检索结果-内蒙古大学图书馆

您好，读者！请登录

内蒙古大学图书馆

首页
概况
党建
资源
服务
科研支持
- 论文收录引用证明
- 科技查新
知识产权
档案馆
帮助

咨询与建议

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

您的常用邮箱：*

您的手机号码：*

问题描述：

当前已输入0个字，您还可以输入200个字

全部搜索
期刊论文
图书
学位论文
标准
纸本馆藏
外文资源发现
数据库导航
超星发现

高级检索

时间限定

出版年份：

文献类型

图书期刊文献学位论文多媒体

馆藏选择

电子馆藏纸本馆藏

核心期刊

全部期刊 SCI 收录期刊 SSCI 收录期刊 EI 收录期刊 CSCD 收录期刊 CSSCI 收录期刊

语言

中文英文

文献类型

期刊文献图书学位论文标准纸本馆藏

帮助

文字说明：

T=题名（书名、题名），A=作者（责任者），K=主题词，P=出版物名称，PU=出版社名称，O=机构（作者单位、学位授予单位、专利申请人），L=中图分类号，C=学科分类号，U=全部字段，Y=年（出版发行年、学位年度、标准发布年）

检索规则说明：

AND代表“并且”；OR代表“或者”；NOT代表“不包含”；(注意必须大写,运算符两边需空一格)

检索范例：

范例一：(K=图书馆学 OR K=情报学) AND A=范并思 AND Y=1982-2016
范例二：P=计算机应用与软件 AND (U=C++ OR U=Basic) NOT K=Visual AND Y=2011-2016

分类表

所选分类

>> <<

限定检索结果

文献类型

59 篇 会议

馆藏范围

59 篇 电子文献
0 种 纸本馆藏

日期分布

学科分类号

39 篇 理学
- 38 篇 生物学
- 1 篇 物理学
- 1 篇 化学
25 篇 农学
- 24 篇 作物学
- 1 篇 兽医学
18 篇 工学
- 6 篇 化学工程与技术
- 5 篇 生物工程
- 4 篇 光学工程
- 4 篇 仪器科学与技术
- 2 篇 机械工程
- 2 篇 材料科学与工程（可...
- 1 篇 电子科学与技术（可...
- 1 篇 计算机科学与技术...
- 1 篇 轻工技术与工程
- 1 篇 生物医学工程（可授...
11 篇 医学
- 8 篇 基础医学(可授医学...
- 7 篇 药学(可授医学、理...
- 2 篇 临床医学

主题

2 篇 分辨率
2 篇 三维结构
1 篇 visualizing phag...
1 篇 biophysical and ...
1 篇 secretase assemb...
1 篇 体外组装
1 篇 mpi
1 篇 免疫原性
1 篇 复合物
1 篇 电子显微学
1 篇 ryr
1 篇 the gpu paralliz...
1 篇 等价线
1 篇 背散射电子成像
1 篇 病毒样颗粒
1 篇 atomic structure...
1 篇 收集策略
1 篇 image
1 篇 fourier
1 篇 exosome

机构

5 篇 清华大学
5 篇 中国科学院生物物...
4 篇 中科院生物物理所
3 篇 tsinghua univers...
3 篇 北京生命科学研究...
2 篇 harvard medical ...
2 篇 university of ca...
2 篇 school of life s...
2 篇 institute of bio...
2 篇 mrc laboratory o...
2 篇 中山大学
2 篇 中国科学技术大学
2 篇 湖南师范大学
1 篇 university of te...
1 篇 center for struc...
1 篇 department of bi...
1 篇 mrc-lmb
1 篇 national key lab...
1 篇 the center for b...
1 篇 pittsburgh cente...

作者

5 篇 fei sun
4 篇 孙飞
3 篇 chuangye yan
3 篇 xueming li
3 篇 何万中
3 篇 jianguo zhang
3 篇 张建国
3 篇 gang ji
2 篇 hongwei wang
2 篇 yigong shi
2 篇 lingyun zhao
2 篇 wei ding
2 篇 rui zhou
2 篇 张勤奋
2 篇 guanghui yang
2 篇 hongrong liu
2 篇 李喜霞
2 篇 z.hong zhou
2 篇 lei sun
2 篇 yu chen

语言

45 篇 英文
14 篇 中文

检索条件"任意字段=第四届全国冷冻电子显微学与结构生物学专题研讨会"

共 59 条记录，以下是51-60 订阅

全选清除本页清除全部题录导出标记到"检索档案"

详细简洁

排序：

Structure insights into urea amidolyase by using single particle electron microscopy

Structure insights into urea amidolyase by using single part...

引用

第四届全国冷冻电子显微学与结构生物学专题研讨会

作者：朱莉 Yan Ouyang Jing Zhao Yang Liu Yifang Li Song Xiang Yi Wu 兰州大学 School of Life Science Lanzhou University Institute for Nutritional Sciences Shanghai Institutes for Biological SciencesChinese Academy of Sciences

Urea amidolyase(UA),widely distributed in fungi and bacteria,is essential for catalyzing the conversion of urea to ammonium,making the final product as the main nitrogen source in these *** comprises both the urea car... 详细信息

关键词： Structure insights into urea amidolyase by using single particle electron microscopy

来源：评论

学校读者我要写书评

暂无评论

A Realistic 3D Phantom for Electron Tomography

A Realistic 3D Phantom for Electron Tomography

引用

第四届全国冷冻电子显微学与结构生物学专题研讨会

作者：万晓华 Sébastien Phan Albert Lawrence Ziying Zhou Ruijuan Chen Fa Zhang Mark Ellisman 中科院计算所 National Center for Microscopy and Imaging Research University of California Beijing Institute of Technology School of electronic and information engineering Tianjin Polytechnic University

＜正＞Electron tomography（ET）is to generate three-dimensional（3D）representations of biological structures,with a nanometer resolution.3D reconstructions of the samples are derived from a tilt-series acquired at different tilting angles by means of a 2D alignment and 3D reconstruction ***,the missing wedge problem

关键词：

来源：评论

学校读者我要写书评

暂无评论

ICON, a 3D-reconstruction algorithm using compressed sensing approach and its application in electron tomography

ICON, a 3D-reconstruction algorithm using compressed sensing...

引用

第四届全国冷冻电子显微学与结构生物学专题研讨会

作者： Yuchen Deng Yu Chen Yan Zhang Fa Zhang 孙飞 National Key Laboratory of Biomacromolecules Institute of BiophysicsChinese Academy of Sciences University of Chinese Academy of Sciences National Key Laboratory of Intelligent Information Processing Institute of Computing TechnologyChinese Academy of Sciences 中国科学院生物物理研究所

＜正＞Cryo-electron tomography（ET）plays an important role in revealing biological structures,ranging from macromolecule scale to subcellular *** acquiring series of pictures with different angular assignment,one per...

关键词：

来源：评论

学校读者我要写书评

暂无评论

Cryo-EM Structure of influenza Virus RNA Polymerase Complex at 4.3? Resolution

Cryo-EM Structure of influenza Virus RNA Polymerase Complex ...

引用

第四届全国冷冻电子显微学与结构生物学专题研讨会

作者：刘迎芳 Shenghai Chang Dapeng Sun Huanhuan Liang Jia Wang Jun Li Lu Guo Xiangli Wang Chengcheng Guan Bhargavi M.Boruah Lingmin Yuan Feng Feng Mingrui Yang Lulan Wang Yao Wang Justyna Wojdyla Lanjuan Li Jiawei Wang Meitian Wang Genhong Cheng Hong-Wei Wang 中国科学院生物物理研究所 Tsinghua University University of California 3Swiss Light Source Paul Scherrer Institute Zhejiang University

＜正＞The influenza virus genome is transcribed and replicated by the heterotrimeric RNAdependent RNA polymerase（RdRP）,which compriseses subunits PA,PB1 and *** extensively studied,the underlying mechanism of the RdRP complex is still unclear,largely owing to the lack of atomic resolution structural information on

关键词：

来源：评论

学校读者我要写书评

暂无评论

Intra-and inter-neuronal Localization of Herpes Virus Revealed by Correlative Light and Electron Microscopy

Intra-and inter-neuronal Localization of Herpes Virus Reveal...

引用

第四届全国冷冻电子显微学与结构生物学专题研讨会

作者：刘云涛 Sakar Shivakoti Changlu Tao Fan Jia Bin Zhang Fuqiang Xu Pakming Lau Z.Hong Zhou Guoqiang Bi Center for Integrative Imaging Hefei National Laboratory for Physical Sciences at the Microscale CAS Center for Excellence in Brain Science and School of Life SciencesUniversity of Science and Technology of China Wuhan Institute of Physics and Mathematics Chinese Academy of Sciences CAS Key Laboratory of Brain Function and Disease and School of Life SciencesUniversity of Science and Technology of China

The highly specific spread of alpha-herpes virus in nervous system has been widely used in tracing neuronal connections and ***,the exact process and mechanism through which the virus assembles in the neuron and sprea... 详细信息

关键词： Intra-and inter-neuronal Localization of Herpes Virus Revealed by Correlative Light and Electron Microscopy

来源：评论

学校读者我要写书评

暂无评论

The human dendritic cell receptor DEC205:structure and function

The human dendritic cell receptor DEC205:structure and funct...

引用

第四届全国冷冻电子显微学与结构生物学专题研讨会

作者： Longxing Cao Xiangyi Shi Haishuang Chang Qinfen Zhang Wah Chiu 何勇宁 National Center for Protein Science Institute of Biochemistry and Cell BiologyShanghai Institutes for Biological SciencesChinese Academy of Sciences State Key Laboratory of Biocontrol School of Life SciencesSun Yat-sen University National Center for Macromolecular Imaging Verna and Marrs Mclean Department of Biochemistry and Molecular BiologyBaylor College of Medicine 中国科学院上海生命科学研究院

＜正＞Immune receptors play important roles in recognizing and presenting self-and non-self antigens in immune *** mannose receptor family members are largely expressed on the surface of immune cells such as macrophag...

关键词：

来源：评论

学校读者我要写书评

暂无评论

Structures of HIV-1 Capsid Assembly and in Complex with Host Cell Factors

Structures of HIV-1 Capsid Assembly and in Complex with Host...

引用

第四届全国冷冻电子显微学与结构生物学专题研讨会

作者： Gongpu Zhao Chuang Liu Juan R.Perilla Jiying Ning Xueming Li Shenping Wu Randall T. Schirra Jr. Angela M.Gronenborn Yifan Cheng Chris Aiken Tatyana Polenova Klaus Schulten 章佩君 Department of Structural Biology University of Pittsburgh School of Medicine Pittsburgh Center for HIV Protein Interactions Department of Physics and Beckman Institute University of Illinois at Urbana-Champaign School of Life Sciences Tsinghua University Department of Biochemistry and Biophysics University of California Department of Pathology Microbiology and ImmunologyVanderbilt University School of Medicine Department of Chemistry and Biochemistry University of Delaware

＜正＞The human immunodeficiency virus 1（HIV-1）mature capsid protein（CA）contains two structural domains that are connected by a flexible linker and assembles into a distinct cone shaped capsid that encloses the vi...

关键词：

来源：评论

学校读者我要写书评

暂无评论

Structure of human γ-secretase

Structure of human γ-secretase

引用

第四届全国冷冻电子显微学与结构生物学专题研讨会

作者： Chuangye Yan Xiaochen Bai Linfeng Sun Guanghui Yang Lingyun Zhao Rui Zhou Xiaoyuan Zhou Tian Xie Yanyu Zhao Shenjie Wu Peilong Lu Dan Ma Xueming Li Sjors H.W.Scheres 施一公 Center for Structural Biology School of Life SciencesTsinghua University MRC Laboratory of Molecular Biology Cambridge Biomedical Campus 清华大学

Alzheimer’s disease, characterized by formation of-amyloid plaque in patient brain, is closely associated with-secretase. Amyloid precursor protein（APP） is processed by-and-secretases in the extracellular space to produce a series of-amyloid peptides（A） exemplified by A 42 and A 40. Among all A s, A 42 is particularly prone to aggregation, resulting in formation of-amyloid plaque. The human-secretase is a membrane-embedded protease complex that comprises four components presenilin 1（PS1）, Pen-2, Aph-1, and nicastrin. We previously determined two cryo-EM structures of human-secretase at 4.5 and 4.3 ? resolution. The first cryo-EM structure, determined in the presence of amphipols, allowed visualization of the intact human-secretase for the first time, with identification of 19 transmembrane segments（TMs） and a protease-like extracellular domain（ECD） from nicastrin [Lu et al, Nature 512, 166-170（2014）]. But the resolution range of EM densities in the transmembrane region was too low（5-7 ?） to allow assignment of specific TMs to the four components. A subsequent crystal structure of eukaryotic nicastrin allowed improvement of the human nicastrin model and suggested an arrangement of the 19 TMs [Xie et al, PNAS 111, 13349-13354（2014）]. The second cryo-EM structure, with a resolution range of 4-5 ? in the transmembrane region, confirmed this arrangement by conclusively assigning all 20 TMs to the four components and revealed presence of one additional TM [Sun et al, PNAS, published online（2015）]. Importantly, the second cryo-EM structure of human-secretase was solved in the detergent digitonin, thus eliminating the concern that the first structure might represent an artifact in harsh conditions. In this presentation, I will describe the first atomic structure of human-secretase at 3.4 ? resolution. This structure allows visualization of atomic details of all four components of human-secretase for the first time and reveals important functional insights.

关键词：

来源：评论

学校读者我要写书评

暂无评论

Structural basis for the long range allosteric regulation and high ion conductance of the ryanodine receptor RyR1

Structural basis for the long range allosteric regulation an...

引用

第四届全国冷冻电子显微学与结构生物学专题研讨会

作者： Zhen Yan Xiaochen Bai Chuangye Yan Jianping Wu Zhangqiang Li Sjors H.W.Scheres Yigong Shi 颜宁 State Key Laboratory of Bio-membrane and Membrane Biotechnology Ministry of Education Key Laboratory of Protein ScienceCenter for Structural BiologyTsinghua-Peking Joint Center for Life SciencesSchool of Life Sciences and School of MedicineTsinghua University MRC Laboratory of Molecular Biology Cambridge Biomedical Campus 清华大学

Ryanodine receptors(RyRs) mediate rapid release of calcium ions from sarcoplasmic/endoplasmic reticulum and play a pivotal role in the excitation-contraction coupling of skeletal and cardiac muscles. RyRs represent the largest known ion channels and are homotetramers, with each subunit comprising approximately five thousand residues. We determined the structure of the full-length rabbit RyR1 in complex with the modulator FKBP12 at an overall resolution of 3.8 ?, using single particle electron cryomicroscopy. Near-atomic resolution is achieved at the channel domain and its adjoining domains in the cytoplasmic region and resolves 70 percent of the 2.2 million Dalton molecular mass of Ry R1. The carboxyl terminal fragment(residues 4545-5037) exhibits the voltage-gated ion channel(VGIC) superfamily fold. An outer site formed by the side chains of Asp4899/Glu4900 and an inner site surrounded by carbonyl oxygen atoms may serve as the Ca binding sites along the selectivity filter(SF) vestibule. A highly electronegative hairpin loop connecting S5 and the pore helix is positioned above the entrance to the SF vestibule. The four elongated S6 segments form a right-handed helical bundle that closes the ion-conducting pore at the cytoplasmic border of the membrane. The cytoplasmic vestibule of the pore is enriched with Glu and Asp residues, which likely modulate ion conductance. The S6 segment is followed by a carboxyl-terminal domain(CTD) which contains a previously uncharacterized zinc finger motif. The sequences between S2 and S3 segments fold into a cytoplasmic domain which we name the VSC domain. In addition to the channel domain, structural models were built for three previously uncharacterized major domains: the Central domain, the Handle domain, and the Helical domain. These three domains, all displaying the armadillo repeat fold, together with the amino-terminal domain, constitute a network of superhelical scaffold at the cytoplasmic side. Allosteric regulation of the p

关键词：

来源：评论

学校读者我要写书评

暂无评论

没有更多数据了...

全选清除本页清除全部题录导出标记到“检索档案”

共6页 << < 1 2 3 4 5 6 > >>

检索报告对象比较合并检索0

隐藏清空

合并搜索

回到顶部

执行限定条件

内容：

评分：

请选择保存的检索档案：

请选择收藏分类：

订阅名称：

通借通还

温馨提示：

图书名称：

借书校区：

取书校区：

手机号码：

邮箱地址：

一卡通帐号：

电话和邮箱必须正确填写，我们会与您联系确认。

联系人：

所在院系：

联系邮箱：

联系电话：

内蒙古自治区呼和浩特市赛罕区大学西街235号邮编: 010021

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：