analysis of axons,and immunoblotting test for hyperphosphorylated Tau was also *** Axonal changes,consisting of swollen axons and varicosities,were found 6 h after ischemia/reperfusion in ischemic regions,such as the sensory and motor cortex and striatum,as well as the perilesional cortex and hippocampus,and were observed for up to 4 *** did not observe Aβplaques or overexpression of Aβ42 in the ischemic brain areas;nevertheless,site-specific hyperphosphorylated Tau could be detected in the ischemic *** Transient cerebral ischemia/reperfusion induces long-term axonal changes(axonopathy), which may be an important mechanism contributing to the development of AD after stroke.

关键词： cerebral ischemia axonopathy stroke Alzheimer's disease

来源：评论

学校读者我要写书评

暂无评论

Origin and molecular specification of oligodendrocytes in the spinal cord

Origin and molecular specification of oligodendrocytes in th...

引用

中国神经科学学会第九届全国学术会议暨第五次会员代表大会

作者： Meng-Sheng QIU College of Life and Environmental Sciences,Hangzhou Normal University,Hangzhou,China

Myelin is critical for the rapid conduction of action potentials in the vertebrate nervous *** oligodendrocyte is the cell type responsible for producing myelin and ensheathing axons in central nervous system (CNS).During early neural development,oligodendrocyte progenitor cells(OPCs) can be produced from a small number of neuroepithelial cells in both dorsal and ventral spinal cords,and both subpopulations of oligodendrocytes can contribute to axonal myelination during development and remyelination after *** of their embryonic origins,the development of OPCs appear to be regulated by the same set of regulatory *** Olig2 is essential for the initial specification of OPC cells,the terminal differentiation of OPCs is controlled by the Sox10 and Nkx2.2 transcription *** recent studies revealed a stage-dependent regulation of oligodendrocyte differentiation by Nkx2.2 homeodomain transcription *** myelination process is highly regulated by a number of extrinsic and intrinsic mechanisms during normal development of the oligodendrocyte *** several key factors have been identified to be critical for axonal myelination in the peripheral nervous system,the molecular control of CNS myelination has remained a *** this talk,I will present evidence that nectin-like cell adhesion molecules(Necl) and receptor molecules may participate in early CNS myelination and possibly in myelin regenerative process as well.

关键词： Origin and molecular specification of oligodendrocytes in the spinal cord

来源：评论

学校读者我要写书评

暂无评论

Stimulation of midbrain dopaminergic structures modifies firing rates of rat lateral habenula pain-activated neurons

Stimulation of midbrain dopaminergic structures modifies fir...

引用

中国神经科学学会第九届全国学术会议暨第五次会员代表大会

作者： Xue-Feng SHEN,Xiao-Guo RUAN,Hua ZHAO~* Department of Physiology,Norman Bethune College of Medicine,Jilin University,Changchun 130021,China

Ventral tegmental area and substantia nigra pars compacta are midbrain structures known to be involved in mediating *** structures give rise to dopaminergic projections that innervate the lateral habenula(LHb), which is also known to be involved in processing painful stimuli,but it's unclear what physiological effects these inputs have on habenular *** this study we distinguished the LHb pain-activated neurons and assessed their electrophysiological responsiveness to the stimulation of the ventral tegmental area and substantia nigra pars compacta with either single-pulse stimulation(300 uA,0.5 Hz) or tetanic stimulation(80 uA,25 Hz).Single-pulse stimulation that was delivered to either midbrain structure triggered transient inhibition of firing of LHb pain-activated neurons. However,tetanic stimulation of the ventral tegmental area tended to evoke an elevation in neuronal firing *** conclude that LHb pain-activated neurons can receive diverse reward-related signals originating from midbrain dopaminergic structures,and thus participate in the regulation of the brain reward system via both positive and negative feedback mechanisms.

关键词： habenula ventral tegmental area substantia nigra pars compacta reward system pain firing rate

来源：评论

学校读者我要写书评

暂无评论

Kv7/KCNQ channels are functionally expressed in oligodendrocyte progenitor cells

Kv7/KCNQ channels are functionally expressed in oligodendroc...

引用

中国神经科学学会第九届全国学术会议暨第五次会员代表大会

作者： Wei WANG,Xiao-Fei GAO,Lin XIAO,Zheng-Hua XIANG,Cheng HE~* Institute of Neuroscience and Key Laboratory of Molecular Neurobiology of Ministry of Education,Second Military Medical University,Shanghai 200433,China

Objective K7/KCNQ channels are widely expressed in neurons and they have multiple important functions,including control of excitability,spike afterpotentials,adaptation,and theta *** in KCNQ genes have been demonstrated to associate with human neurological ***,little is known about whether K7/KCNQ channels are expressed in oligodendrocyte lineage cells（OLCs）and what their functions in OLCs. The present study is aim to explore the expression and functions of K7/KCNQ channels in *** In this study,we characterized K7/KCNQ channels expression in rat primary cultured OLCs by RT-PCR,immunostaining and *** function of K7/KCNQ channels in OPCs motility was performed by Boyden chamber migration assay in ***（1）K7.2-5/ KCNQ2-5 channels expressed in OLCs.（2）The inhibition of K7/ KCNQ channels promoted OPCs motility in *** These findings showed that K7/KCNQ channels were functionally expressed in rat primary cultured OLCs and might play an important role in OPCs functioning in physiological or pathological conditions.

关键词： KCNQ potassium channels oligodendrocyte progenitor cells cell motility

来源：评论

学校读者我要写书评

暂无评论

Tbx3 and Ptfla determine the expression of receptors of neurotransmitters and nueropeptides in the dorsal spinal cord

Tbx3 and Ptfla determine the expression of receptors of neur...

引用

中国神经科学学会第九届全国学术会议暨第五次会员代表大会

作者： Zhen GUO,Jing-Wen NING,Yi-Wen BU,Ying CHEN,Zhi-Qin XIE,Xiao-Lin ZHAO,Guan-Nan XIA, Le-Ping CHENG~* Institute of Neuroscience,Shanghai Institutes for Biological Sciences,Chinese Academy of Science,Shanghai 200031, China

Neurotransmitters and neuropeptides are of most importance in vertebrate central nervous system,which mediate most of the excitatory and inhibitory neural *** evoke postsynaptic electrical responses by binding to members of a repertoire of their receptors,which excite or inhibit *** between the excitation and inhibition within dorsal horn neurons of the spinal cord may lead to chronic *** and others' previous studies have showed that transcription factors Tlx1/3 and Ptf1a control the neurotransmitter phonotype of excitatory and inhibitory neurons respectively in the dorsal spinal *** we analyzed the expression of some neurotransmitters' and neuropeptides' receptors in the dorsal spinal cord of the developing mouse embryos using in situ hybridization and fate mapping *** found most of the receptors were expressed in the dorsal horn,some of which had specific expression ***,we found Tlx1/3 and Ptf1a were required for the expression of some selected receptors,while dispensable for most of other *** studies thus show that specific receptors are subject to local master transcription factors regulation and at the mean time provide several theoretical pain control targets in the dorsal spinal cord.

关键词： receptors Tlx3 Ptfla Lbxl Pax2 dorsal horn spinal cord

来源：评论

学校读者我要写书评

暂无评论

Liver,contributes to upregulation of haptoglobin in serum from rats with traumatic brain injury

Liver,contributes to upregulation of haptoglobin in serum fr...

引用

中国神经科学学会第九届全国学术会议暨第五次会员代表大会

作者： Shu-Guang YANG,Yan-Hong MA,Yong LIU,Chang-Qiang ZHU,Meng JIANG,Shao-Jun LIU~* State Key Laboratory of Proteomics and Department of Neurobiology,Institute of Basic Medical Sciences,Beijing 100850,China

Proteomic analysis,including two-dimensional gel electrophoresis(2-DE)combined with mass spectrometry(MS),was used to compare the protein profile of serum samples from rats with traumatic brain injury(TBI) and normal ***(Hp),the acute phase response protein,showed an increased expression in rats with TBI versus normal and its change in serum was confirmed by Western ***,we found that Hp was mainly expressed in liver of rats with TBI and had an elevated mRNA *** further determine the source of the increased Hp in serum,in vitro studies using HL7702 lines and in vivo studies were *** results showed that Hp gene expression was also upregulated in HL7702 lines and liver treated with serum and brain homogenate from rats with *** findings suggest that the increased Hp in serum may result from overexpression of Hp in liver and modulated by a positive feedback loop between brain,blood and liver in response to TBI.

关键词： serum haptoglobin proteomics rat traumatic brain injury

来源：评论

学校读者我要写书评

暂无评论

GRK5 mediates F-actin bundling and targets bundles to membrane to control neuronal morphogenesis

GRK5 mediates F-actin bundling and targets bundles to membra...

引用

中国神经科学学会第九届全国学术会议暨第五次会员代表大会

作者： Yuejun CHEN,Feifei WANG,Hui LONG,Yin CHEN,Ziyan WU,Lan MA~* Pharmacology Research Center and the State Key Laboratory of Medical Neurobiology,Shanghai Medical College and Institutes of Brain Science,Fudan University,Shanghai 200032,China

Neuronal morphogenesis requires extensive membrane remodeling and cytoskeleton *** we show that GRK5,a serine/threonine kinase of G protein-coupled receptors,is critically involved in neurite outgrowth, dendrite branching,and spine morphogenesis,through promoting filopodia ***,GRK5 is not acting as a kinase,but rather provides a key link between the plasma membrane and actin ***5 promotes F-actin bundling at membranes of dynamic neuronal structures through interacting with both F-actin and PI(4,5)***,coupling regulation of actin cytoskeleton dynamics and membrane remodeling is mediated by separate domains of GRK5 and is required for its effects on neuronal ***,GRK5 knockout mice exhibit immature spine morphology and deficient learning and *** findings reveal GRK5 as a critical mediator of dendritic development and suggest that coordinated actin cytoskeleton and membrane remodeling mediated by bifunctional actin-bundling and membrane-targeting molecules such as GRK5 is crucial for proper neuronal morphogenesis and the establishment of functional neuronal circuitry.

关键词： neuronal Morphogenesis G protein-coupled receptor kinases F-actin bundling actin cytoskeleton

来源：评论

学校读者我要写书评

暂无评论

没有更多数据了...

全选清除本页清除全部题录导出标记到“检索档案”

共83页 << < 23 24 25 26 27 28 29 30 31 32 > >>

检索报告对象比较合并检索0

隐藏清空

合并搜索

回到顶部

执行限定条件

内容：

评分：

请选择保存的检索档案：

请选择收藏分类：

订阅名称：

通借通还

温馨提示：

图书名称：

借书校区：

取书校区：

手机号码：

邮箱地址：

一卡通帐号：

电话和邮箱必须正确填写，我们会与您联系确认。

联系人：

所在院系：

联系邮箱：

联系电话：

内蒙古自治区呼和浩特市赛罕区大学西街235号邮编: 010021

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：