This study was designed to investigate whether MicroRNA(miRNA)is involved in pathological processes relevant to human cardiac disease,in addition to its role in regulating *** models of myocardial infarction,hypertrop...
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This study was designed to investigate whether MicroRNA(miRNA)is involved in pathological processes relevant to human cardiac disease,in addition to its role in regulating *** models of myocardial infarction,hypertrophy and diabetes mellitus were *** levels were measured using miRNA Detection *** activities were measured with a dual luciferase reporter
Des-γ-carboxyl prothrombin(DCP)is a serum protein produced by hepatocellular carcinoma(HCC) *** and tissue DCP expressions are thought to reflect the biological malignant potential of HCC. However,the role of DCP in ...
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Des-γ-carboxyl prothrombin(DCP)is a serum protein produced by hepatocellular carcinoma(HCC) *** and tissue DCP expressions are thought to reflect the biological malignant potential of HCC. However,the role of DCP in the development of angiogenesis has not been *** this study,we evaluated the angiogenic activity of DCP in human vascular endothelial *** proliferation of human
Matrix metalloproteinase-2(MMP-2)and MMP-9 have been associated with the ability of tumor cells to metastasize due to their capacity to degrade typeⅣcollagen,the main component of basement membrane,and to their eleva...
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Matrix metalloproteinase-2(MMP-2)and MMP-9 have been associated with the ability of tumor cells to metastasize due to their capacity to degrade typeⅣcollagen,the main component of basement membrane,and to their elevated expression in malignant tumors.(S)-methyl 6- (benzyloxycarbonylamino)-2-(2-(S)-2,6-dioxo-3-(3,4,5-trimethoxybenzamido)piperidin-1-yl)
Studied the metabolism of cinnamic acid in homogenized liver of *** screen the CYP450 enzyme, which participate on metabolism of cinnamic *** then supply the evidence for rational *** content of cinnamic acid in homog...
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Studied the metabolism of cinnamic acid in homogenized liver of *** screen the CYP450 enzyme, which participate on metabolism of cinnamic *** then supply the evidence for rational *** content of cinnamic acid in homogenized liver was measured by the reversed phase *** effects of inductors and inhibitors on metabolism of cinnamic *** metabolic rate of
Brain ischemia-induced neuronal death has been linked in part to the broken of ion homeostasis. Excessive K efflux and intracellular K depletion have been hypothesized to be key steps in the apoptotic cascade of many ...
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Brain ischemia-induced neuronal death has been linked in part to the broken of ion homeostasis. Excessive K efflux and intracellular K depletion have been hypothesized to be key steps in the apoptotic cascade of many cells,including central *** light of recent evidence suggesting that an
To investigate the conversion of dl-PHPB to dl-NBP,two HPLC-UV methods were developed and validated for determination of dl-PHPB and *** quantification of dl-PHPB and dl-NBP,4- biphenylacetic acid and diazepam were us...
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To investigate the conversion of dl-PHPB to dl-NBP,two HPLC-UV methods were developed and validated for determination of dl-PHPB and *** quantification of dl-PHPB and dl-NBP,4- biphenylacetic acid and diazepam were used as the internal standard(IS),*** methanol deproteiniation,samples were separated on an Aichrom Bond-1 C18 column using methanol and
To investigate whether cAMP-dependent protein kinase（PKA）and/or Ca-calmodulin-dependent protein kinase（CaMKII）is/are involved in Rb and Rg-enhanced synapsinⅠphosphorylation and glutamate release in PC12 cells,dif...
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To investigate whether cAMP-dependent protein kinase（PKA）and/or Ca-calmodulin-dependent protein kinase（CaMKII）is/are involved in Rb and Rg-enhanced synapsinⅠphosphorylation and glutamate release in PC12 cells,differentiated or undifferentiated PC12 cells were incubated with Rb and Rg,following a 30-min pretreatment with or without H89,an inhibitor of PKA or W7,of calmodulin.
Lethal ventricular arrhythmias are a major cause of sudden death during myocardial infarction(MI).β-blockers such as metoprolol and propranolol,have demonstrated to reduce mortality rate in MI patients. A recent stud...
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Lethal ventricular arrhythmias are a major cause of sudden death during myocardial infarction(MI).β-blockers such as metoprolol and propranolol,have demonstrated to reduce mortality rate in MI patients. A recent study demonstrated arrhythmogenic potential of the muscle-specific microRNA(miRNA),miR-1 in *** investigate if the life-saving property ofβ-blockers is related to targeting miR-1,we performed a
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