检索结果-内蒙古大学图书馆

您好，读者！请登录

内蒙古大学图书馆

首页
概况
党建
资源
服务
科研支持
- 论文收录引用证明
- 科技查新
知识产权
档案馆
帮助

咨询与建议

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

您的常用邮箱：*

您的手机号码：*

问题描述：

当前已输入0个字，您还可以输入200个字

全部搜索
期刊论文
图书
学位论文
标准
纸本馆藏
外文资源发现
数据库导航
超星发现

高级检索

时间限定

出版年份：

文献类型

图书期刊文献学位论文多媒体

馆藏选择

电子馆藏纸本馆藏

核心期刊

全部期刊 SCI 收录期刊 SSCI 收录期刊 EI 收录期刊 CSCD 收录期刊 CSSCI 收录期刊

语言

中文英文

文献类型

期刊文献图书学位论文标准纸本馆藏

帮助

文字说明：

T=题名（书名、题名），A=作者（责任者），K=主题词，P=出版物名称，PU=出版社名称，O=机构（作者单位、学位授予单位、专利申请人），L=中图分类号，C=学科分类号，U=全部字段，Y=年（出版发行年、学位年度、标准发布年）

检索规则说明：

AND代表“并且”；OR代表“或者”；NOT代表“不包含”；(注意必须大写,运算符两边需空一格)

检索范例：

范例一：(K=图书馆学 OR K=情报学) AND A=范并思 AND Y=1982-2016
范例二：P=计算机应用与软件 AND (U=C++ OR U=Basic) NOT K=Visual AND Y=2011-2016

分类表

所选分类

>> <<

限定检索结果

文献类型

90 篇 会议
11 篇 期刊文献
7 册 图书

馆藏范围

108 篇 电子文献
0 种 纸本馆藏

日期分布

学科分类号

66 篇 工学
- 46 篇 计算机科学与技术...
- 26 篇 生物工程
- 20 篇 生物医学工程（可授...
- 13 篇 软件工程
- 9 篇 化学工程与技术
- 4 篇 电子科学与技术（可...
- 3 篇 力学（可授工学、理...
- 3 篇 机械工程
- 3 篇 电气工程
- 3 篇 控制科学与工程
- 2 篇 材料科学与工程（可...
- 2 篇 信息与通信工程
- 2 篇 环境科学与工程（可...
- 1 篇 仪器科学与技术
- 1 篇 核科学与技术
48 篇 理学
- 40 篇 生物学
- 15 篇 化学
- 10 篇 数学
- 7 篇 物理学
- 4 篇 系统科学
- 4 篇 统计学（可授理学、...
- 1 篇 地球物理学
6 篇 医学
- 5 篇 基础医学(可授医学...
- 5 篇 临床医学
- 4 篇 药学(可授医学、理...
- 1 篇 公共卫生与预防医...
2 篇 农学
2 篇 管理学
- 2 篇 图书情报与档案管...

主题

30 篇 dna
5 篇 dna computing
5 篇 bioinformatics
5 篇 fluorescence
5 篇 artificial intel...
4 篇 high performance...
4 篇 proteins
4 篇 computational bi...
4 篇 computation by a...
4 篇 algorithm analys...
3 篇 microfluidics
3 篇 computational mo...
3 篇 sequences
3 篇 middleware
3 篇 data structures
3 篇 cloud computing
3 篇 dna sequences
2 篇 dna chips
2 篇 protein engineer...
2 篇 theory of comput...

机构

3 篇 college of life ...
2 篇 huazhong univers...
2 篇 institute of mol...
2 篇 school of comput...
2 篇 univ memphis mem...
2 篇 school of scienc...
2 篇 taiyuan universi...
2 篇 computer science...
2 篇 computer enginee...
2 篇 caltech pasadena...
1 篇 univ buffalo sta...
1 篇 department of ma...
1 篇 univ ghent lab a...
1 篇 univ york dept c...
1 篇 biomedical engin...
1 篇 key laboratory o...
1 篇 health research ...
1 篇 department of co...
1 篇 univ delaware de...
1 篇 tech univ catalo...

作者

4 篇 wang luhui
4 篇 dong yafei
3 篇 hu mengyang
3 篇 wang yue
3 篇 xi sunfan
2 篇 zewen wei
2 篇 wong tit-yee
2 篇 zhihong li
2 篇 zhihua cui
2 篇 fujii teruo
2 篇 zhang david yu
2 篇 cheng meng
2 篇 brijder robert
2 篇 wang yanfeng
2 篇 schweller robert
2 篇 zicai liang
2 篇 garzon max h.
2 篇 winslow andrew
2 篇 lakin matthew r.
2 篇 lianghao li

语言

105 篇 英文
2 篇 中文
1 篇 其他

检索条件"任意字段=16th International Conference on DNA Computing and Molecular Programming, DNA 16"

共 108 条记录，以下是71-80 订阅

全选清除本页清除全部题录导出标记到"检索档案"

详细简洁

排序：

High-Fidelity dna Hybridization Using Programmable molecular dna Devices

High-Fidelity DNA Hybridization Using Programmable Molecular...

引用

16th international conference on dna computing and molecular programming

作者： Gopalkrishnan, Nikhil Chandran, Harish Reif, John Duke Univ Dept Comp Sci Durham NC 27708 USA

ISBN: (纸本)9783642183041

the hybridization of complementary nucleic acid strands is the most basic of all reactions involving nucleic acids, but has a major limitation: the specificity of hybridization reactions depends critically on the lengths of the complementary pairs of strands and can drop to very low values for sufficiently long strands. this reduction in specificity occurs especially in the presence of noise in the form of other competing strands that have sequence segments identical to the target. this limits the scale and accuracy of biotechnology and nanotechnology applications which depend on hybridization reactions. Our paper develops techniques for ensuring specific high-fidelity dna hybridization reactions for target strands of arbitrary length. Our protocol is executed autonomously, without external mediation and driven by a series of conversions of single stranded dna into duplex dna that help overcome kinetic energy traps, similar to dna walkers.

关键词： dna hybridization strand displacement

来源：评论

学校读者我要写书评

暂无评论

Search and Validation of Short Genome-Wide Biomarkers for Bacterial Biological Phylogenies

Search and Validation of Short Genome-Wide Biomarkers for Ba...

引用

16th international conference on dna computing and molecular programming

作者： Garzon, Max H. Wong, Tit-Yee Univ Memphis Memphis TN 38152 USA

ISBN: (纸本)9783642183041

We continue the exploration of dna-based indexing as a universal coordinate system in dna spaces to characterize very large groups (families, genera, and even phylla) of organisms on a uniform biomarker reference system, a comprehensive "Atlas of Life", as it is or as it could be on earth. We provide a second confirmation that dna noncrosshybridizing (nxh) sets can be successfully applied to infer ab-alitio phylogenetic trees by providing a method to measure distances among entire genomes indexed by sets of short oligonucleotides selected so as to minimize crosshybridization. these phylogenies are solidly established and well accepted in bacterial biology, albeit done by analyses of relatively small segments of highly conserved rybozomic dna. Second, it is further demonstrated that dna indexing does provide novel and principled genome-wide predictions into the phylogenesis of organisms hitherto inaccessible by current methods, such as a prediction of the origin of the Salmonella plasmid 50 as being acquired horizontally, likely from some bacteria somewhat related to Yesinia. We conclude with some discussion about the scalability and potential of this method to develop a comprehensive tree of life based on genome-wide methods.

关键词： dna codeword design noncrosshybridizing oligonucleotide bases phylogenetic analysis genomic signatures dna chips 16S rRNA tree of life

来源：评论

学校读者我要写书评

暂无评论

Optimizing Tile Concentrations to Minimize Errors and Time for dna Tile Self-assembly Systems

Optimizing Tile Concentrations to Minimize Errors and Time f...

引用

16th international conference on dna computing and molecular programming

作者： Chen, Ho-Lin Kao, Ming-Yang CALTECH Ctr Math Informat Pasadena CA 91101 USA Northwestern Univ Dept Elect Engn & Comp Sci Evanston IL USA

ISBN: (纸本)9783642183041

dna tile self-assembly has emerged as a rich and promising primitive for nano-technology. this paper studies the problems of minimizing assembly time and error rate by changing the tile concentrations because changing the tile concentrations is easy to implement in actual lab experiments. We prove that setting the concentration of tile T-i proportional to the square root of N-i where N-i is the number of times T-i appears outside the seed structure in the final assembled shape minimizes the rate of growth errors for rectilinear tile systems. We also show that the same concentrations minimize the expected assembly time for a feasible class of tile systems. Moreover, for general tile systems, given tile concentrations, we can approximate the expected assembly time with high accuracy and probability by running only a polynomial number of simulations in the size of the target shape.

关键词： Self assembly

来源：评论

学校读者我要写书评

暂无评论

Scalable, Time-Responsive, Digital, Energy-Efficient molecular Circuits Using dna Strand Displacement

Scalable, Time-Responsive, Digital, Energy-Efficient Molecul...

引用

16th international conference on dna computing and molecular programming

作者： Chiniforooshan, Ehsan Doty, David Kari, Lila Seki, Shinnosuke Univ Western Ontario Dept Comp Sci London ON Canada

ISBN: (纸本)9783642183041

We propose a novel theoretical biomolecular design to implement any Boolean circuit using the mechanism of dna strand displacement. the design is scalable: all species of dna strands can in principle be mixed and prepared in a single test tube, rather than requiring separate purification of each species, which is a barrier to large-scale synthesis. the design is time-responsive: the concentration of output species changes in response to the concentration of input species, so that time-varying inputs may be continuously processed. the design is digital: Boolean values of wires in the circuit are represented as high or low concentrations of certain species, and we show how to construct a single-input, single-output signal restoration gate that amplifies the difference between high and low, which can be distributed to each wire in the circuit to overcome signal degradation. this means we can achieve a digital abstraction of the analog values of concentrations. Finally, the design is energy-efficient: if input species are specified ideally (meaning absolutely 0 concentration of unwanted species), then output species converge to their ideal concentrations at steady-state, and the system at steady-state is in (dynamic) equilibrium, meaning that no energy is consumed by irreversible reactions until the input again changes.

关键词： Timing circuits

来源：评论

学校读者我要写书评

暂无评论

Precise control of dna orientation for improved functionlity in protein binding microarrays

Precise control of DNA orientation for improved functionlity...

引用

IEEE/LEOS international conference on Optical MEMS

作者： Philipp Spuhler Xirui Zhang Margo Monroe Joseph Greenspun M. Selim Unlu Laura Sola Marcella Chiari Biomedical Engineering Boston University Boston USA Institute for Chemistry of Molecular Recognition Italian National Research Council Milan Italy

We demonstrate controlled orientation of surface anchored dna and utilize spectral self-interference fluorescent microscopy (SSFM) to measure fluorophore height with sub-nm precision to precisely quantify dna orientat... 详细信息

关键词： Polymers Probes dna Proteins Protein engineering Fluorescence

来源：评论

学校读者我要写书评

暂无评论

Nanoslit biosensor with single-pixel resolved kinetics capability: Finite element method and experimental results

Nanoslit biosensor with single-pixel resolved kinetics capab...

引用

international conference on Solid State Sensors and Actuators (TRANSDUCERS)

作者： T. Leichlé C.F. Chou LAAS CNRS Toulouse France UPS INSA INP ISAE LAAS Université de Toulouse Toulouse France Institute of Physics Academia Sinica Taipei Taiwan

We have recently presented dna hybridization experiments suggesting that biofunctionalized nanoslits can be used as (1) ultra-fast biosensors with the ability to observe reaction kinetics at the single-pixel level and (2) biofilters based on molecular affinity [1]. In this paper, we provide simulation results from finite element analysis supporting our experimental observations.

关键词： Kinetic theory Fluorescence Biosensors Probes Finite element methods Biological system modeling dna

来源：评论

学校读者我要写书评

暂无评论

Nanobiodevice based single molecule and cell sensing for cancer diagnosis and in vivo imaging for stem cell therapy

Nanobiodevice based single molecule and cell sensing for can...

引用

international conference on Solid State Sensors and Actuators (TRANSDUCERS)

作者： Y. Baba Department of Applied Chemistry School of Engineering FIRST Research Center of Innovative Nanobiodevice Department of Advanced Medical Science School of Medicine University of Nagoya Nagoya Japan Health Research Institute National Institute for Advanced Industrial Science and Technology Takamatsu Japan

Nanobiodevices are developed to analyze biomolecules and cells for genome and proteome analysis. In this article, I will describe numerous advantages of nanobiodivces, especially in the biological, medical, and clinical applications I also describe the development of nanopillar device for the ultrafast separation of dna and nanoball materials for the fast separation of wide range of dna fragments. I developed new synthetic method of quantum dots (QDs) based on the appropriate cluster confirmation by the ab initio molecular orbital calculation. QDs are applied to in vivo imaging of stem cell for stem cell therapy and the theranostic device for cancer diagnosis and therapy. Because of the high efficiency of nanobiodevice in the biomolecular and cellular analysis, numerous types of nanobiodevices are developed and applied to the diagnosis of diseases, including cancer, diabetes, hypertension, and infection diseases.

关键词： dna Cancer Nanobioscience Biomedical imaging Quantum dots Stem cells

来源：评论

学校读者我要写书评

暂无评论

A parylene-based flexible electroporation chip applicable for in vivo gene and siRNA delivery

A parylene-based flexible electroporation chip applicable fo...

引用

international conference on Solid State Sensors and Actuators (TRANSDUCERS)

作者： Zewen Wei Yuanyu Huang Deyao Zhao Zicai Liang Zhihong Li National Key Laboratory of Science and Technology on Micro Nano Fabrication Institute of Microelectronics Peking University China Institute of Molecular Medicine Peking University China

We report a parylene-based flexible electroporation chip for in vivo nucleic acid delivery. Benefited from the flexibility of parylene film, our chip fits the natural shape of the electroporated objects, thereby provides a uniform electric field over a large area. In addition, the subject is less likely to be harmed owing to the chip features, including good biocompatibility, less invasive electroporation and lower applied voltage because of smaller space between electrodes. these characteristics offer vast potential for applications of implantable electroporation devices. Using the proposed chip, we achieved successful plasmid dna expression and siRNA transfection in both healthy mouse tissue and living tumor with excellent efficacy (90%).

关键词： Tumors dna Mice In vivo Electrodes Fluorescence Muscles

来源：评论

学校读者我要写书评

暂无评论

Efficient and high-throughput electroporation chips

Efficient and high-throughput electroporation chips

引用

international conference on Solid State Sensors and Actuators (TRANSDUCERS)

作者： Zhihong Li Zewen Wei Xueming Li Quan Du Zicai Liang National Key Laboratory of Science and Technology on Micro/Nano Fabrication Institute of Microelectronics Peking University China Institute of Molecular Medicine Peking University China

To fulfill demands of high efficient in vitro and in vivo nucleic acid delivery, three types of electroporation microchips were developed. To better fit the standard multi-well plate, we designed a chip with annual interdigital electrodes which generate even electric field. High efficient dna and siRNA delivery was achieved on both supernatant and adherent cells. the parylene based substrate was employed to realize in vivo electroporation. the flexible film fits the natural shape of the electroporated objects and has good biocompatibility, which makes the chip potential for implantable electroporation devices. Besides, to meet requirements of continuous cell treatment, we designed a flow-type electroporation chip, in which the sheath flow was employed to isolate cells from harmful effects due to water electrolysis around electrodes.

关键词： Electrodes dna In vivo Microfluidics Tumors Electric fields Mice

来源：评论

学校读者我要写书评

暂无评论

Fully integraed droplet based point-of-care platform for molecular detection from crude biosamples

Fully integraed droplet based point-of-care platform for mol...

引用

international conference on Solid State Sensors and Actuators (TRANSDUCERS)

作者： Yi Zhang Seungkyung Park Samuel Yang Tza-Huei Wang Sidney Kimmel Comprehensive Cancer Center Johns Hopkins University USA Department of Emergency Medicine Johns Hopkins University USA Department of Biomedical Engineering Johns Hopkins University USA Center of Cancer Nanotechnology Excellence at Johns Hopkins Johns Hopkins University USA

this paper reports a droplet microfluidic, sample-to-answer platform for the detection of disease biomarkers and infectious pathogens using crude biosamples. the platform exploited the dual functionality of silica superparamagnetic particles (SSP) for solid phase extraction of dna and magnetic actuation. this enabled the integration of sample preparation and genetic analysis within discrete droplets, including the steps of cell lysis, dna binding, washing, elution, amplification and detection. the microfluidic device was self contained, with all reagents stored in droplets, thereby eliminating the need for fluidic coupling to external reagent reservoirs. the device incorporated unique surface topographic features to assist droplet manipulation. Pairs of micro-elevations are created to form slits that facilitate efficient splitting of SSP from droplets. In addition, a compact sample handling stage, which integrated the magnet manipulator, the droplet microfluidic device and a Peltier thermal cycler, was built for convenient droplet manipulation and real-time detection. Feasibility of the platform was demonstrated by analysing ovarian cancer biomarker Rsf-1 and detecting Escherichia coli with the real time polymerase chain reaction and the real time helicase dependent amplification.

关键词： Surface topography Microfluidics Fluorescence Real time systems Biomarkers Cancer dna

来源：评论

学校读者我要写书评

暂无评论

没有更多数据了...

全选清除本页清除全部题录导出标记到“检索档案”

共11页 << < 2 3 4 5 6 7 8 9 10 11 > >>

检索报告对象比较合并检索0

隐藏清空

合并搜索

回到顶部

执行限定条件

内容：

评分：

请选择保存的检索档案：

请选择收藏分类：

订阅名称：

通借通还

温馨提示：

图书名称：

借书校区：

取书校区：

手机号码：

邮箱地址：

一卡通帐号：

电话和邮箱必须正确填写，我们会与您联系确认。

联系人：

所在院系：

联系邮箱：

联系电话：

内蒙古自治区呼和浩特市赛罕区大学西街235号邮编: 010021

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：