Background: Hyperhomocysteinemia, an elevation of homocysteine levels in the blood, is regarded as an indepen-dent risk factor for cardiovascular and cerebral vascular disorders. Several plausible mechanisms for homoc...
详细信息
Background: Hyperhomocysteinemia, an elevation of homocysteine levels in the blood, is regarded as an indepen-dent risk factor for cardiovascular and cerebral vascular disorders. Several plausible mechanisms for homocysteine - in-duced atherosclerosis have been proposed. These include endothelial dysfunction, increased proliferation of smooth mus-cle cells, enhanced coagulability and increased cholesterol synthesis in hepatocytes. Endothelial dysfunction is considered
In spontaneously hypertensive rats(SHR), the endothelium - dependent contractions, in response to acetylcholine,involve the production oxygen - derived free radicals along with the activation of cyclooxygenase - 1 and...
详细信息
In spontaneously hypertensive rats(SHR), the endothelium - dependent contractions, in response to acetylcholine,involve the production oxygen - derived free radicals along with the activation of cyclooxygenase - 1 and TP receptors.
暂无评论