Objective Bim is a BH3-only member of the Bcl-2 family, previous research showed Bim could induce the apoptosis of cardiomyocytes in rat model of myocardial infarction,the area of infarction and the expression of Bim ...
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Objective Bim is a BH3-only member of the Bcl-2 family, previous research showed Bim could induce the apoptosis of cardiomyocytes in rat model of myocardial infarction,the area of infarction and the expression of Bim were increased sharply when its subjected to cold stress,but the mechanism is unclear. To investigate the relationship between Pim-2 and Bim in cardiomyocytes when subjected to deeper temperature(25℃), and discuss the biological functions of *** Cultured rat cardiomyocytes H9c2 cells,cells were exposed to
Objective Coronary artery disease(CAD)is a major cause of death ***,studies have disclosed soluble CIM0 hgand(sCD40L),one of the inflammatory markers,in atherosclerosis development and plaque ***, the association betw...
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Objective Coronary artery disease(CAD)is a major cause of death ***,studies have disclosed soluble CIM0 hgand(sCD40L),one of the inflammatory markers,in atherosclerosis development and plaque ***, the association between sCD40L and angiographic severity
Purpose This study sought to assess the effects of probucol on atrial remodeling and atrial fibrillation(AF) promotion in alloxan-induced diabetic rabbits and to elucidate the underlying *** 40 Japanese rabbits were r...
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Purpose This study sought to assess the effects of probucol on atrial remodeling and atrial fibrillation(AF) promotion in alloxan-induced diabetic rabbits and to elucidate the underlying *** 40 Japanese rabbits were randomly assigned to a normal control group(C,n=10),alloxan-in-duced diabetic group(DM,n=10),a and probucol-treated
Background Cytochrome P450(CYP) 2J2 is expressed in the vascular endothelium and metabolizes arachidonic acid to biologically active epoxyeicosatrienoic acids(EETs).The EETs are potent endogenous vasodilators and inhi...
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Background Cytochrome P450(CYP) 2J2 is expressed in the vascular endothelium and metabolizes arachidonic acid to biologically active epoxyeicosatrienoic acids(EETs).The EETs are potent endogenous vasodilators and inhibitors of vas-
Objectives A meta-analysis was performed to determine the risk and incidence rate of arrhythmia death,cardiac death,and all-cause death in the general population with the early repolarization pattern(ERP).Background T...
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Objectives A meta-analysis was performed to determine the risk and incidence rate of arrhythmia death,cardiac death,and all-cause death in the general population with the early repolarization pattern(ERP).Background The ERP has recently been associated with vulnerability to ventricular fibrillation in case-control ***,the prognostic significance of the ERP in the general population is controversial. Methods Relevant studies published through July 31,2012, were searched and identified in the MEDLINE and Embase databases. Studies that reported risk ratio estimates with 95%
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