Background: Individual variability in the therapeutic response to an antihypertensive drug could have agenetic *** investigated whether the α1A-adrenergic receptor(α1A-AR)Arg347Cys,angiotensin Ⅱ type 1 receptor(AT1...
Background: Individual variability in the therapeutic response to an antihypertensive drug could have agenetic *** investigated whether the α1A-adrenergic receptor(α1A-AR)Arg347Cys,angiotensin Ⅱ type 1 receptor(AT1R),potassium inwardly rectifying channel,subfamily J,member 11(KCNJ11)I337V,and kininogen(KNG1)Ile197Met gene polymorphisms are associated with the blood pressure(BP)therapeutic response to irbesartan and whether the association couldbe altered by the plasma irbesartan level.
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