It is widely recognized that systems biology is very important for understanding the functions of a cellular *** approaches have now been proposed to analyzing the performance of a cellular ***,systems biology still f...
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It is widely recognized that systems biology is very important for understanding the functions of a cellular *** approaches have now been proposed to analyzing the performance of a cellular ***,systems biology still faces great challenges,for example,with the number increment of chemical elements in a
Adverse drug reactions(ADRs) occur frequently in patients with *** is also a crucial factor that causes drug failure in clinical trials of drug ***,we will briefly introduce our recent works in mechanistic understandi...
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Adverse drug reactions(ADRs) occur frequently in patients with *** is also a crucial factor that causes drug failure in clinical trials of drug ***,we will briefly introduce our recent works in mechanistic understanding and prediction of ADRs.A gene-regulation network model of about 20,000 gene-ADR relations was
There is a growing interest in miRNA-miRNA synergistic regulations and the relationships between miRNAs and Subpathway regulated by the miRNA to understand the mechanisms of complex *** diseases are affected by severa...
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There is a growing interest in miRNA-miRNA synergistic regulations and the relationships between miRNAs and Subpathway regulated by the miRNA to understand the mechanisms of complex *** diseases are affected by several miRNAs rather than a single miRNA. So,it is a challenge to identify miRNA
Transcriptome is the sum of all transcripts in a given cell under a defined *** is determined by several lines of information, which includes(1) chromosome organization and replication timing;(2) gene organization and...
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Transcriptome is the sum of all transcripts in a given cell under a defined *** is determined by several lines of information, which includes(1) chromosome organization and replication timing;(2) gene organization and transcription timing;(3) gene structure and splicing machinery(such as major and minor spliceosomes;(4) Coupling of splicing and export;and(5) mRNA maturation and
Most important agronomic traits of crops, such as crop yield and quality,are complex traits affected by multiple genes with gene×gene interaction as well as gene×environment ***,the genetic properties of tra...
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Most important agronomic traits of crops, such as crop yield and quality,are complex traits affected by multiple genes with gene×gene interaction as well as gene×environment ***,the genetic properties of traits can be revealed by partitioning the total variation into component variation due to specific genetic *** recent advances in molecular genotyping and high-throughput technology,great opportunity
Schizophrenia is a complicated disease that is currently diagnosed by behaviors or external *** is argued that Schizophenia is a really comprised of multiple *** addition,there are complications that acompany treatmen...
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Schizophrenia is a complicated disease that is currently diagnosed by behaviors or external *** is argued that Schizophenia is a really comprised of multiple *** addition,there are complications that acompany treatments to this disease,like Tardive Dyskinesia,which make treatment difficult as *** needs to be a better
1 Introduction DNA methylation,as an inartificial and inheritance epigenetic event,affects biological phenotype by inhibiting gene expression without changing the DNA *** quantification of methylation difference acros...
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1 Introduction DNA methylation,as an inartificial and inheritance epigenetic event,affects biological phenotype by inhibiting gene expression without changing the DNA *** quantification of methylation difference across large numbers of samples and the identification of sample-specificity are important in genomic function analysis,and may provide an important reference for
This paper is focused on the analysis of the protein primary and spatial structure and their application. The database of protein primary structure can be considered as a library with commas. From this point,we discus...
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This paper is focused on the analysis of the protein primary and spatial structure and their application. The database of protein primary structure can be considered as a library with commas. From this point,we discuss the semantic analysis for this library,including:the construction of word library and dictionary;the relationship database of words and
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