Pulmonary tuberculosis (TB) has been focused on again in recent decades because of its rising trend of incidence and meanwhile more and more researches has disclosed the relationship between the microbiota and the chr...
Pulmonary tuberculosis (TB) has been focused on again in recent decades because of its rising trend of incidence and meanwhile more and more researches has disclosed the relationship between the microbiota and the chronic infectious *** our work, we enrolled 32 patients of primary TB and they were featured by unilateral TB lesion forming when diagnosed by chest radiographic exam and from them, bronchial-alveolar lavage fluid from both sides of lungs were *** addition, 24 health people were chosen as normal control.
HCV is the causative agent of type-C hepatitis, previously known as non-A non-B type, and one of the most resilient viral infections that affects human *** high degree of virus variability and the absence of effective...
HCV is the causative agent of type-C hepatitis, previously known as non-A non-B type, and one of the most resilient viral infections that affects human *** high degree of virus variability and the absence of effective vaccines via conventional approaches stimulate much interest in the application of DNA vaccines against *** to date the reported DNA vaccines are covering almost all the constituting structural and nonstructural HCV *** of the developed applications included DNA constructs encoding a single gene or several combined gene sequences, administrated with or without adjuvants or other adjuvant-like *** techniques have been applied and evaluated for vaccine delivery which include gene gun, electroporation, microparticles, and liposomes.
Objective To investigate the protective effects of combinations of probiotic (Bifico) on interleukin-10 gene-deficient (IL-10 KO) mice, and Caco-2 cell *** IL-10 KO mice were used to assess the benefits of Bificoin **...
Objective To investigate the protective effects of combinations of probiotic (Bifico) on interleukin-10 gene-deficient (IL-10 KO) mice, and Caco-2 cell *** IL-10 KO mice were used to assess the benefits of Bificoin ***-10 KO and control mice received approximately 1.5 × l08 colony forming units (CFU) per day of Bifico for four *** were then removed and analyzed for epithelial barrier function by Ussing Chamber, while an ELISA was used to evaluate pro-inflammatory *** colon epithelial cell line, Caco-2, was used to test the benefit of Bificoin *** coli (EIEC) and the probiotic mixture Bifico, or single probiotic strains, were applied to cultured Caco-2 monolayers.
Objective This study was designed to clear the quantitatively relationship between HBeAg and HBV DNA, and verify whether quantitative measurement of HBeAg could be used as a marker of viral replication in asymptomatic...
Objective This study was designed to clear the quantitatively relationship between HBeAg and HBV DNA, and verify whether quantitative measurement of HBeAg could be used as a marker of viral replication in asymptomatic HBsAg-positive *** A cross-sectional, community-based survey was carried out in 12 communities of two counties.724 asymptomatic carriers with HBeAg-positive were divided into four groups by HBV DNA *** in groups Ⅰ (n =99), Ⅱ(n =79), Ⅲ (n =98) and Ⅳ (n =448) were reported HBV DNA levels of < 103 (PCR undetectable), 103 to 105 (PCR detectable), > 105 copies/ml(hybridization detectable) and > 107 copies/ml, *** The HBeAg levels have a good correlation with HBV DNA (r =0.765;P < 0.001) on a log *** mean log HBeAg (S/CO) of group Ⅰ, Ⅱ, Ⅲ, Ⅳ were 0.66 ±0.54,0.98 ±0.81,1.49 ±0.92,3.10 ± 0.89, *** mean log HBeAg level of group Ⅳ was significantly higher than that of the other *** best cut-off value of HBeAg in differentiating group Ⅳ from the other groups was 750 S/CO with a sensitivity of 97.3% and a specificity of 98.2%.Conclusion Quantitative measurement of HBeAg titres may be an easy and economical reference for HBV replication in HBV carriers.
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