Objective: To review the epidemiologic and etiological features on patients with fungal keratitis at the Henan Eye Institute and Henan eye Hospital,Henan province in ***: A retrospective review of the records of 510 c...
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Objective: To review the epidemiologic and etiological features on patients with fungal keratitis at the Henan Eye Institute and Henan eye Hospital,Henan province in ***: A retrospective review of the records of 510 culture proven cases(510 eyes)of fungal keratitis diagnosed at the Henan Eye Institute and Henan eye Hospital from January 1,2014 to December 1,*** analytical parameters included demographic features,risk factors,seasonal variation,initial treatment time,and spectrum of fungi from the patients.
Objective: Low level laser irradiation(LLLI)modulate a set of biological effects in many types of cell,such as fibroblasts,keratinocytes and stem ***,no study reported the effects of LLLI on RPE *** aim of this study ...
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Objective: Low level laser irradiation(LLLI)modulate a set of biological effects in many types of cell,such as fibroblasts,keratinocytes and stem ***,no study reported the effects of LLLI on RPE *** aim of this study is to investigate whether LLLI could enhance the proliferation of RPE cells and increase the expression of RPE functional genes/proteins.
Objective To study the protective effect of salubrinal on H2O2-induced apoptosis of HLE-B3 and its ***: The cultured HLE-B3 was intervened with hydrogen peroxide(H2O2)Which created ERS model to oberserve the effect of...
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Objective To study the protective effect of salubrinal on H2O2-induced apoptosis of HLE-B3 and its ***: The cultured HLE-B3 was intervened with hydrogen peroxide(H2O2)Which created ERS model to oberserve the effect of Salburinal on *** cultured cells were interposed by different concentrations Salubrinal(10、15、20、25、35μmol/L)for *** the viability of cells was detected by cell counting kit-8(CCK-8)assay.
Backgrounds:The most important pathological event in retinal degenerative diseases is the loss of retinal retinal ganglion cells (RGCs).Lots of studies demonstrate the dental pulp stem cells (DPSCs) as self-renewing s...
Backgrounds:The most important pathological event in retinal degenerative diseases is the loss of retinal retinal ganglion cells (RGCs).Lots of studies demonstrate the dental pulp stem cells (DPSCs) as self-renewing stem cells,which can differentiate into neuronal lineages as well as RGCs in the retina,and express retinal neuronal markers just like glial fibrillary acidic protein (GFAP),polysialic acid-neural cell adhesion molecule (PSA-NCAM),rhodopsin in different *** animal models,the fate of the surviving cells were influenced by DPSCs transplanted into the brain differentiate into functional neurons or astrocytes.
Objective:To explore the function of paired box 6 (PAX6) and potential signaling pathways in corneal limbal stem cells (LSCs) lineage ***:PAX6 and p63 expression patterns were detected in mouse cornea at different emb...
Objective:To explore the function of paired box 6 (PAX6) and potential signaling pathways in corneal limbal stem cells (LSCs) lineage ***:PAX6 and p63 expression patterns were detected in mouse cornea at different embryonic ***,characterization of human corneal and skin epithelia were identified by PAX6 and K3,K12,K5 and ***,PAX6 and corneal markers were detected in patients with comeal-limbal ***,total RNA was isolated,and gene expression analysis was performed.
Purposes: To explore the role of CA V1 in glaucoma,and to study the cellular mechanism ***: It was an experimental ***,to explore whether CA V1 was involved in glaucoma,we initially investigated gene expression of CA ...
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Purposes: To explore the role of CA V1 in glaucoma,and to study the cellular mechanism ***: It was an experimental ***,to explore whether CA V1 was involved in glaucoma,we initially investigated gene expression of CA V1 in ONC glaucoma model by Q-PCR..Then cav1 knockout mice and cav1-shRNA systems were utilized to exam the role of CAV1 in the development of *** Retina Tomograph3(HRT3)was used to detect the glaucomatous damage of optic nerve head,and the number of retinal ganglion cells in cavl-shRNA treated animals was quantified.
Objective: To investigate the iris fixed intraocular lens(Verisyse iris-fixated phakic intraocular lens,Verisyse PIOL)after long-term decline in cases of corneal endothelial ***: A retrospective analysis conducted sin...
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Objective: To investigate the iris fixed intraocular lens(Verisyse iris-fixated phakic intraocular lens,Verisyse PIOL)after long-term decline in cases of corneal endothelial ***: A retrospective analysis conducted since 2005 Verisyse PIOL implantation keep track of follow-up,12 patients(6-10 years)an average of 8 years of corneal endothelial cell density(Endothelial cell density,ECD)4 in the same situation and after surgery sets of data were ***: All patients were followed up for 8 years 3 PIOL dislocation into the anterior chamber,the remaining 21 lines ECD measured statistically significant difference compared with 4 years after surgery(P<0.01).Conclusion: Verisyse PIOL implantation forward corneal endothelial cell count decreased,for the prevention of corneal endothelial decompensation,the patient is asked to regular follow-up should be closely monitored comeal endothelial cells,and to take effective measures for treatment.
Purpose: Bone marrow mesenchymal stem cells(MSCs)could be differentiated into neuron-like cells in vitro,but whether the differentiated cells could establish an effective neural signal transduction network is *** sign...
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Purpose: Bone marrow mesenchymal stem cells(MSCs)could be differentiated into neuron-like cells in vitro,but whether the differentiated cells could establish an effective neural signal transduction network is *** signal transduction is mainly based on the polarization of ***6 is the main composition protein of cell polarization compound PARD6/PARD3/*** we aimed to investigate the expression of PARD6 during the process of MSCs differentiated into neuron-like cell and observe the polarization of neuron-like cell differentiated from *** addition,we screened a microRNA family let-7 by bioinformatics,which might regulate the expression of ***,we explored whether let-7 was involved in the differentiation of MSCs into neuron-like cells by regulating the expression of PARD6.
Aim: To investigate the effect of minocycline on the injury of glutamate-induced rat retinal neural cells via p38MAPK signaling ***: Primary cultures of retinal neural cells were prepared from neonatal SD *** cells we...
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Aim: To investigate the effect of minocycline on the injury of glutamate-induced rat retinal neural cells via p38MAPK signaling ***: Primary cultures of retinal neural cells were prepared from neonatal SD *** cells were divided into normal control group(groupA),glutamate group(glutamate 1 mmol/L,groupB),minocycline-treating group(glutamate 1 mmol/L minocycline20 μmol/L,groupC),SB203580 interventional group(glutamate 1 mmol/L + SB203580 10pmol/L,groupD)and Combined interventional group(glutamate 1 mmol/L + minocyline20 μtmol/L+ SB203580 10pmol/L,groupE).MTT assays was employed to assess *** orange/ethidium bromide(AO/EB)double fluorescent staining to observe morphology and cell *** of p-p38MAPK,BCL-2 and BAX were observed respectively by IHC and Westem Blot.
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