the proceedings contain 11 papers. the topics discussed include: Turing universality of step-wise and stage assembly at temperature 1;a type system for dnaQL;deterministic function computation with chemical reaction n...
ISBN:
(纸本)9783642322075
the proceedings contain 11 papers. the topics discussed include: Turing universality of step-wise and stage assembly at temperature 1;a type system for dnaQL;deterministic function computation with chemical reaction networks;reachability bounds for chemical reaction networks and strand displacement systems;synthesizing minimal tile sets for complex patterns in the framework of patterned dna self-assembly;a geometric approach to Gibbs energy landscapes and optimal dna codeword design;a dna based molecular logic gate capable of a variety of logical operations;deciding whether a regular language is generated by a splicing system;probabilistic reasoning with a Bayesian dna device based on strand displacement;dna self-assembly and computation studied with a coarse-grained dynamic bonded model;and space and energy efficient computation withdna strand displacement systems.
In this paper, we propose an output reproducible framework that executes parallel sequence comparison algo rithms, computingthe edit distance. the framework generates tables/graphics and linear regressions that can b...
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A large number (265) of burials from 1731-1838 were discovered in sealed crypts of the Dominican Church, Vac, Hungary in 1994. Many bodies were naturally mummified, so that both soft tissues and bones were available. ...
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A large number (265) of burials from 1731-1838 were discovered in sealed crypts of the Dominican Church, Vac, Hungary in 1994. Many bodies were naturally mummified, so that both soft tissues and bones were available. Contemporary archives enabled the determination of age at death, and the identification of family groups. In some cases, symptoms before death were described and, occasionally, occupation. Initial radiological examination of a small number of individuals had indicated calcified lung lesions and demonstrable acid-fast bacteria suggestive of tuberculosis infection. Tuberculosis was endemic in 18th-19th century Europe, so human remains should contain detectable Mycobacterium tuberculosis complex (MTB) dna, enabling comparisons with modern isolates. therefore, a comprehensive examination of 168 individuals for the presence of MTB dna was undertaken. Specific dna amplification methods for MTB showed that 55% of individuals were positive and that the incidence varied according to age at death and sampling site in the body. Radiographs were obtained from 27 individuals and revealed an association between gross pathology and the presence of MTB dna. there was an inverse relationship between PCR positivity and MTB target sequence size. In some cases, the preservation of MTB dna was excellent, and several target gene sequences could be detected from the same sample. this information, combined with MTB dna sequencing data and molecular typing techniques, will enable us to study the past epidemiology of TB infection, and extends the timeframe for studying changes in molecular fingerprints. Am J Phys Anthropol 120:144-152, 2003. (C) 2003 Wiley-Liss, Inc.
As new genes are sequenced, it is common for molecular biologists to compare the new gene's dna to known sequences. One simple form of dna sequence comparison is done by solving the Longest Common Subsequence (LCS...
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ISBN:
(纸本)9780889866386
As new genes are sequenced, it is common for molecular biologists to compare the new gene's dna to known sequences. One simple form of dna sequence comparison is done by solving the Longest Common Subsequence (LCS) problem. In this paper, we propose a parallel algorithm and specialized FPGA-based processor (the associative ASC Processor with reconfigurable 2D mesh) to solve the exact and approximate match LCS problems. this solution uses inexpensive hardware and can be reconfigured as new analysis techniques are developed, making it particularly attractive for processing biosequences.
this book constitutes the refereed proceedings of the 18th international conference on dna computing and molecular programming, dna 18, held in Aarhus, Denmark, in August 2012.the 11 full papers presented were careful...
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ISBN:
(数字)9783642322082
ISBN:
(纸本)9783642322075
this book constitutes the refereed proceedings of the 18th international conference on dna computing and molecular programming, dna 18, held in Aarhus, Denmark, in August 2012.
the 11 full papers presented were carefully selected from 37 submissions. the papers are organized in topical sections on advancing the engineering and science of biology and chemistry from the point of view of computer science, physics, and mathematics.
Chemical reaction networks (CRN's) are important models of molecularprogrammingthat can be realized by logically reversible, and thus energy efficient, dna strand displacement systems (DSD's). Qian et al. [1...
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In this paper, a fiber SERS-dna probe was fabricated with femtosecond laser ablation and laser-induced silver particle deposition, and a single dna strand with a stem-ring molecular beacon was modified onto the probe....
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ISBN:
(纸本)9781728127644
In this paper, a fiber SERS-dna probe was fabricated with femtosecond laser ablation and laser-induced silver particle deposition, and a single dna strand with a stem-ring molecular beacon was modified onto the probe. Deafness gene was detected in the target solution by monitoring the SERS signal intensity of the molecular beacon. the experimental results showed that low dna concentration down to 10-10 M could be successfully detected with such a fiber SERS-dna probe, which shows an alternative method for the detection of virulence gene.
We describe the interaction of radiation with a double-stranded dna molecule and withthe structural water surrounding it. the results, which include a detailed picture of dnamolecular alterations, as well as their y...
We describe the interaction of radiation with a double-stranded dna molecule and withthe structural water surrounding it. the results, which include a detailed picture of dnamolecular alterations, as well as their yield and spatial disposition, were obtained withthe aid of Monte Carlo codes that simulate, event-by-event and simultaneously, direct and indirect effects. these calculations make use of explicit quantum-mechanical descriptions of the electronic structure of condensed water and of a homopolynucleotide chain. From these we obtain, via the dielectric response function of the two systems, epsilon (q, omega), the interaction probabilities necessary in the transport codes.
We present a computing model based on the dna strand displacement technique which performs Bayesian inference. the model will take single stranded dna as input data, representing the presence or absence of a specific ...
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Recently we have introduced a formal graph-based data model for dna complexes geared towards database applications. the model is accompanied by the programming language dnaQL for querying databases in dna. Due to natu...
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