Objective: To summarize the definition, pathophysiology, clinical menifestation, diagnosis and treatment of dystonic tremor(DT), thus to provide a better understanding of this rarely seen ***: We retrospectively analy...
Objective: To summarize the definition, pathophysiology, clinical menifestation, diagnosis and treatment of dystonic tremor(DT), thus to provide a better understanding of this rarely seen ***: We retrospectively analyzed one patient diagnosed as DT and reviewed a mass of related ***: The patient presented with static or postural tremor in both of her legs for 1 *** was diagnosed and treated as parkinson' s disease but she didn' t respond to antiparkinsonism *** examination revealed a dystonic posturing of both feet, presenting as dorsal flexure and inversion of both feet, without *** diagnosed her as DT and c]onazepam was given by 0.5 mg twice per day , which satisfactorily relieved her symtomps in our *** review demonstrated that DT was a new clinical entity without an clear definition.
Traditional oxygen-glucose deprivation (OGD) models do not produce sufficiently stable and continuous deprivation to induce cell death in the ischemic ***, we modified the OGD model to mimic the observed damage in the...
Traditional oxygen-glucose deprivation (OGD) models do not produce sufficiently stable and continuous deprivation to induce cell death in the ischemic ***, we modified the OGD model to mimic the observed damage in the ischemic core following stroke and utilized this new model to study cell death pathways in *** PO2 and pH levels in the astrocyte culture medium were compared between a physical OGD group, a chemical OGD group and a mixed OGD *** mixed OGD group was able to maintain anaerobic conditions in astrocyte culture medium for 6 h, while the physical and the chemical groups failed to maintain such *** viability decreased and LDH release into in the medium increased as a function of exposure to *** to the control group, the expression of active caspase-3 in the mixed OGD group increased within 2 h after OGD, but decreased after 2 h of ***, porimin mRNA levels did not significantly increase during the first 2 h of OGD, while bcl-2 mRNA levels decreased at 1 ***,both porimin and bcl-2 mRNA levels increased after 2 h of OGD;interestingly, they both suddenly decreased at 4 h of *** together, these results indicate that apoptosis and oncosis are the two cell death pathways responsible for astrocyte death in the ischemic ***, the main death pathway varies depending on the OGD period.
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