CKIP-1 is a negative regulator of osteoblastic bone *** the past years,CKIP-1 has been found to negatively correlate with bone formation in aged postmenopausal women in our clinical ***,we have identified a cross-spec...
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CKIP-1 is a negative regulator of osteoblastic bone *** the past years,CKIP-1 has been found to negatively correlate with bone formation in aged postmenopausal women in our clinical ***,we have identified a cross-species CKIP-1 siRNA sequence(human,rat,mouse,rhesus)with osteogenic potential(conditional accept by Arthritis&Rheumatism).Further,
April 12 Thursday09:00-21:00 Registration18:30-19:30 Dinner APril 13 Friday08:00-08:15 Group Picture08:30-09:00 Opening Ceremony09:00.10:55 SESSIoN I ASBMR Delegate Section Session Chairs:Jane *** and Paul MacDonald09...
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April 12 Thursday09:00-21:00 Registration18:30-19:30 Dinner APril 13 Friday08:00-08:15 Group Picture08:30-09:00 Opening Ceremony09:00.10:55 SESSIoN I ASBMR Delegate Section Session Chairs:Jane *** and Paul MacDonald09:00-09:40 Control of Bone Mass by Novel Runx2 Regulatory Pathways---Jane ***(U.S.A.)09:40-10:20 Vitamin D receptor target genes and coactivators in osteoblasts---Paul MacDonald(U.S.A.)
1,25-dihydroxyvitamin D3(1,25(OH)D)is the bioactive hormone of the vitamin D endocrine *** functions through the vitamin D receptor(VDR)to selectively regulate genetic networks in osteoblasts that impact osteoblas...
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1,25-dihydroxyvitamin D3(1,25(OH)D)is the bioactive hormone of the vitamin D endocrine *** functions through the vitamin D receptor(VDR)to selectively regulate genetic networks in osteoblasts that impact osteoblast proliferation,differentiation,and *** of the long-term goals of our research group has been to examine novel transcriptional targets of 1,25(OH)D and VDR in osteoblasts and explore the role(s)of these
Aging is associated with a reduction in bone marrow MSC numbers and a deficiency in the supportive bone marrow microenvironment that augments the bone formation *** decrease in the resident MSC population with osteoge...
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Aging is associated with a reduction in bone marrow MSC numbers and a deficiency in the supportive bone marrow microenvironment that augments the bone formation *** decrease in the resident MSC population with osteogenic potential within the bone marrow may be the most important factor responsible for reduced bone formation and the subsequent increase in bone fragility with advancing *** regeneration by
Multiple myeloma(MM)is one of the most frequent cancers that affect skeleton and induces osteolytic *** cell-cell interactions among MM tumor cells andtheir rnicroenvironment are essential for tumor growth,survival an...
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Multiple myeloma(MM)is one of the most frequent cancers that affect skeleton and induces osteolytic *** cell-cell interactions among MM tumor cells andtheir rnicroenvironment are essential for tumor growth,survival and MM-induced osteolytic *** marrow stromal cells(BMSCs)are key players in the microenvironmental support of MM cell growth and bone *** form of X-box binding protein-1
Osteoporosis is a multifactorial disease with many contributing factors leading to bone loss caused by an age-related decrease in the number and activity of osteoblasts and further exacerbated by hormonal changes lead...
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Osteoporosis is a multifactorial disease with many contributing factors leading to bone loss caused by an age-related decrease in the number and activity of osteoblasts and further exacerbated by hormonal changes leading to increased osteoclast bone *** discovery of the master transcription factor,Runx2 that is essential for commitment and differentiation of mesenchymal stem cells(MSCs)to osteoblasts and bone
Expressed in branchial arches and osteoblast-lineage ceils,special AT-rich sequence—binding protein(SATB2)is responsible for preventing craniofacial abnormalities and defects in osteoblast *** this study,we transplan...
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Expressed in branchial arches and osteoblast-lineage ceils,special AT-rich sequence—binding protein(SATB2)is responsible for preventing craniofacial abnormalities and defects in osteoblast *** this study,we transplanted SATB2-overexpressing adult stem cells genetically double-labeled with bone sialoprotein(asP)promoter-driven luciferase and b-actin promoter-driven enhanced green fluorescent protein into mandibular bone
Neruological deficit due to osteoporotic vertebral fracture is severe disturbance for *** have performed surgical intervention,constructing vertebral column with anterior or posterior ***,we report retrospective radio...
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Neruological deficit due to osteoporotic vertebral fracture is severe disturbance for *** have performed surgical intervention,constructing vertebral column with anterior or posterior ***,we report retrospective radiological study on our postoperative cases with discussion of *** two cases(34 female,8 male:mean age of 75.5 yrs old)were studied ***
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