As the bridge for coorperating between PPARαand the fatty acid oxidation pathways,Carnitine palmitoyltransferase la(CPT1a)is a rate-limited enzyme for mitochondria fatty acidβ-oxidation pathway,which closely related...
详细信息
As the bridge for coorperating between PPARαand the fatty acid oxidation pathways,Carnitine palmitoyltransferase la(CPT1a)is a rate-limited enzyme for mitochondria fatty acidβ-oxidation pathway,which closely related to the ruminant growth and *** this study,one 12-bp duplicated InDel(insertion/deletion)polymorphism the CPT1a gene was identified in 700 goats,showing three genotypes designated asⅡ,ID,and *** analysis showed the locus was strongly associated with trunk index(TI)(P=0.008)and body length index(P=0.034)in Hainan balck goats,and body length(BL)(P=0.010),chest circumference(ChC)(P=0.004),chest depth(ChD)(P=0.029)and hucklebone width(HuW)(P=0.002)in Nubian goats,as well as the chest circumference(HuW)(P=0.016)in Fuqing goat *** in kid and adult goats,qRT-PCR results revealed that the CPT1a gene was expressed in all tissues with highest mRNA levels in the liver,lung,spleen,kidney,followed by the adipose,***,this is the evidences of the association between the InDel of CPTla gene and growth traits in goat,which may provide a valuable foundation for marker-assisted selection(MAS)in goat genetics and breeding.
暂无评论