Purpose To characterize the clinical and genetic features of epilepsy related febrile seizures plus (EFS+) in Chinese *** A Total of 704 patients were divided into 8 groups, consisting of repetitive febrile seizure (F...
Purpose To characterize the clinical and genetic features of epilepsy related febrile seizures plus (EFS+) in Chinese *** A Total of 704 patients were divided into 8 groups, consisting of repetitive febrile seizure (FS), FS plus (FS+), generalized epilepsy with febrile seizures plus (GEFS+), partial epilepsy with febrile seizures plus (PEFS+), severe myoclonic epilepsy in infancy (SMEI), borderline SMEI(SMEB), myoclionc astatic epilepsy(MAE) and unclassified epilepsy with fever-sensitive seizures(UEFS).All patients were screened for SCN1A mutations using combined approaches including dHPLC, MPLA, direct sequencing and pyrosequencing.
Purpose: Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are rare but severe cutaneous adverse reactions (SCAR) caused by a certain number of medications including antiepileptic carbamazepine (CBZ)...
Purpose: Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are rare but severe cutaneous adverse reactions (SCAR) caused by a certain number of medications including antiepileptic carbamazepine (CBZ) and lamotrigine (LTG).Although a strong association between CBZ-SJS/TEN and HLA-B*1502 has been found in Han Chinese patients, the relationship between LTG induced-SJS/TEN and HLA-B*1502 was *** previous study indicated a potential association between HLA-A*2402 and CBZ-SJS/*** thus investigated the involvement of HLA-A, B alleles in LTG-SJS Han Chinese patients.
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