The International Symposium for Chinese Medicinal Chemists(iscmc) is a prestigious conference for global Chinese researchers and scientists in the field,which has been set up and organized once every other year sinc...
The International Symposium for Chinese Medicinal Chemists(iscmc) is a prestigious conference for global Chinese researchers and scientists in the field,which has been set up and organized once every other year since 1998.11 International Symposium for Chinese Medicinal Chemists 2018(iscmc2018) will be held on August 24-26,2018,in The Henan Yellow River Yingbin Grand Hotel of
Chemical probes are very useful tools for the investigation of drug target and mechanism *** this presentation a series of probes formed from natural products were used for the finding proteins as the target of antivi...
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Chemical probes are very useful tools for the investigation of drug target and mechanism *** this presentation a series of probes formed from natural products were used for the finding proteins as the target of antiviral drugs.
Heterocycles have been well known as life-saving *** efficient synthesis and rapid derivation of Bioactive heterocyclic compounds is very important for drug *** tandem or multicomponent reactions have been developed f...
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Heterocycles have been well known as life-saving *** efficient synthesis and rapid derivation of Bioactive heterocyclic compounds is very important for drug *** tandem or multicomponent reactions have been developed for the synthesis of bioactive heterocyclic compounds.
Computer Aided Drug Design(CADD) has been formally used in the industry for more than30 *** the recent advancement in hardware,software and AI,computational technologies have evolved to play an increasingly important ...
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Computer Aided Drug Design(CADD) has been formally used in the industry for more than30 *** the recent advancement in hardware,software and AI,computational technologies have evolved to play an increasingly important role in the pharmaceutical *** from the start,Hengrui has embraced the technologies and integrated them
AMO 579,a potent and selective PDEIOA inhibitor,was identified as Amgen's first generation clinical *** this presentation,we will describe a novel series of structurally distinct azetidine-containing PDEIOA inhibi...
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AMO 579,a potent and selective PDEIOA inhibitor,was identified as Amgen's first generation clinical *** this presentation,we will describe a novel series of structurally distinct azetidine-containing PDEIOA inhibitors as potential back-up molecules to AMO *** will detail the program flow scheme,evolution of the SAR,and especially
As the name suggests,non-enzymatic proteins refer to proteins without enzymatic activity such as numerous receptors,ion channels,protein-protein interactions,and so *** involving various tumor targets,the deep study o...
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As the name suggests,non-enzymatic proteins refer to proteins without enzymatic activity such as numerous receptors,ion channels,protein-protein interactions,and so *** involving various tumor targets,the deep study of these non-enzymatic proteins is of high significance for cancer *** key to understanding the biological processes of
Total synthesis of(±)-wuweizisu C was *** vitro studies indicated that wuweizisu C demonstrated good protective activity against acetaminophen induced liver cell damage,which is superior to the clinical drug bicy...
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Total synthesis of(±)-wuweizisu C was *** vitro studies indicated that wuweizisu C demonstrated good protective activity against acetaminophen induced liver cell damage,which is superior to the clinical drug bicyclol(Table 1).
The success rate of mechanism-based drug discovery depends on the drug ***,small-molecule drug regulates the function of targets by occupying the active ***,this kind of regulating mechanism cannot be applied to these...
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The success rate of mechanism-based drug discovery depends on the drug ***,small-molecule drug regulates the function of targets by occupying the active ***,this kind of regulating mechanism cannot be applied to these nonenzymic proteins,which are recognized as undruggable *** regulating the concentration
<正>The international development of Chinese medicine faces opportunities and challenges:to ensure the safety and efficacy of clinical efficacy in modernization,to control the stability of products in industrializat...
<正>The international development of Chinese medicine faces opportunities and challenges:to ensure the safety and efficacy of clinical efficacy in modernization,to control the stability of products in industrialization,and to make the quality control strategy reasonable and *** quality of Chinese medicine is a key scientific issue that affects the clinical efficacy,industrial development and international development of Chinese *** 2010,Macau
Acute or chronic inflammation is involved in the development and/or progression of a variety of diseases,including sepsis,acute lung injury,atherosclerosis,pulmonary inflammatory diseases,diabetic complications and **...
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Acute or chronic inflammation is involved in the development and/or progression of a variety of diseases,including sepsis,acute lung injury,atherosclerosis,pulmonary inflammatory diseases,diabetic complications and ***-expression of pro-inflammatory cytokines and macrophage infiltration are generally observed and play a significant role in the
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