＜正＞The advent of room-temperature single-molecule imaging and spectroscopy in the early 1990s made it possible to follow biochemical reactions of an individual molecule,such as an enzyme, in real *** experimental f...
＜正＞The advent of room-temperature single-molecule imaging and spectroscopy in the early 1990s made it possible to follow biochemical reactions of an individual molecule,such as an enzyme, in real *** experimental findings challenged the theoretical understanding of single molecule phenomena,both in terms of thermodynamics and chemical ***
Phospholipase A2(PLA2) selectively hydrolyzes the Sn-2 position of glycerophopholipids to release fatty acid and *** the fatty acid is arachidonic acid,it could be catalyzed by cyclooxygenase(COX) and lipoxygenase(LOX...
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Phospholipase A2(PLA2) selectively hydrolyzes the Sn-2 position of glycerophopholipids to release fatty acid and *** the fatty acid is arachidonic acid,it could be catalyzed by cyclooxygenase(COX) and lipoxygenase(LOX),and initiates the production of inflammatory mediato.
＜正＞Computer simulations can provide very detailed atomic or even electronic information for molecular processes,leading to significant advances in the understanding of reaction processes in complicated chemical and...
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＜正＞Computer simulations can provide very detailed atomic or even electronic information for molecular processes,leading to significant advances in the understanding of reaction processes in complicated chemical and biological *** report our recent efforts in the
＜正＞Despite improvement of computer power,all-atom molecular dynamics simulations of proteins remain *** is an active effort in developing coarse-grained protein *** present our recent progress in developing an effi...
＜正＞Despite improvement of computer power,all-atom molecular dynamics simulations of proteins remain *** is an active effort in developing coarse-grained protein *** present our recent progress in developing an efficient united-atom protein force field coupled with coarse-grained *** local conformational features of each amino acid（AA） have
We consider open driven biochemical reaction systems in a mesoscopic volume such as a single biological *** study its nonlinear,stochastic dynamics in terms of the chemical master equation(CME) whose trajectories can ...
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We consider open driven biochemical reaction systems in a mesoscopic volume such as a single biological *** study its nonlinear,stochastic dynamics in terms of the chemical master equation(CME) whose trajectories can be obtained by the Gillespie *** apply the CME theory to two of the most important biochemical networks:The gene regulatory
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