Artemisinin is an important antimalarial drug precursor obtained from the plant Artemisia annua. The complete knowledge of its biosynthetic pathway will help to improve the drug production through genetic *** recently...
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Artemisinin is an important antimalarial drug precursor obtained from the plant Artemisia annua. The complete knowledge of its biosynthetic pathway will help to improve the drug production through genetic *** recently isolated a key gene involved in artemisinin biosynthesis encoding artemisinic aldehyde delta-11(13)reductase(Dbr2)through a combination of partial protein purification,mass spectrometry,and EST *** Dbr2,it was possible to engineer
Ganoderma species,a well known traditional Chinese medicine,have been widely used for the prevention and treatment of various diseases in China,Korea,and Japan for *** research group had explored several Ganoderma spp...
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Ganoderma species,a well known traditional Chinese medicine,have been widely used for the prevention and treatment of various diseases in China,Korea,and Japan for *** research group had explored several Ganoderma spp.,and isolated 3,4-seco-nortriterpenoids from Ganoderma fornicatum and three new triterpenoids containing four-membered ring from the fruiting bodies of Ganoderma *** our continuing research on the chemical constituents of Ganoderma resinaceurn,eight triterpenoids,including five new ones,named lucidone D-G
Phenolic acids are health-promoting but low content secondary metabolites in Salvia miltiorrhiza. Based on the new multi-gene coexpression-cosupression vector system we constructed for the first time,the Arabidopsis t...
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Phenolic acids are health-promoting but low content secondary metabolites in Salvia miltiorrhiza. Based on the new multi-gene coexpression-cosupression vector system we constructed for the first time,the Arabidopsis transcription factor Production of Anthocyanin Pigment 1(AtPAP1)was expressed in ***,and meanwhile,both Cinnamoyl-CoA Reductase(CCR) and caffeic acid O-methyltransferase(COMT)genes were down-regulated by RNA interference to cut down the
Diosgenyl saponins are steroidal glycosides found as major components in many traditional oriental medicines.A number of naturally occurring diosgenyl saponins have been shown to exert cytotoxic activity against sever...
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Diosgenyl saponins are steroidal glycosides found as major components in many traditional oriental medicines.A number of naturally occurring diosgenyl saponins have been shown to exert cytotoxic activity against several strains of human cancer *** example,Dioscin(Fig.1)is one of the most common steroidal saponins and exhibits potent anticancer activity through apoptosis-inducing *** of such saponins for cancer treatment is hampered due to the lack
The secondary metabolites found in Mangroves represent an extremely rich source of novel chemical diversity for academic drug discovery and chemical biology *** is particularly true that the mangroves from Southern Co...
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The secondary metabolites found in Mangroves represent an extremely rich source of novel chemical diversity for academic drug discovery and chemical biology *** is particularly true that the mangroves from Southern Coast of China are very prolific producers of bioactive natural products. Our group at SIMM has long been engaged in the searching for novel secondary metabolites with pharmacological potential from Chinese mangrove *** collaboration with biologists and
Traditional Chinese medicines(TCMs)have been used in China for centuries in the prevention and treatment of many human diseases.A very small amount of them have been systematically investigated because of the existenc...
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Traditional Chinese medicines(TCMs)have been used in China for centuries in the prevention and treatment of many human diseases.A very small amount of them have been systematically investigated because of the existence of large numbers of complex chemical *** it is necessary to develop efficient strategies for rapid screening and identification of bioactive components from *** the last decade,many new strategies interfacing biological activity screening and high performance liquid chromatography(HPLC),characterized as
Zephyranthes candida is widely cultivated in southern China as a medicinal and ornamental plant,and it were widely used to treat diseases such as cancer and diabetes in India and *** the course of search for bioactive...
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Zephyranthes candida is widely cultivated in southern China as a medicinal and ornamental plant,and it were widely used to treat diseases such as cancer and diabetes in India and *** the course of search for bioactive alkaloids from medicinal plants,15 alkaloids were obtained from the whole plants of Zephyranthes candida by using column chromatography on silica gel,reversed phase silica gel,Sephadex LH-20 and *** 1-7 were identified to be new compounds, named as N-ethoxycarbonylethyl crinasiadine(1),N-ethoxycarbonylpropyl crinasiadine(2),
Introduction Alsophila spinulosa(*** Hook.)Tryon belongs to fern species with a unique tree-like trunk,mainly distributing in southern China,southern Japan,and southeastern *** stem part of it,named as"Long-Gu-Fe...
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Introduction Alsophila spinulosa(*** Hook.)Tryon belongs to fern species with a unique tree-like trunk,mainly distributing in southern China,southern Japan,and southeastern *** stem part of it,named as"Long-Gu-Feng"or"Gutde"in the traditional Zhuang Medicine,is used medicinally for the treatment of coughing,asthma,rheumatism,ascariasis and *** studies revealed that the leaves of *** contain flavonoids,tritepenoids and sterols.
Parasites are unusal plants,more than 2500 species of higher plants are known to live parasitically on other *** chinensis is belonging to the Loranthaceae family,distributed in Guangdong, Guangxi,Tanwan and Fujian pr...
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Parasites are unusal plants,more than 2500 species of higher plants are known to live parasitically on other *** chinensis is belonging to the Loranthaceae family,distributed in Guangdong, Guangxi,Tanwan and Fujian province in *** common host trees of *** are mulberry,plum trees,longan trees,lychee trees and oleander trees,*** from leaves and stems of this plant are used folkloric medicine in the treatment of pain in rheumatism,lack of energy
Aqueous extract of leaves and young twigs of Uncaria gambir *** been used as a spice under the name of *** has also been utilized for treatments of diarrhea and sore throats. The major constituent is(+)-catechin and t...
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Aqueous extract of leaves and young twigs of Uncaria gambir *** been used as a spice under the name of *** has also been utilized for treatments of diarrhea and sore throats. The major constituent is(+)-catechin and the presence of several chalcane-flavan dimers,which are structurally related to(+)-catechin,in gambir has also been *** some characteristic indole alkaloids such as gambirtannine have also been reported as the constituents,
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