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检索条件"任意字段=第11届世界华人药物化学研讨会(ISCMC2018)"
414 条 记 录,以下是381-390 订阅
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Regulation mechanism of G9a on glioma and its application as drug targets
Regulation mechanism of G9a on glioma and its application as...
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11世界华人药物化学研讨会iscmc 2018
作者: Lanlan Zang Shukkoor Muhammed Kondengaden Xueyuan Heng Central Laboratory and Key Laboratory of Neurophysiology Linyi People's HospitalShandong University Department of Medicinal Chemistry Key Laboratory of Chemical Biology(Ministry of Education)School of Pharmaceutical SciencesShandong University Chemistry Department and Center for Diagnostics and Therapeutics Georgia State University
Neurogliotna is a disease with high incidence and short survival,the epigenetic phenomena such as abnormal histone modifications and so on are closely related to the occurrence and development of *** are few related s... 详细信息
来源: 评论
N19 exerts anti-leukemic effects on genetically different AMLcell lines by promoting cell differentiation and apoptosis
N19 exerts anti-leukemic effects on genetically different AM...
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11世界华人药物化学研讨会iscmc 2018
作者: Shehung Chan Hsushan Huang Jihhwa Guh School of Pharmacy Taiwan University Department of Cosmetic Science Providence University The Ph.D.Program for Cancer Biology and Drug Discovery
Leukemia,the disease of hematological malignancies,is characterized by clonal expansion of hematopoietic cells that are uncontrolled proliferation,decreased cell death as well as blocked *** promyelocytic leukemia(AP... 详细信息
来源: 评论
Synthesis and Pinl inhibitory activity of thiazole derivatives
Synthesis and Pinl inhibitory activity of thiazole derivativ...
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11世界华人药物化学研讨会iscmc 2018
作者: Lifei Du Kaiyue Liu Hailong Zhao Jing Jin Guonan Cui Xiaoguang Chen Bailing Xu Institute of Materia Medica Chinese Academy of Medical Sciences & Peking Union Medical College
Pin1(Protein interacting with NIMA1) is a peptidyl proly1 cis-trans isomerase(PPIase) which specifically catalyzes the conformational conversion of the amide bond of pSer/Thr-Pro motifs in its substrate proteins. ... 详细信息
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Establishment of screening platform for small molecular inhibitors of BRD4 and screening and activity evaluation of inhibitors
Establishment of screening platform for small molecular inhi...
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11世界华人药物化学研讨会iscmc 2018
作者: Dandan Shen Shuai Wang Qimeng Song Yichao Zheng Hongmin Liu School of Pharmaceutical Sciences Zhengzhou University Collaborative Innovation Center of New Drug Research and Safety Evaluation
BRIM has two BRD domain which can recognize the histone acetylation modification,mediating interaction of ***4 is abnormal expression in a variety of tumors,including almost all kinds of blood tumors and solid *** inh... 详细信息
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Total synthesis of jolkinolide analogues as potential anti-cancer agents
Total synthesis of jolkinolide analogues as potential anti-c...
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11世界华人药物化学研讨会iscmc 2018
作者: Ke Wang Juancheng Yang Xiaoming Wu Dayong Zhang Yangchang Wu Department of Medicinal Chemistry China Pharmaceutical University Center for Drug Discovery China Pharmaceutical University Graduate Institute of Natural Products Kaohsiung Medical University Research Center for Natural Products & Drug Development Kaohsiung Medical University
Jolkinolides are a series naturally ent-abietane diterpenes with potent antitumor *** isolated from genusEuphorbia,a Traditional Chinese Medicine(TCM),which is used for treating "dampness toxin",swollen so... 详细信息
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Anti-histone deacetylase and reversing cisplatin resistance of adamantane based N-hydroxypropenamides in lung cancer cells
Anti-histone deacetylase and reversing cisplatin resistance ...
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11世界华人药物化学研讨会iscmc 2018
作者: Xuefei Bao Yuhong Sun Changshun Bao Jiayu Zhang Shenglan Zou Jingyu Yang Chunfu Wu Lihui Wang Guoliang Chen Key Laboratory of Structure-Based Drugs Design and Discovery of Ministry of Education Shenyang Pharmaceutical University Department of Pharmacology Shenyang Pharmaceutical University Benxi Institute of Pharmaceutical Research Shenyang Pharmaceutical University
The expression level of P-gp increased with the evolution of NSCLC,which was a consequence of the acquired ***,several studies had shown,except P-gp,the aberrant epigenetic regulations also played a crucial role in ci... 详细信息
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Design,synthesis and in vitro activity of novel triazine-based LSD1 inhibitors
Design,synthesis and in vitro activity of novel triazine-bas...
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11世界华人药物化学研讨会iscmc 2018
作者: Ying Liu Longfei Zhao Jianjia Liang Zhusong Cao Xiaojing Li Le Yang Bo Wang Fengzhi Suo Jinyi Wang Ruihua Yang Yu Ke Liying Ma Hongmin Liu School of Pharmaceutical Sciences Zhengzhou University Collaborative Innovation Center of New Drug Research and Safety Evaluation
LSD1 plays an important role in the development and progression of *** the basis of the study of LSD1 inhibitor system,two series new compounds with homo-triazine skeleton were designed and *** the LSD1 inhibitory act... 详细信息
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Design,synthesis and biological activities of 2,3-dihydroquinazolin-4(1H)-one derivatives as TRPM2 inhibitors
Design,synthesis and biological activities of 2,3-dihydroqui...
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11世界华人药物化学研讨会iscmc 2018
作者: Han Zhang Huan Liu Xiao Luo Wei Yang Peilin Yu Liangren Zhang Lihe Zhang State Key Laboratory of Natural and Biomimetic Drugs School of Pharmaceutical SciencesPeking University Department of Toxicology School of Public HealthZhejiang University Department of Neurobiology School of MedicineZhejiang University
Transient receptor potential melastatin 2(TRPM2),a Ca-permeable cationic channel,plays critical roles in insulin release,cytokine production,body temperature regulation and cell death as a reactive oxygen species(... 详细信息
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Targeted inhibition of Rictor/mTORC2 suppresses tumorigenesis and enhances the therapeutic efficacy of mTOR inhibitors in esophageal squamous cell carcinoma
Targeted inhibition of Rictor/mTORC2 suppresses tumorigenesi...
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11世界华人药物化学研讨会iscmc 2018
作者: Mengying Zhang Yandan Ren Yang Wang Tianli Fan Ang Jia Guiqin Hou Zhaoming Lu School of Pharmaceutical Sciences Zhengzhou University Department of Pharmacology School of Basic MedicineZhengzhou University Collaborative Innovation Center of Cancer Chemoprevention
Esophageal squamous cell carcinoma(ESCC) is one of popular malignant tumors in *** dysregulation of mTOR pathway had been confirmed in many human cancers including ESCC and the antitumor effect of RAD001,the inhibitor... 详细信息
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Effects of clostridium butyricum on growth performance,serum biochemical parameters,antioxidant capacity and immune function of weaning calves
Effects of clostridium butyricum on growth performance,serum...
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11世界华人药物化学研讨会iscmc 2018
作者: Wenxi Li Enyue Yao Xin Liu Zhou Shuang Zhang Liyang Zhang Yonggen Animal Science and Technology Collage Northeast Agricultural University
Clostridium butyrate as a new microecological preparation has the characteristics of heat resistance,acid resistance and antibiotic *** butyrate is not only effective in the treatment of human intestinal tract disorde... 详细信息
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