作者：
Weidong LiBio-X Institutes
Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education)Shanghai Jiao Tong University
B-cell CLL/lymphoma 9(BCL9)was identified in a B-cell acute lymphoblastic leukemia cell line,and associated with tumor progression viaβ-catenin and Wnt signaling *** association studies suggested that BCL9 was also r...
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B-cell CLL/lymphoma 9(BCL9)was identified in a B-cell acute lymphoblastic leukemia cell line,and associated with tumor progression viaβ-catenin and Wnt signaling *** association studies suggested that BCL9 was also related to schizophrenia and bipolar
Dopamine(DA)transmission plays multiple roles in movement initiation and execution,reward signaling,cognition,and *** is well established that DA is released from terminals of dopaminergic neurons(DANs)in dorsal stria...
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Dopamine(DA)transmission plays multiple roles in movement initiation and execution,reward signaling,cognition,and *** is well established that DA is released from terminals of dopaminergic neurons(DANs)in dorsal striatum,nucleus accumbens,
Mesolimbic ventral tegmental area(VTA)dopaminergic neurons innervate nucleus accumbens(NAc)and cortical regions,and modulate body response to *** evidence demonstrates that dopaminergic neurons in VTA are directly
Mesolimbic ventral tegmental area(VTA)dopaminergic neurons innervate nucleus accumbens(NAc)and cortical regions,and modulate body response to *** evidence demonstrates that dopaminergic neurons in VTA are directly
Purpose:2-[[(1,1-dimethylethyl)oxidoimino]-methyl]-3,5,6-trimethylpyrazine(TBN)is a derivative of tetramethylpyrazine armed with a nitrone moiety,with dual functions of blocking Ca2+overload and scavenging free *** we...
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Purpose:2-[[(1,1-dimethylethyl)oxidoimino]-methyl]-3,5,6-trimethylpyrazine(TBN)is a derivative of tetramethylpyrazine armed with a nitrone moiety,with dual functions of blocking Ca2+overload and scavenging free *** we investigate whether TBN
Neural transplantation in Parkinson’s disease has been proven to be beneficial to the patients when *** we report a unique case that the patient received unilateral intra-putamen transplantation of ventral mesencepha...
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Neural transplantation in Parkinson’s disease has been proven to be beneficial to the patients when *** we report a unique case that the patient received unilateral intra-putamen transplantation of ventral mesencephalic tissues for twenty-four ***
Disrupted-in-Schizophrenia-1(DISC1)is considered to be a strong candidate susceptibility gene for schizophrenia and other affective *** our study,L100P homozygous and wild-type littermates were tested using a comprehe...
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Disrupted-in-Schizophrenia-1(DISC1)is considered to be a strong candidate susceptibility gene for schizophrenia and other affective *** our study,L100P homozygous and wild-type littermates were tested using a comprehensive behavioral battery,L100P mutant
Histone acetylation has been shown to play a crucial role in memory formation and histone deacetylase inhibitor sodium butyrate(Na B)can improve memory performance as well as rescue the neurodegeneration of several Al...
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Histone acetylation has been shown to play a crucial role in memory formation and histone deacetylase inhibitor sodium butyrate(Na B)can improve memory performance as well as rescue the neurodegeneration of several Alzheimer’s disease(AD)mouse models.
The mechanism underlying brain glucose hypometabolism and neurodegeneration in Alzheimer’s disease(AD)remains *** we find that brain glucose metabolism closely correlates with blood thiamine diphosphate(TDP)levels in...
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The mechanism underlying brain glucose hypometabolism and neurodegeneration in Alzheimer’s disease(AD)remains *** we find that brain glucose metabolism closely correlates with blood thiamine diphosphate(TDP)levels in AD ***
Neural biomechanics reveal that conversion law of form and energy of nervous tissue in the force- deformation and damage –process of electrical activity, and it play an important role in the development 、physiologic...
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Neural biomechanics reveal that conversion law of form and energy of nervous tissue in the force- deformation and damage –process of electrical activity, and it play an important role in the development 、physiological function and disease's process of the nervous system. Due to it has the specific, complex and multivariate structure and components, under the damage mechanical force, Nerve tissue has a diverse and individualized model of damage、pathological change 、 repair and prognosis, so, it would show the diversity clinical pain, The research of mechanism would provide the corresponding theoretical basis for clinical pain treatment.
A number of studies have shown that many of the mechanisms involved in the regulation of iron transport and utilization could be affected by the ageing *** has also been well documented that iron progressively accumul...
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A number of studies have shown that many of the mechanisms involved in the regulation of iron transport and utilization could be affected by the ageing *** has also been well documented that iron progressively accumulates in the brain with age and that oxidative
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