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检索条件"任意字段=中国药学会应用药理专业委员会第三届学术会议、中国药理学会制药工业专业委员会第十三届学术会议暨2008生物医药学术论坛"
186 条 记 录,以下是171-180 订阅
排序:
Identification of the intestinal first pass elimination of berberine
Identification of the intestinal first pass elimination of b...
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中国药学会应用药理专业委员会第三届学术会议、中国药理学会制药工业专业委员会第十三届学术会议暨2008生物医药学术论坛
作者: Yitong Liu Haiping Hao Guangji Wang Li Lai Qiong Wang Key Lab of Drug Metabolism & Pharmacokinetics,China Pharmaceutical University,1 Shennong Road,Nanjing 210038,China
Objectives Intestinal first pass elimination represents a very important role in the in vivo disposition process of natural *** present study was designed to elucidate the intestinal first pass pathways in vivo and in... 详细信息
来源: 评论
Identification of Astilbin metabolites in rats by ESI-IT-TOF tandem mass spectrometry
Identification of Astilbin metabolites in rats by ESI-IT-TOF...
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中国药学会应用药理专业委员会第三届学术会议、中国药理学会制药工业专业委员会第十三届学术会议暨2008生物医药学术论坛
作者: Yan Liang An Kang Yuan Xie Lin Xie Longsheng Sheng Guangji Wang Key Lab of Drug Metabolism & Pharmacokinetics,China Pharmaceutical University,1 Shennong Road,Nanjing 210038,P.R.China
Objectives The present study was designed to investigate the in vivo and in vitro metabolism of astilbin which was the main component isohted from Rhizoma Smilacis Glabrae(RSG) and showed
来源: 评论
Metabonomic profile of the development of hypercholesterolemia to atherosclerosis in cholesterol-induced hamsters
Metabonomic profile of the development of hypercholesterolem...
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中国药学会应用药理专业委员会第三届学术会议、中国药理学会制药工业专业委员会第十三届学术会议暨2008生物医药学术论坛
作者: Weibin Zha Guangji Wang Jiye A Bei Yan Shenghua Gu Haiping Hao Qing Huang Key Laboratory of Drug Metabolism and Pharmacokinetics,China Pharmaceutical University,1 Shennong Road,Nanjing 210038,China Xuanxuan Zhu Department of Pharmacology,Clinical Research Institute of Jiangsu Provincial Hospital of Traditional Chinese Medicine,Nanjing 210029,China
Objectives Atherosclerosis is a complicated and multifactorial systemic disease,is the precursor of coronary heart *** metabolic features are of great interest because they may address pathophysiologic ***,the global ... 详细信息
来源: 评论
Cellular pharmacokinetics and disposition of tanshinoneⅡA and its sulphonate derivative:a novel mechanism for explaining their diverse cytotoxicity
Cellular pharmacokinetics and disposition of tanshinoneⅡA a...
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中国药学会应用药理专业委员会第三届学术会议、中国药理学会制药工业专业委员会第十三届学术会议暨2008生物医药学术论坛
作者: Haiping Hao Guangji Wang Xiaolan Wu Nan Cui Jing Li Key Lab of Drug Metabolism & Pharmacokinetics,China Pharmaceutical University,1 Shennong Road,Nanjing 210038,China
Objectives The anticancer activity of tanshinoneⅡA(TSA) had been confirmed by extensive research,however,the underlying mechanisms and whether its sulphonate derivative (STS) has similar anticancer activity remained ... 详细信息
来源: 评论
Inhibition of U-87 glioblastoma cell proliferation by oligomer procyanidins(F2)
Inhibition of U-87 glioblastoma cell proliferation by oligom...
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中国药学会应用药理专业委员会第三届学术会议、中国药理学会制药工业专业委员会第十三届学术会议暨2008生物医药学术论坛
作者: Feng Jiao Zhang Jing Yu Yang Chun Fu Wu Department of Pharmacology,Shenyang Pharmaceutical University,110016 Shenyang,PR China. Bao Shan Sun Estac(?)o Vitivinlcola Nacional,L-INIA,Instituto Nacional dos Recursos Biológicos,Quinta da Almoinha,2565-191 Dois Portos,Portugal Jiming Wang Laboratory of Molecular Immunoregulation,National Cancer Institute at Frederick,21702 Maryland,USA.
Objective Gliomas are the most common and lethal tumor type in the *** present study reports for the first time the potential anti-glioma activity of oligomer procyanidins (F2) (F2,degree of polymerization 2-15),a nat... 详细信息
来源: 评论
ANEPⅢ,a new recombinant neurotoxic polypeptide derived from scorpion peptide,the protective effect on rat primary cultured hippocampal and cortical neurons
ANEPⅢ,a new recombinant neurotoxic polypeptide derived from...
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中国药学会应用药理专业委员会第三届学术会议、中国药理学会制药工业专业委员会第十三届学术会议暨2008生物医药学术论坛
作者: Chun-Li Li Jing-Yu Yang Chun-Fu Wu Department of Pharmacology Jing-Hai Zhang Department of Biochemistry,Shenyang Pharmaceutical University,Shenyang 110016 Bao-Feng Yang Da-Bei Tang Department of Pharmacology,Harbin Medical University,Harbin 150086
Objective To investigate the protective effects and mechanism of the polypeptide of the scorpion venom of Buthus martensii Karsch on trauma of cells in cerebral cortex and hippocampal neurons in primary cultured *** T... 详细信息
来源: 评论
Brucea Javanica emulsion induce HL-60 cell apoptosis through intrinsic pathway
Brucea Javanica emulsion induce HL-60 cell apoptosis through...
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中国药学会应用药理专业委员会第三届学术会议、中国药理学会制药工业专业委员会第十三届学术会议暨2008生物医药学术论坛
作者: Hong Zhang Jing-Yu Yang Li-Hui Wang Wen Zhang Chun-Fu Wu Department of Pharmacology,Shenyang Pharmaceutical University,Shenyang 110016,China
Objective The anti-proliferate activity of Brucea Javanica emulsion on human leukemia cell line HL-60 and its possible mechanism were *** cell viability was determined by MTT assay;AO/EB fluorescence staining was used... 详细信息
来源: 评论
Schisandra fruit extract treatment increases plasma exposure levels of midazolam by inhibiting intestinal CYP3A
Schisandra fruit extract treatment increases plasma exposure...
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中国药学会应用药理专业委员会第三届学术会议、中国药理学会制药工业专业委员会第十三届学术会议暨2008生物医药学术论坛
作者: Li Lai Haiping Hao Guangji Wang Xijing Chen Yitong Liu Qiong Wang Key Lab of Drug Metabolism & Pharmacokinetics,China Pharmaceutical University,1 Shennong road,Nanjing,China
Objectives The present study was designed to investigate the effects of Schisandra fruit extract on the pharmacokinetics of midazolam in rats to assess the potential herbal-drug interactions involvement of CYP3A *** S... 详细信息
来源: 评论
Huanglian Jiedu Decoction modulates glucagons-like peptide(GLP)-1(7-36)amide in STZ-induced diabetic rats
Huanglian Jiedu Decoction modulates glucagons-like peptide(G...
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中国药学会应用药理专业委员会第三届学术会议、中国药理学会制药工业专业委员会第十三届学术会议暨2008生物医药学术论坛
作者: Yunli Yu Shousi Lu Sen Yu Yuchun Liu Xiaodong Liu Lin Xie Guangji Wang Key lab of drug metabolism and pharmacokinetics,China pharmaceutical university,Nanjing 210009
Objectives The purpose of the study is to investigate the effect of Huanglian Jiedu Decoction(HLJDD) on glucagons-like peptide(GLP)-1(7-36) amide level in diabetic *** Streptozotocin (STZ)-induced diabetic rats were t... 详细信息
来源: 评论
Age-dependent impairment of delay and trace eyeblink conditioning in mice
Age-dependent impairment of delay and trace eyeblink conditi...
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中国药学会应用药理专业委员会第三届学术会议、中国药理学会制药工业专业委员会第十三届学术会议暨2008生物医药学术论坛
作者: Fang Wang Chun-Fu Wu Jing-Yu Yang School of Life science and biopharmaceutics,Shenyang Pharmaceutical University,Shenyang 110016,China Shigenori Kawahara Faculty of Engineering,Toyama University 930-8555,Japan Yutaka Kirino Faculty of Pharmaceutical sciences,Tokushima Bunri University,769-2193,Japan
Objective Age-dependent impairment of delay and trace eyeblink conditioning in mice was evaluated in *** Rats were trained delay eyeblink conditioning,in which the conditioned stimulus(CS) overlaped with a coterminati... 详细信息
来源: 评论