Reduction of sex hormone levels in menopausal women is associated with several major health risks,including increased risk of Alzheimer’s disease(AD).Our previous published data showed that female AD patients express...
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Reduction of sex hormone levels in menopausal women is associated with several major health risks,including increased risk of Alzheimer’s disease(AD).Our previous published data showed that female AD patients express significantlty less brain endogenous estrogen than age-and gender-matched normal *** of endogenous estrogen causes
Anoctamin 1(ANO1 or TMEM16A)was cloned to be a candidate for ***1 is activated by intracellular Ca2+,which is also voltage ***1 is expressed in epithelia of salivary glands,pancreas,kidney,pulmonary airways,the retina...
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Anoctamin 1(ANO1 or TMEM16A)was cloned to be a candidate for ***1 is activated by intracellular Ca2+,which is also voltage ***1 is expressed in epithelia of salivary glands,pancreas,kidney,pulmonary airways,the retina,and sensory
Long-term memory formation requires post-transcriptional as well as transcriptional regulation in the *** map the landscape of the translatome and transcriptome during memory formation,we have performed ribosome profi...
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Long-term memory formation requires post-transcriptional as well as transcriptional regulation in the *** map the landscape of the translatome and transcriptome during memory formation,we have performed ribosome profiling and RNA-seq in mouse
Social dominance,as a fundamental and universal social behavior,is characterized by consistent winning in social *** individuals win more often in social confrontations,yet it is not simply brute strength and aggressi...
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Social dominance,as a fundamental and universal social behavior,is characterized by consistent winning in social *** individuals win more often in social confrontations,yet it is not simply brute strength and aggression that get an animal to the
Neurite initiation,the first step of neurite patterning,is the process by which the nascent neurite springs out from the post-mitotic neuronal soma and start *** found that this process is tightly correlated withthree...
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Neurite initiation,the first step of neurite patterning,is the process by which the nascent neurite springs out from the post-mitotic neuronal soma and start *** found that this process is tightly correlated withthree distinct actin distribution patterns that appear
Traumatic brain injury(TBI)is not only a leading cause for morbidity and mortality in young adults1,but also a leading cause of *** the seizure-inducing mechanisms of TBI is of the utmost importance because these seiz...
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Traumatic brain injury(TBI)is not only a leading cause for morbidity and mortality in young adults1,but also a leading cause of *** the seizure-inducing mechanisms of TBI is of the utmost importance because these seizures are often resistant
Gamma-aminobutyric acid(GABA)depolarizes primary afferent terminals of dorsal root ganglia(DRG)neurons through activation of Cl-permeable GABAA receptors in spinal cord but the physiological role of GABAA receptors in...
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Gamma-aminobutyric acid(GABA)depolarizes primary afferent terminals of dorsal root ganglia(DRG)neurons through activation of Cl-permeable GABAA receptors in spinal cord but the physiological role of GABAA receptors in peripheral terminals of DRG neurons remains *** this study,we investigated the role of peripheral GABAA receptors in
Humans empathize with others but not equally. I'll talk about our recent brain imaging research of racial in-group bias in empathic neural responses to others' suffering. These studies demonstrate the key role...
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Humans empathize with others but not equally. I'll talk about our recent brain imaging research of racial in-group bias in empathic neural responses to others' suffering. These studies demonstrate the key role of social intergroup relationship in emotional understanding and sharing, reveal the neural, cognitive, and genetic mechanisms underlying racial in-group bias in empathy, and illustrate how laboratory manipulations and life experiences can reduce the racial in-group bias in empathic neural responses. The implications of these studies will be discussed.
The anterior cingulate cortex(ACC)is thought to be key neural substrates underlying emotional *** pain-related conditioned place avoidance models(CPA),we observed that bilateral excitotoxic lesions of the ACC suppress...
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The anterior cingulate cortex(ACC)is thought to be key neural substrates underlying emotional *** pain-related conditioned place avoidance models(CPA),we observed that bilateral excitotoxic lesions of the ACC suppressed the formalin-induced CPA
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