背景:2007年014年华山医院神经外科共介入治疗2148个动脉瘤,1764例患者,从附表1可以看出,未破裂动脉瘤的治疗呈现逐年增加的趋势。原因:1.健康意识的建立;2.检测手段的提高;3.医生对动脉瘤出血风险的认识提高;4.治疗手段的完善。文献报道:估计5%或15/百万人拥有或将有一个颅内动脉瘤(摘自:Neurosurgery,Long-term Economic Impact of Coiling Versus Clipping for Unruptured Intracranial Aneurysms)。
Autophagy,usually a cell survival mechanismin starving cells,has been implicated in cell *** the role of autophagy in the elimination of the neuromuscular junction has not been *** we show that NMJ elimination is dela...
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Autophagy,usually a cell survival mechanismin starving cells,has been implicated in cell *** the role of autophagy in the elimination of the neuromuscular junction has not been *** we show that NMJ elimination is delayed in Atgmutantsor animals with Atg *** confocal data show
Learning and memory depend on forms of neuronal plasticity that originate at the synapse yet require nuclear gene expression for ***,how synapse-to-nucleus communication supports longterm plasticity and behavior has r...
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Learning and memory depend on forms of neuronal plasticity that originate at the synapse yet require nuclear gene expression for ***,how synapse-to-nucleus communication supports longterm plasticity and behavior has remained *** synaptonuclear signaling proteins,γCa MKII stands out in its ability to rapidly shuttle Ca2+/Ca M to the nucleus and thus activate CREB-dependent
Histone deacetylase(HDAC)6 exists exclusively in cytoplasm and deacetylates cytoplasmic proteins such asα-***6 dysfunctionis associated with several pathological conditions in the central nervous *** study investigat...
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Histone deacetylase(HDAC)6 exists exclusively in cytoplasm and deacetylates cytoplasmic proteins such asα-***6 dysfunctionis associated with several pathological conditions in the central nervous *** study investigated the beneficial effects of tubastatin A(Tub A),a novel specific HDAC6 inhibitor,in a rat model of transient middle cerebral artery occlusion(MCAO)and an in vitro
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