Chlorpyrifos(CPF) is a pesticide that causes tens of thousands of deaths per year *** could bind with Human serum albumin(HSA) and bovine serum albumin(BSA).The binding behaviors between them were studied by fluoresce...
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Chlorpyrifos(CPF) is a pesticide that causes tens of thousands of deaths per year *** could bind with Human serum albumin(HSA) and bovine serum albumin(BSA).The binding behaviors between them were studied by fluorescence spectroscopy,three-dimensional fluorescence,CD
Aptamers are oligonucleic acid or peptide molecules that bind to wide range specific targets from metal ions,small molecules,to large proteins,even *** gold nanoparticles (AuNPs) and silver enhancement were introduced...
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Aptamers are oligonucleic acid or peptide molecules that bind to wide range specific targets from metal ions,small molecules,to large proteins,even *** gold nanoparticles (AuNPs) and silver enhancement were introduced to detect the target molecules[1]. Previous work in our group has prepared aptamer-Gold nanoparticles(Apt-AuNPs) by
The reaction mechanism of the mononuclear magnesium enzyme Phosphoserine Phosphatase(PSP) was investigated using hybrid density functional *** catalyzes the hydrolysis of phospho-L-serine (PLS)(Scheme 1).Large quantum...
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The reaction mechanism of the mononuclear magnesium enzyme Phosphoserine Phosphatase(PSP) was investigated using hybrid density functional *** catalyzes the hydrolysis of phospho-L-serine (PLS)(Scheme 1).Large quantum models are employed(141 atoms) based on an X-ray crystal
<正>Contractile forces produced by cyclic interactions between actin and myosin in overlap can transmit to extracellular matrix(Collagen) and adjacent fibers and to the heart wall to squeeze out the blood filled i...
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<正>Contractile forces produced by cyclic interactions between actin and myosin in overlap can transmit to extracellular matrix(Collagen) and adjacent fibers and to the heart wall to squeeze out the blood filled in the heart cavity through a series of *** the elastic properties influence the response of fibers
The PDBbind database is created to provide a comprehensive collection of the binding data for the biomolecular complexes deposited in the Protein Data Bank(PDB).It thus provides a link between energetic and structural...
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The PDBbind database is created to provide a comprehensive collection of the binding data for the biomolecular complexes deposited in the Protein Data Bank(PDB).It thus provides a link between energetic and structural information of biomolecular complexes,which is of great value for various studies on molecular recognition occurred in biological *** entire
The reaction mechanism of[EtN][WO(mnt)]of tungsten dependent enzyme acetylene hydratase,which catalyzes the hydration of acetylene to acetaldehyde,is studied theoretically using density functional theory(DFT).The ...
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The reaction mechanism of[EtN][WO(mnt)]of tungsten dependent enzyme acetylene hydratase,which catalyzes the hydration of acetylene to acetaldehyde,is studied theoretically using density functional theory(DFT).The tungsten complex comprises a low-spin tungsten
The outer membrane proteins(OMPs) of the Gram negative bacteria have to be translocated through the cytoplasm,the inner membrane,and the periplasmic space before reaching their final *** highly fluctuating nature of t...
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The outer membrane proteins(OMPs) of the Gram negative bacteria have to be translocated through the cytoplasm,the inner membrane,and the periplasmic space before reaching their final *** highly fluctuating nature of the periplasmic space,due to the high permeability of the outer membrane,engenders such translocation process inevitably challenging and would have to rely on an efficient quality control
H/ACA RNP(ribonucleoprotein complex) containing H/ACA RNA,Cbf5,Nop10,L7Ae,and Gar1 can guide site-specific conversion of uridine into pseudouridine in cellular *** crystal structures of H/ACA RNP with and without subs...
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H/ACA RNP(ribonucleoprotein complex) containing H/ACA RNA,Cbf5,Nop10,L7Ae,and Gar1 can guide site-specific conversion of uridine into pseudouridine in cellular *** crystal structures of H/ACA RNP with and without substrate bound are solved by Ye's ***,the kinetics of this
Chirality breaking of D- and L-alanine crystals in the c-direction of(NH…O) modes was observed by polarized Raman spectroscopy with b(cc)b geometry at *** to the Raman effects with vibrational states in the proce...
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Chirality breaking of D- and L-alanine crystals in the c-direction of(NH…O) modes was observed by polarized Raman spectroscopy with b(cc)b geometry at *** to the Raman effects with vibrational states in the process of scattering alanine crystal,the ups and downs of(NH…O) hydrogen bonding showed strong directionality in alanine *** study reveals an intrinsic chirality in
Epothilone A(EpoA) was found to be quite active against cancer cells like Taxol as a strong promoter of tubulin polymerization,when it binds to microtubule[1].To study the binding pocket of EpoA onβ-tubulin and other...
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Epothilone A(EpoA) was found to be quite active against cancer cells like Taxol as a strong promoter of tubulin polymerization,when it binds to microtubule[1].To study the binding pocket of EpoA onβ-tubulin and other characteristics,it is an important issue definitely to find the residues of active sites for EpoA binding onβ-*** docking method,molecular
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