Objective: Melatonin is involved in the regulation of circadian and seasonal rhythms and immune *** research reported low melatonin levels in autism spectrum disorders (ASD).ASMT located in pseudo-autosomal region 1 e...
Objective: Melatonin is involved in the regulation of circadian and seasonal rhythms and immune *** research reported low melatonin levels in autism spectrum disorders (ASD).ASMT located in pseudo-autosomal region 1 encodes the last enzyme of the melatonin biosynthesis pathway.A previous study reported an association between single nucleotide polymorphisms (SNPs) rs4446909 and rs5989681 located in the promoter of ASMT and ***, rare deleterious mutations were identified in a subset of patients.
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